Search Results - "Moritz, Eva"
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Oxidation Status of Human OGG1-S326C Polymorphic Variant Determines Cellular DNA Repair Capacity
Published in Cancer research (Chicago, Ill.) (15-04-2009)“…The hOGG1 gene encodes the DNA glycosylase that removes the mutagenic lesion 7,8-dihyro-8-oxoguanine (8-oxoG) from DNA. A frequently found polymorphism…”
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The Cellular RNA Helicase UAP56 Is Required for Prevention of Double-Stranded RNA Formation during Influenza A Virus Infection
Published in Journal of Virology (01-09-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential
Published in mSphere (26-08-2020)“…Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a devastating…”
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hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide
Published in Carcinogenesis (New York) (01-06-2014)Get full text
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Recovery of ammonia from centrate water in urban waste water treatment plants via direct contact membrane distillation: Process performance in long-term pilot-scale operation
Published in Journal of membrane science (05-02-2023)“…Our current industrial ammonia cycle is far from being sustainable – while intense energy is required to produce ammonia – almost half of it ends up in…”
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Interaction with OGG1 Is Required for Efficient Recruitment of XRCC1 to Base Excision Repair and Maintenance of Genetic Stability after Exposure to Oxidative Stress
Published in Molecular and cellular biology (01-05-2015)“…XRCC1 is an essential protein required for the maintenance of genomic stability through its implication in DNA repair. The main function of XRCC1 is associated…”
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Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques
Published in Neurobiology of disease (01-08-2001)“…Cystatin C is an essential secretory cofactor for neurogenesis with potent protease inhibitor activities. Polymorphisms of cystatin C are genetically…”
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IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization
Published in The Journal of experimental medicine (07-06-2021)“…The disease severity of influenza is highly variable in humans, and one genetic determinant behind these differences is the IFITM3 gene. As an effector of the…”
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BRD9 is a druggable component of interferon-stimulated gene expression and antiviral activity
Published in EMBO reports (05-10-2021)“…Interferon (IFN) induction of IFN-stimulated genes (ISGs) creates a formidable protective antiviral state. However, loss of appropriate control mechanisms can…”
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hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide
Published in Carcinogenesis (New York) (01-06-2014)“…The repair of 8-oxo-7,8-dihydroguanine in the DNA of mammalian cells is initiated by 8-oxoguanine DNA glycosylase (OGG1). A frequent polymorphism in the human…”
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Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential
Published in mSphere (01-08-2020)“…ABSTRACT Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a…”
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12
Antibodies against β-Amyloid Slow Cognitive Decline in Alzheimer's Disease
Published in Neuron (Cambridge, Mass.) (22-05-2003)“…To test whether antibodies against β-amyloid are effective in slowing progression of Alzheimer's disease, we assessed cognitive functions in 30 patients who…”
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Interferon-induced Antiviral Protein MxA Interacts with the Cellular RNA Helicases UAP56 and URH49
Published in The Journal of biological chemistry (07-10-2011)“…Mx proteins are a family of large GTPases that are induced exclusively by interferon-α/β and have a broad antiviral activity against several viruses, including…”
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Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments
Published in DNA repair (01-03-2013)“…► Mild hyperthermia affects cellular DNA glycosylase activities. ► Heat shock leads to a rapid inactivation of OGG1, followed by its degradation. ► OGG1 is…”
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Lack of netrin-4 modulates pathologic neovascularization in the eye
Published in Scientific reports (06-01-2016)“…Netrins are a family of matrix-binding proteins that function as guidance signals. Netrin-4 displays pathologic roles in tumorigenesis and neovascularization…”
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Generation of antibodies specific for β-amyloid by vaccination of patients with Alzheimer disease
Published in Nature medicine (01-11-2002)“…To characterize antibodies produced in humans in response to Abeta42 vaccination, we carried out immunohistochemical examinations of the brains of both…”
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Generation of antibodies specific for [beta]-amyloid by vaccination of patients with Alzheimer disease
Published in Nature medicine (01-11-2002)“…To characterize antibodies produced in humans in response to Abeta42 vaccination, we carried out immunohistochemical examinations of the brains of both…”
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Antibodies against [beta]-Amyloid Slow Cognitive Decline in Alzheimer's Disease
Published in Neuron (Cambridge, Mass.) (22-05-2003)“…To test whether antibodies against β-amyloid are effective in slowing progression of Alzheimer's disease, we assessed cognitive functions in 30 patients who…”
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Active immunization of mice with an Abeta-Hsp70 vaccine
Published in Neuro-degenerative diseases (2004)“…Heat-shock proteins are highly immunogenic. Complexed with an antigen, they act as adjuvants, inducing a humoral and cellular immune response against both the…”
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