Search Results - "Moritz, RL"

Advances and Utility of the Human Plasma Proteome by Deutsch, Eric W, Omenn, Gilbert S, Sun, Zhi, Maes, Michal, Pernemalm, Maria, Palaniappan, Krishnan K, Letunica, Natasha, Vandenbrouck, Yves, Brun, Virginie, Tao, Sheng-ce, Yu, Xiaobo, Geyer, Philipp E, Ignjatovic, Vera, Moritz, Robert L, Schwenk, Jochen M

“…The study of proteins circulating in blood offers tremendous opportunities to diagnose, stratify, or possibly prevent diseases. With recent technological…”
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The 5300-year-old Helicobacter pylori genome of the Iceman by Maixner, Frank, Krause-Kyora, Ben, Turaev, Dmitrij, Herbig, Alexander, Hoopmann, Michael R., Hallows, Janice L., Kusebauch, Ulrike, Vigl, Eduard Egarter, Malfertheiner, Peter, Megraud, Francis, O'Sullivan, Niall, Cipollini, Giovanna, Coia, Valentina, Samadelli, Marco, Engstrand, Lars, Linz, Bodo, Moritz, Robert L., Grimm, Rudolf, Krause, Johannes, Nebel, Almut, Moodley, Yoshan, Rattei, Thomas, Zink, Albert

“…The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It has dispersed globally with its human host, resulting in a distinct…”
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Selected reaction monitoring mass spectrometry of mastitis milk reveals pathogen-specific regulation of bovine host response proteins by Kusebauch, Ulrike, Hernández-Castellano, Lorenzo E, Bislev, Stine L, Moritz, Robert L, Røntved, Christine M, Bendixen, Emøke

“…Mastitis is a major challenge to bovine health. The detection of sensitive markers for mastitis in dairy herds is of great demand. Suitable biomarkers should…”
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The Iceman’s Last Meal Consisted of Fat, Wild Meat, and Cereals by Maixner, Frank, Turaev, Dmitrij, Cazenave-Gassiot, Amaury, Janko, Marek, Krause-Kyora, Ben, Hoopmann, Michael R., Kusebauch, Ulrike, Sartain, Mark, Guerriero, Gea, O’Sullivan, Niall, Teasdale, Matthew, Cipollini, Giovanna, Paladin, Alice, Mattiangeli, Valeria, Samadelli, Marco, Tecchiati, Umberto, Putzer, Andreas, Palazoglu, Mine, Meissen, John, Lösch, Sandra, Rausch, Philipp, Baines, John F., Kim, Bum Jin, An, Hyun-Joo, Gostner, Paul, Egarter-Vigl, Eduard, Malfertheiner, Peter, Keller, Andreas, Stark, Robert W., Wenk, Markus, Bishop, David, Bradley, Daniel G., Fiehn, Oliver, Engstrand, Lars, Moritz, Robert L., Doble, Philip, Franke, Andre, Nebel, Almut, Oeggl, Klaus, Rattei, Thomas, Grimm, Rudolf, Zink, Albert

“…The history of humankind is marked by the constant adoption of new dietary habits affecting human physiology, metabolism, and even the development of…”
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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins by Verhagen, Anne M, Ekert, Paul G, Pakusch, Miha, Silke, John, Connolly, Lisa M, Reid, Gavin E, Moritz, Robert L, Simpson, Richard J, Vaux, David L

“…To identify proteins that bind mammalian IAP homolog A (MIHA, also known as XIAP), we used coimmunoprecipitation and 2D immobilized pH gradient/SDS PAGE,…”
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Mass Fingerprinting of Complex Mixtures: Protein Inference from High-Resolution Peptide Masses and Predicted Retention Times by Moruz, Luminita, Hoopmann, Michael R, Rosenlund, Magnus, Granholm, Viktor, Moritz, Robert L, Käll, Lukas

“…In typical shotgun experiments, the mass spectrometer records the masses of a large set of ionized analytes but fragments only a fraction of them. In the…”
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HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins by Verhagen, Anne M., Silke, John, Ekert, Paul G., Pakusch, Miha, Kaufmann, Hitto, Connolly, Lisa M., Day, Catherine L., Tikoo, Anjali, Burke, Richard, Wrobel, Carolyn, Moritz, Robert L., Simpson, Richard J., Vaux, David L.

“…Inhibitor of apoptosis (IAP) proteins inhibit caspases, a function counteracted by IAP antagonists, insect Grim, HID, and Reaper and mammalian DIABLO/Smac. We…”
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Mining a Tandem Mass Spectrometry Database To Determine the Trends and Global Factors Influencing Peptide Fragmentation by Kapp, Eugene A, Schütz, Frédéric, Reid, Gavin E, Eddes, James S, Moritz, Robert L, O'Hair, Richard A. J, Speed, Terence P, Simpson, Richard J

“…A database of 5500 unique peptide tandem mass spectra acquired in an ion trap mass spectrometer was assembled for peptides derived from proteins digested with…”
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Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D by McColl, Bradley K, Baldwin, Megan E, Roufail, Sally, Freeman, Craig, Moritz, Robert L, Simpson, Richard J, Alitalo, Kari, Stacker, Steven A, Achen, Marc G

