Search Results - "Moriuchi, Hiroshi"

The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice by Tanaka, Yuta, Ishitsuka, Yoichi, Hayasaka, Marina, Yamada, Yusei, Miyata, Keishi, Endo, Motoyoshi, Kondo, Yuki, Moriuchi, Hiroshi, Irikura, Mitsuru, Tanaka, Ken-ichiro, Mizushima, Tohru, Oike, Yuichi, Irie, Tetsumi

“…The purpose of this study was to evaluate the role of CCAAT/enhancer-binding protein homologous protein (CHOP), an important transcription factor that…”
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Survey of satisfaction regarding palliative care provided to patients who died at home or in a hospital by Katsuki, Masaaki, Nakamata, Momoka, Ezaki, Arisa, Yamanaka, Sayaka, Imamura, Sakiko, Honda, Chika, Kubota, Toshio, Moriuchi, Hiroshi, Irikura, Mitsuru

“…Improvement in quality of life (QoL) of patients is one of the most important goals of palliative care, but evaluation of QoL of patients is difficult. To…”
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A Selective Thromboxane A2 (TXA2) Synthase Inhibitor, Ozagrel, Attenuates Lung Injury and Decreases Monocyte Chemoattractant Protein-1 and Interleukin-8 mRNA Expression in Oleic Acid–Induced Lung Injury in Guinea Pigs by Ishitsuka, Yoichi, Moriuchi, Hiroshi, Isohama, Yoichiro, Tokunaga, Hidehiro, Hatamoto, Keita, Kurita, Sumika, Irikura, Mitsuru, Iyama, Ken-ichi, Irie, Tetsumi

“…This study examined the effect of ozagrel, a thromboxane A2 synthase inhibitor, on the accumulation of leucocytes and chemokine mRNA expression in lungs…”
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The Effects of Single Nucleotide Polymorphisms in CYP2A13 on Metabolism of 5-Methoxypsoralen by GOTO, Tatsushi, MORIUCHI, Hiroshi, XUEJUN FU, IKEGAWA, Tomoyo, MATSUBARA, Toshiyuki, GANG CHANG, UNO, Tomohide, MORIGAKI, Kenichi, ISSHIKI, Kunio, IMAISHI, Hiromasa

“…A number of studies have demonstrated that cytochrome P450 (P450) converts furanocoumarin derivatives into reactive molecules, which form covalent bonds to…”
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Molecular Characterization of a Novel Type of Prostamide/Prostaglandin F Synthase, Belonging to the Thioredoxin-like Superfamily by Moriuchi, Hiroshi, Koda, Noriko, Okuda-Ashitaka, Emiko, Daiyasu, Hiromi, Ogasawara, Kensuke, Toh, Hiroyuki, Ito, Seiji, Woodward, David F., Watanabe, Kikuko

“…Prostaglandin F (PGF) ethanolamide (prostamide F) synthase, which catalyzed the reduction of prostamide H2 to prostamide F2α, was found in mouse and swine…”
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An evaluation of novel biological activity in a crude extract from Hemerocallis fulva L. var. sempervirens M. Hotta by Taguchi, Kazuaki, Yamasaki, Keishi, Maesaki, Hiroki, Tokuno, Masahiro, Okazaki, Shoko, Moriuchi, Hiroshi, Takeshita, Keizo, Otagiri, Masaki, Seo, Hakaru

“…Hemerocallis fulva L. var. sempervirens M. Hotta (kwanso) represents an exceptional resource for identifying and developing new phytomedicines for the…”
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Effects of Bolus Injection of Soybean-Based Fat Emulsion and Fatty Acids on Pulmonary Gas Exchange Function by Ishitsuka, Yoichi, Moriuchi, Hiroshi, Yang, Changqing, Golbidi, Saeid, Irikura, Mitsuru, Irie, Tetsumi

“…To determine whether or not a “bolus injection” of soybean-based fat emulsion (SFE), which contains oleic acid (OA), a potent lung-toxic unsaturated C-18 fatty…”
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Preferential domain orientation of HMGB2 determined by the weak intramolecular interactions mediated by the interdomain linker by Uewaki, Jun-ichi, Kamikubo, Hironari, Kurita, Jun-ichi, Hiroguchi, Noriteru, Moriuchi, Hiroshi, Yoshida, Michiteru, Kataoka, Mikio, Utsunomiya-Tate, Naoko, Tate, Shin-ichi

“…[Display omitted] ► Preferential domain arrangement of the domains in HMGB2 in solution was determined. ► The preferential domain orientation was mediated the…”
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The relaxant action of nicorandil in bovine tracheal smooth muscle by Yunoki, Motonari, Nakahara, Tsutomu, Moriuchi, Hiroshi, Sakamoto, Kenji, Ishii, Kunio

“…The relaxant mechanisms of nicorandil were examined by comparing its effects with those of sodium nitroprusside and cromakalim in bovine tracheal smooth…”
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Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs by Somekawa-Kondo, Tomoko, Yamaguchi, Keitaro, Ishitsuka, Yoichi, Ito, Sachiko, Tanaka, Kaori, Irikura, Mitsuru, Moriuchi, Hiroshi, Takahama, Kazuo, Ando, Yukio, Yamazaki, Toshio, Irie, Tetsumi

