Search Results - "Morito, Fumitaka"

Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis by Tada, Yoshifumi, Koarada, Syuichi, Morito, Fumitaka, Mitamura, Mio, Inoue, Hisako, Suematsu, Rie, Ohta, Akihide, Miyake, Kensuke, Nagasawa, Kohei

“…RP105 is a Toll-like receptor homolog expressed on B cells, dendritic cells (DCs), and macrophages. We investigated the role of RP105 in the development of…”
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Role of inducible costimulator in the development of lupus in MRL/lpr mice by Tada, Yoshifumi, Koarada, Syuichi, Tomiyoshi, Yoshiyuki, Morito, Fumitaka, Mitamura, Mio, Haruta, Yoshio, Ohta, Akihide, Nagasawa, Kohei

“…Inducible costimulator (ICOS) is a costimulatory molecule expressed in activated T cells and plays an important role in T-cell-dependent immune responses. We…”
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Two cases of antinuclear antibody negative lupus showing increased proportion of B cells lacking RP105 by KOARADA, Syuichi, IDE, Masaru, HARUTA, Yoshio, TADA, Yoshifumi, USHIYAMA, Osamu, MORITO, Fumitaka, OHTA, Akihide, NAGASAWA, Kohei

“…B cells lacking RP105 molecule, a member of the Toll-like receptor family, were increased in the peripheral blood of 2 patients with antinuclear antibody (ANA)…”
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Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism by Sherriff-Tadano, Ryoko, Ohta, Akihide, Morito, Fumitaka, Mitamura, Mio, Haruta, Yoshio, Koarada, Shuichi, Tada, Yoshifumi, Nagasawa, Kohei, Ozaki, Iwata

“…Abstract We investigated the effect of hepatocyte growth factor (HGF) on collagen metabolism in cultured fibroblasts from scleroderma (SSc) patients and…”
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Attenuating effect of castration on glomerular injury is age-dependent in unilaterally nephrectomized male Sprague-Dawley rats by Sakemi, T, Ohtsuka, N, Tomiyosi, Y, Morito, F

“…To clarify a role of sex hormones in greater susceptibility of young rats than adults to the development of focal and segmental glomerulosclerosis (FSGS), we…”
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Different effect of estrogen administration from castration on glomerular injury in unilaterally nephrectomized male Sprague-Dawley rats by Ohtsuka, N, Sakemi, T, Tomiyoshi, Y, Morito, F

“…We have already reported an equally attenuating effect of castration or estrogen administration on the development of focal segmental glomerulosclerosis (FSGS)…”
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Pharmacological effects of Dai-saiko-to on lipid biosynthesis in cultured human hepatocyte HepG2 cells by Yamamoto, K, Ogawa, Y, Yanagita, Y, Morito, F, Fukushima, N, Ozaki, I, Mizuta, T, Setoguchi, Y, Sakai, T

“…The pharmacological effects of Dai-saiko-to, a Japanese and Chinese traditional medicinal mixture (Kampohozai), on lipid biosynthesis were investigated in…”
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Genetic Analysis of Systemic Lupus Erythematosus : Association with a T Cell Receptor Restriction Fragment Length Polymorphism in Japanese Patients by MORITO, Fumitaka, HIIDA, Megumi, OHTA, Akihide, YAMAGUCHI, Masaya

“…Many studies have suggested the involvement of multiple genetic loci in the development of systemic lupus erythematosus (SLE). We have analyzed the correlation…”
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RP105‐lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies by Kikuchi, Yuji, Koarada, Syuichi, Tada, Yoshifumi, Ushiyama, Osamu, Morito, Fumitaka, Suzuki, Noriaki, Ohta, Akihide, Miyake, Kensuke, Kimoto, Masao, Horiuchi, Takahiko, Nagasawa, Kohei

“…Objective We previously reported that B cells lacking the RP105 molecule, which proved to be highly activated B cells, are increased in the peripheral blood of…”
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Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism by Ryoko Sherriff-TadanoAkihide OhtaFumitaka MoritoMio MitamuraYoshio HarutaShuichi KoaradaYoshifumi TadaKohei NagasawaIwata Ozaki