“…Vascular endothelial growth factor (VEGF) C and VEGF-D stimulate lymphangiogenesis and angiogenesis in tissues and tumors by activating the endothelial cell…”
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Liquid-based free-flow electrophoresis-reversed-phase HPLC: a proteomic tool by Simpson, Richard J, Moritz, Robert L

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The Conserved SOCS Box Motif in Suppressors of Cytokine Signaling Binds to Elongins B and C and May Couple Bound Proteins to Proteasomal Degradation by Zhang, Jian-Guo, Farley, Alison, Nicholson, Sandra E., Willson, Tracy A., Zugaro, Lisa M., Simpson, Richard J., Moritz, Robert L., Cary, Dale, Richardson, Rachael, Hausmann, George, Kile, Benjamin J., Stephen B. H. Kent, Alexander, Warren S., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Baca, Manuel

“…The suppressors of cytokine signaling (SOCS) family of proteins act as intracellular inhibitors of several cytokine signal transduction pathways. Their…”
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A wide-ranging Pseudomonas aeruginosa PeptideAtlas build: A useful proteomic resource for a versatile pathogen by Reales-Calderón, J.A., Sun, Z., Mascaraque, V., Pérez-Navarro, E., Vialás, V., Deutsch, E.W., Moritz, R.L., Gil, C., Martínez, J.L., Molero, G.

“…Pseudomonas aeruginosa is an important opportunistic human pathogen with high prevalence in nosocomial infections. This microorganism is a good model for…”
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A Proteome Strategy for Fractionating Proteins and Peptides Using Continuous Free-Flow Electrophoresis Coupled Off-Line to Reversed-Phase High-Performance Liquid Chromatography by Moritz, Robert L, Ji, Hong, Schütz, Frédéric, Connolly, Lisa M, Kapp, Eugene A, Speed, Terence P, Simpson, Richard J

“…Extensive prefractionation is now considered to be a necessary prerequisite for the comprehensive analysis of complex proteomes where the dynamic range of…”
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Structure of the Extracellular Domains of the Human Interleukin-6 Receptor α-Chain by Varghese, J. N., Moritz, R. L., M.-Z. Lou, van Donkelaar, A., Ji, H., Ivancic, N., Branson, K. M., Hall, N. E., Simpson, R. J.

“…Dysregulated production of IL-6 and its receptor (IL-6R) are implicated in the pathogenesis of multiple myeloma, autoimmune diseases and prostate cancer. The…”
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Application of 2-D free-flow electrophoresis/RP-HPLC for proteomic analysis of human plasma depleted of multi high-abundance proteins by Moritz, Robert L., Clippingdale, Andrew B., Kapp, Eugene A., Eddes, James S., Ji, Hong, Gilbert, Sam, Connolly, Lisa M., Simpson, Richard J.

“…Free‐flow electrophoresis (FFE) and rapid (6 min) RP‐HPLC was used to fractionate human citrate‐treated plasma. Prior to analysis, the six most abundant…”
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Uropathogenic Escherichia coli use d‐serine deaminase to modulate infection of the murine urinary tract by Roesch, Paula L., Redford, Peter, Batchelet, Stephanie, Moritz, Rebecca L., Pellett, Shahaireen, Haugen, Brian J., Blattner, Frederick R., Welch, Rodney A.

“…Summary Although once thought to be unique to bacteria, d‐amino acids are also produced by mammals. For example, d‐serine is excreted in human urine at…”
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Enzymic, Phylogenetic, and Structural Characterization of the Unusual Papain-like Protease Domain of Plasmodium falciparum SERA5 by Hodder, Anthony N, Drew, Damien R, Epa, V Chandana, Delorenzi, Mauro, Bourgon, Richard, Miller, Susanne K, Moritz, Robert L, Frecklington, David F, Simpson, Richard J, Speed, Terence P, Pike, Robert N, Crabb, Brendan S

“…Serine repeat antigen 5 (SERA5) is an abundant antigen of the human malaria parasite Plasmodium falciparum and is the most strongly expressed member of the…”
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The Disulfide Bond Structure of Plasmodium Apical Membrane Antigen-1 by Hodder, A N, Crewther, P E, Matthew, M L, Reid, G E, Moritz, R L, Simpson, R J, Anders, R F

“…Apical membrane antigen-1 (AMA-1) of Plasmodium falciparum is one of the leading asexual blood stage antigens being considered for inclusion in a malaria…”
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C-terminal Extension of Truncated Recombinant Proteins in Escherichia coli with a 10Sa RNA Decapeptide by Tu, G F, Reid, G E, Zhang, J G, Moritz, R L, Simpson, R J

“…When murine interleukin-6 is overexpressed in Escherichia coli , a small population of molecules exhibits a novel C-terminal modification. Peptide mapping,…”
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CHOMPER: A bioinformatic tool for rapid validation of tandem mass spectrometry search results associated with high-throughput proteomic strategies by Eddes, James S., Kapp, Eugene A., Frecklington, David F., Connolly, Lisa M., Layton, Meredith J., Moritz, Robert L., Simpson, Richard J.

“…Current efforts aimed at developing high‐throughput proteomics focus on increasing the speed of protein identification. Although improvements in sample…”
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