“…Objectives  To establish whether aminophylline, administered at usual doses for rodents in pharmacological studies, induces brain injury in systemic hypoxaemia…”
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The Ethical Kampo Formulation Sho-Seiryu-To (TJ-19) Prevents Bleomycin-Induced Pulmonary Fibrosis in Rats by Yang, Chang-qing, Sun, Peng-yuan, Ding, Da-zhi, Moriuchi, Hiroshi, Ishitsuka, Yoichi, Irikura, Mitsuru, Irie, Tetsumi

“…The effects of Sho-seiryu-to (TJ-19), an ethical Kampo formulation, on bleomycin (BLM)-induced pulmonary fibrosis in rats was examined. Pulmonary fibrosis was…”
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Protection afforded by a herbal medicine, Sho-seiryu-to (TJ-19), against oleic acid-induced acute lung injury in guinea-pigs by Yang, Chang-qing, Ishitsuka, Yoichi, Moriuchi, Hiroshi, Golbidi, Saeid, Jin, Zhen-ji, Irikura, Mitsuru, Irie, Tetsumi

“…Objectives The effect of a herbal medicine, Sho‐seiryu‐to (TJ‐19), on oleic acid‐induced lung injury, an animal model of acute respiratory distress syndrome or…”
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Oxidative Stress in Early Stage of Acute Lung Injury Induced with Oleic Acid in Guinea Pigs by Yang, Changqing, Moriuchi, Hiroshi, Takase, Junko, Ishitsuka, Yoichi, Irikura, Mitsuru, Irie, Tetsumi

“…Changes in several biomarkers in bronchoalveolar lavage fluid (BALF) during an early stage of lung injury induced with oleic acid were examined in guinea pigs…”
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Preventive Effect of Tranilast on Oleic Acid-Induced Lung Injury in Guinea Pigs by Ishitsuka, Yoichi, Moriuchi, Hiroshi, Yang, Changqing, Kurita, Sumika, Golbidi, Saeid, Irikura, Mitsuru, Irie, Tetsumi

“…Acute respiratory distress syndrome or acute lung injury (ARDS)/(ALI) involve the severe lung injury with pulmonary vascular hyper-permeability and hypoxemia…”
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Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy by Utsuki, Tadanobu, Uchimura, Nao, Irikura, Mitsuru, Moriuchi, Hiroshi, Holloway, Harold W, Yu, Qian-Sheng, Spangler, Edward L, Mamczarz, Jacek, Ingram, Donald K, Irie, Tetsumi, Greig, Nigel H

“…Phenserine (PS) was designed as a selective acetylcholinesterase (AChE) inhibitor, with a tartrate form (PST) for oral administration in mild to moderate…”
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Preventive Effect of Phosphoenolpyruvate on Hypoxemia Induced by Oleic Acid in Guinea Pigs by Golbidi, Saeid, Moriuchi, Hiroshi, Yang, Changqing, Irikura, Mitsuru, Irie, Tetsumi, Hamasaki, Naotaka

“…Oleic acid-induced hypoxemia is an animal model of acute respiratory distress syndrome (ARDS). Increased capillary permeability is a cause of hypoxemia in lung…”
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Relaxant effect of YM976, a novel phosphodiesterase 4 inhibitor, on bovine tracheal smooth muscle by Moriuchi, Hiroshi, Nakahara, Tsutomu, Maruko, Takeshi, Sakamoto, Kenji, Ishii, Kunio

“…Effects of 4-(3-chlorophenyl)-1,7-diethylpyrido[2,3- d]pyrimidin-2(1 H)-one (YM976), a novel and selective phosphodiesterase type 4 inhibitor, on tension and…”
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Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs by Ishitsuka, Yoichi, Moriuchi, Hiroshi, Hatamoto, Keita, Takase, Junko, Irikura, Mitsuru, Irie, Tetsumi, Yang, Changqing, Golbidi, Saeid

“…ABSTRACT An intravenous injection of oleic acid into animals can produce a lung injury with hypoxaemia and pulmonary vascular hyper‐permeability. Although…”
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Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle by Nakahara, Tsutomu, Yunoki, Motonari, Moriuchi, Hiroshi, Mitani, Akiko, Sakamoto, Kenji, Ishii, Kunio

“…The effects of ibudilast, an inhibitor of phosphodiesterases (PDEs), on tension, levels of guanosine 3',5'-cyclic monophosphate (cGMP) and adenosine…”
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Comparison of quality of life and activity of daily living status of patients with myasthenia gravis treated with low-dose and high-dose prednisolone by Katsuki, Masaaki, Sugahara, Hirotaka, Kojima, Yuka, Yamashita, Kanae, Moriuchi, Hiroshi, Kubota, Toshio, Masuda, Masayuki, Irikura, Mitsuru

“…To compare the effect of low-dose prednisolone (PSL) (≤5 mg/day) and high-dose PSL (>5 mg/day) therapy on the QOL and activity of daily living (ADL) in…”
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