“…We investigated the effect of hepatocyte growth factor (HGF) on collagen metabolism in cultured fibroblasts from scleroderma (SSc) patients and discussed the…”
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Role of the Costimulatory Molecule CD28 in the Development of Lupus in MRL/lpr Mice by Tada, Yoshifumi, Nagasawa, Kohei, Ho, Alexandra, Morito, Fumitaka, Koarada, Syuichi, Ushiyama, Osamu, Suzuki, Noriaki, Ohta, Akihide, Mak, Tak W

“…MRL/Mpj-lpr/lpr (MRL/lpr) mice develop autoimmune disorders, including lymphoproliferation, glomerulonephritis, autoantibody production, and…”
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Collagen-Induced Arthritis in TNF Receptor-1-Deficient Mice: TNF Receptor-2 Can Modulate Arthritis in the Absence of TNF Receptor-1 by Tada, Yoshifumi, Ho, Alexandra, Koarada, Syuichi, Morito, Fumitaka, Ushiyama, Osamu, Suzuki, Noriaki, Kikuchi, Yuji, Ohta, Akihide, Mak, Tak W., Nagasawa, Kohei

“…TNF is a potent proinflammatory cytokine important for the development of arthritis in human and animals. We have investigated the roles of TNF receptor-1…”
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Testosterone eliminates the attenuating effect of castration on the progressive glomerular injury in hypercholesterolemic male Imai rats by Sakemi, T, Toyoshima, H, Morito, F

“…Hypercholesterolemic Imai rats, especially males, spontaneously develop proteinuria and glomerulosclerosis. We have shown that castration attenuated the…”
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Sex difference in progression of adriamycin-induced nephropathy in rats by Sakemi, T, Ohtsuka, N, Tomiyoshi, Y, Morito, F

“…To clarify the pathogenesis of focal-segmental glomerulosclerosis, we investigated the sex-related difference and the effect of castration in Adriamycin (ADR)…”
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Effect of ovariectomy on glomerular injury in hypercholesterolemic female Imai rats by Sakemi, T, Ohtsuka, N, Shouno, Y, Morito, F

“…To clarify the pathogenesis of focal and segmental glomerulosclerosis, we investigated the effect of ovariectomy in hypercholesterolemic female Imai rats. At 5…”
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Estrogen attenuates progressive glomerular injury in hypercholesterolemic male Imai rats by Sakemi, T, Toyoshima, H, Shouno, Y, Morito, F

“…Hypercholesterolemic Imai rats spontaneously develop proteinuria and glomerulosclerosis, especially in males. A sex difference in glomerular injury has been…”
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The ovaries attenuate the aggravating effect of testosterone on glomerular injury in Adriamycin-induced nephropathy of female rats by Sakemi, T, Ohtsuka, N, Tomiyoshi, Y, Morito, F

“…To clarify whether the ovaries have a potential to attenuate the aggravating effect of testosterone (T) on glomerular injury, we investigated the effect of T…”
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Testosterone does not eliminate the attenuating effect of estrogen on progressive glomerular injury in estrogen-treated hypercholesterolemic male Imai rats by Sakemi, T, Ohtsuka, N, Tomiyoshi, Y, Morito, F

“…Hypercholesterolemic Imai rats spontaneously develop proteinuria and glomerulosclerosis, especially males. Estrogen attenuates the progressive glomerular…”
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Pharmacological effects of Dai-saiko-to on lipid biosynthesis in cultured human hepatocyte HepG 2 cells by Yamamoto, Kyosuke, Ogawa, Yoko, Yanagita, Teruyoshi, Morito, Fumitaka, Fukushima, Noriko, Ozaki, Iwata, Mizuta, Toshihiko, Setoguchi, Yoichi, Sakai, Takahiro

“…The pharmacological effects of Dai-saiko-to, a Japanese and Chinese traditional medicinal mixture (Kampohozai), on lipid biosynthesis were investigated in…”
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Ovariectomy attenuates proteinuria and glomerular injury in unilaterally nephrectomized female Sprague-Dawley rats by Sakemi, T, Ohtsuka, N, Shouno, Y, Morito, F

“…To determine the contribution of the ovary to the development of glomerulo-sclerosis, we investigated the effect of ovariectomy on glomerulosclerosis, using…”
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