Search Results - "Moritz, J"

Mechanisms and Consequences of Oxygen and Carbon Dioxide Sensing in Mammals by Cummins, Eoin P, Strowitzki, Moritz J, Taylor, Cormac T

“…Molecular oxygen (O ) and carbon dioxide (CO ) are the primary gaseous substrate and product of oxidative phosphorylation in respiring organisms, respectively…”
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White matter aging drives microglial diversity by Safaiyan, Shima, Besson-Girard, Simon, Kaya, Tuğberk, Cantuti-Castelvetri, Ludovico, Liu, Lu, Ji, Hao, Schifferer, Martina, Gouna, Garyfallia, Usifo, Fumere, Kannaiyan, Nirmal, Fitzner, Dirk, Xiang, Xianyuan, Rossner, Moritz J., Brendel, Matthias, Gokce, Ozgun, Simons, Mikael

“…Aging results in gray and white matter degeneration, but the specific microglial responses are unknown. Using single-cell RNA sequencing from white and gray…”
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A Genetically Encoded Spin Label for Electron Paramagnetic Resonance Distance Measurements by Schmidt, Moritz J, Borbas, Julia, Drescher, Malte, Summerer, Daniel

“…We report the genetic encoding of a noncanonical, spin-labeled amino acid in Escherichia coli. This enables the intracellular biosynthesis of spin-labeled…”
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Chemoselective Post‐Synthesis Modification of Pyridyl‐Substituted, Aromatic Phosphorus Heterocycles: Cationic Ligands for Coordination Chemistry by Dettling, Lea, Papke, Martin, Ernst, Moritz J., Weber, Manuela, Müller, Christian

“…Triazaphospholes are potential polydentate ligands due to the presence of both phosphorus and nitrogen donor atoms within the aromatic 5‐membered heterocycle…”
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Cell type– and brain region–resolved mouse brain proteome by Sharma, Kirti, Schmitt, Sebastian, Bergner, Caroline G, Tyanova, Stefka, Kannaiyan, Nirmal, Manrique-Hoyos, Natalia, Kongi, Karina, Cantuti, Ludovico, Hanisch, Uwe-Karsten, Philips, Mari-Anne, Rossner, Moritz J, Mann, Matthias, Simons, Mikael

“…The authors performed a comprehensive proteome analysis of the adult mouse brain, its major regions and CNS cell types at a depth of >13,000 proteins. This new…”
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Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous? by Strowitzki, Moritz J, Cummins, Eoin P, Taylor, Cormac T

“…All metazoans that utilize molecular oxygen (O ) for metabolic purposes have the capacity to adapt to hypoxia, the condition that arises when O demand exceeds…”
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Analysis of the GPR17 receptor in NG2‐glia under physiological conditions unravels a new subset of oligodendrocyte progenitor cells with distinct functions by Miralles, Antonio J., Unger, Nicole, Kannaiyan, Nirmal, Rossner, Moritz J., Dimou, Leda

“…NG2‐glia comprise a heterogeneous population of cycling cells that give rise to mature, myelinating oligodendrocytes. The mechanisms that regulate the process…”
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Age-related myelin degradation burdens the clearance function of microglia during aging by Safaiyan, Shima, Kannaiyan, Nirmal, Snaidero, Nicolas, Brioschi, Simone, Biber, Knut, Yona, Simon, Edinger, Aimee L, Jung, Steffen, Rossner, Moritz J, Simons, Mikael

“…Safaiyan et al . demonstrate that myelin fragments progressively pinch off from aged myelin sheaths and are taken up and cleared by microglia. Age-associated…”
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Experimental observations of aquifer storage and recovery in brackish aquifers using multiple partially penetrating wells by Witt, Lilli, Müller, Moritz J., Gröschke, Maike, Post, Vincent E. A.

“…Aquifer storage and recovery systems using multiple partially penetrating wells (MPPW-ASR) can form a viable solution to the problem of freshwater buoyancy…”
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AI-driven public services and the privacy paradox: do citizens really care about their privacy? by Willems, Jurgen, Schmid, Moritz J., Vanderelst, Dieter, Vogel, Dominik, Ebinger, Falk

“…Based on privacy calculus theory, we derive hypotheses on the role of perceived usefulness and privacy risks of artificial intelligence (AI) in public…”
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Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors by Wu, Yuxin, Jensen, Niels, Rossner, Moritz J, Wehr, Michael C

“…G protein-coupled receptors (GPCRs) are relevant targets for health and disease as they regulate various aspects of metabolism, proliferation, differentiation,…”
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Surgical strategies in true adenocarcinoma of the esophagogastric junction (AEG II): thoracoabdominal or abdominal approach? by Blank, Susanne, Schmidt, Thomas, Heger, Patrick, Strowitzki, Moritz J., Sisic, Leila, Heger, Ulrike, Nienhueser, Henrik, Haag, Georg Martin, Bruckner, Thomas, Mihaljevic, André L., Ott, Katja, Büchler, Markus W., Ulrich, Alexis

“…Background The optimal surgical approach for adenocarcinoma directly at the esophagogastric junction (AEG II) is still under debate. This study aims to…”
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Hypoxia-adaptive pathways: A pharmacological target in fibrotic disease? by Strowitzki, Moritz J., Ritter, Alina S., Kimmer, Gwendolyn, Schneider, Martin

“…[Display omitted] Wound healing responses are physiological reactions to injuries and share common characteristics and phases independently of the injured…”
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Assessing behavior and cognition in rodents, nonhuman primates, and humans: where are the limits of translation? by Stephan, Marius, Volkmann, Paul, Rossner, Moritz J.

“…New psychopharmacological treatments are needed for affective and nonaffective psychoses, especially for the associated negative and cognitive symptoms…”
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Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation by Kaths, J. Moritz, Hamar, Mátyás, Echeverri, Juan, Linares, Ivan, Urbanellis, Peter, Cen, Jun Yu, Ganesh, Sujani, Dingwell, Luke S., Yip, Paul, John, Rohan, Bagli, Darius, Mucsi, Istvan, Ghanekar, Anand, Grant, David, Robinson, Lisa A., Selzner, Markus

“…Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft preservation and functional improvement in kidney transplantation. We…”
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Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity by Rauschmeier, René, Gustafsson, Charlotte, Reinhardt, Annika, A‐Gonzalez, Noelia, Tortola, Luigi, Cansever, Dilay, Subramanian, Sethuraman, Taneja, Reshma, Rossner, Moritz J, Sieweke, Michael H, Greter, Melanie, Månsson, Robert, Busslinger, Meinrad, Kreslavsky, Taras

“…Tissues in multicellular organisms are populated by resident macrophages, which perform both generic and tissue‐specific functions. The latter are induced by…”
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Computing Counterinsurgency: The Hamlet Evaluation System (HES) and Databasing During the Vietnam War by Feichtinger, Moritz J

“…In 1967, the U.S. military in South Vietnam launched the Hamlet Evaluation System (HES), a new type of data-processing system comprising a demographic database…”
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Factors influencing knee adduction moment measurement: A systematic review and meta-regression analysis by Telfer, Scott, Lange, Moritz J., Sudduth, Amanda S.M.

“…•We performed a meta-regression analysis of external knee adduction moment (KAM) data.•The effect of population type, footwear type, and walking speed were…”
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FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration by Szewczyk, Barbara, Günther, René, Japtok, Julia, Frech, Moritz J., Naumann, Marcel, Lee, Hyun O., Hermann, Andreas

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder causing progressive loss of motor neurons. Mutations in Fused in sarcoma (FUS) leading to…”
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Association Between Physical Activity and Schizophrenia: Results of a 2-Sample Mendelian Randomization Analysis by Papiol, Sergi, Schmitt, Andrea, Maurus, Isabel, Rossner, Moritz J, Schulze, Thomas G, Falkai, Peter

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