Search Results - "Morita, Yuya"

Chemoselective Boron-Catalyzed Nucleophilic Activation of Carboxylic Acids for Mannich-Type Reactions by Morita, Yuya, Yamamoto, Tomohiro, Nagai, Hideoki, Shimizu, Yohei, Kanai, Motomu

“…The carboxyl group (COOH) is an omnipresent functional group in organic molecules, and its direct catalytic activation represents an attractive synthetic…”
Get full text

Ligand-Promoted, Boron-Mediated Chemoselective Carboxylic Acid Aldol Reaction by Nagai, Hideoki, Morita, Yuya, Shimizu, Yohei, Kanai, Motomu

“…The first carboxylic acid selective aldol reaction mediated by boron compounds and a mild organic base (DBU) was developed. Inclusion of electron-withdrawing…”
Get full text

Data-driven catalyst optimization for stereodivergent asymmetric synthesis by iridium/boron hybrid catalysis by Chen, Hongyu, Yamaguchi, Shigeru, Morita, Yuya, Nakao, Hiroyasu, Zhai, Xiangning, Shimizu, Yohei, Mitsunuma, Harunobu, Kanai, Motomu

“…Asymmetric catalysis enabling divergent control of multiple stereocenters remains challenging in synthetic organic chemistry. Although machine-learning-based…”
Get full text

Mobile parallel manipulator consisting of two nonholonomic carts and their path planning by YAO, Qiang, TERAKAWA, Tatsuro, MORITA, Yuya, KOMORI, Masaharu

“…Mobile manipulators are widely used to transport and manipulate objects in industrial settings. In this paper, we propose a mobile manipulator that consists of…”
Get full text

Blue-Shifting Mechanofluorochromic Luminescent Behavior of Polymer Composite Films Using Gelable Mechanoresponsive Compound by Kondo, Mizuho, Morita, Yuya, Kawatsuki, Nobuhiro

“…Mechanochromic luminescent dyes change their luminescence color upon exposure to external mechanical stimuli. In this study, we synthesized a liquid…”
Get full text

Intercalation-Controlled Cyclodehydration of Sorbitol in Water over Layered-Niobium-Molybdate Solid Acid by Morita, Yuya, Furusato, Shogo, Takagaki, Atsushi, Hayashi, Shigenobu, Kikuchi, Ryuji, Oyama, S. Ted

“…Layered niobium molybdate (HNbMoO6) was used in the aqueous‐phase dehydration of sorbitol and was found to exhibit remarkable selectivity toward its…”
Get full text

Dissolution behavior of core structure materials by molten corium in boiling water reactor plants during severe accidents by Sumita, Takehiro, Urata, Kentaro, Morita, Yuya, Kobayashi, Yoshinao

“…For the decommissioning of the Fukushima Daiichi Nuclear Power Plant, it is necessary to consider the access route to the fuel debris for its removal, which…”
Get full text

Reducer-integrated motor using simultaneous engagement of gear pairs with small and no differences in teeth number by Tatsuro TERAKAWA, Masaharu KOMORI, Shouta TAMURA, Ryo KATAOKA, Yuya MORITA

“…The motors for industrial robots and transporting robots require high-precision positioning, large torque output, and downsizing. However, conventional motors…”
Get full text

Age-dependent changes in the susceptibility to thiopental anesthesia in mice: Analysis of the relationship to the functional expression of GABA transporter by Sogawa, Norio, Hazehara, Yuri, Kunitomo, Muneyoshi, Morita, Yuya, Yoo, Bupsang, Ohyama, Kazumi, Sogawa, Chiharu, Kitayama, Shigeo

“…The potency of anesthetics changes during development, probably due not only to pharmacokinetic factors such as differential distribution and/or metabolism,…”
Get full text

Gait Phase Detection Using Foot Acceleration for Estimating Ground Reaction Force in Long Distance Gait Rehabilitation by Kawamura, Kazuya, Morita, Yuya, Okamoto, Jun, Saito, Kohei, Sessa, Salvatore, Zecca, Massimiliano, Takanishi, Atsuo, Takasugi, Shin-ichiro, Fujie, Masakatsu G.

“…In gait rehabilitation, achieving a gait analysis method using a simple system during long-distance walking is important. This method is required to measure…”
Get full text

Chemo- and Enantioselective Pd/B Hybrid Catalysis for the Construction of Acyclic Quaternary Carbons: Migratory Allylation of O‑Allyl Esters to α‑C‑Allyl Carboxylic Acids by Fujita, Taiki, Yamamoto, Tomohiro, Morita, Yuya, Chen, Hongyu, Shimizu, Yohei, Kanai, Motomu

“…We describe herein the asymmetric synthesis of α-allyl carboxylic acids containing an α-quaternary stereocenter by a chiral hybrid catalyst system comprising…”
Get full text

Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets by Ohta, Atsushi, Tanada, Mikimasa, Shinohara, Shojiro, Morita, Yuya, Nakano, Kazuhiko, Yamagishi, Yusuke, Takano, Ryusuke, Kariyuki, Shiori, Iida, Takeo, Matsuo, Atsushi, Ozeki, Kazuhisa, Emura, Takashi, Sakurai, Yuuji, Takano, Koji, Higashida, Atsuko, Kojima, Miki, Muraoka, Terushige, Takeyama, Ryuuichi, Kato, Tatsuya, Kimura, Kaori, Ogawa, Kotaro, Ohara, Kazuhiro, Tanaka, Shota, Kikuchi, Yasufumi, Hisada, Nozomi, Hayashi, Ryuji, Nishimura, Yoshikazu, Nomura, Kenichi, Tachibana, Tatsuhiko, Irie, Machiko, Kawada, Hatsuo, Torizawa, Takuya, Murao, Naoaki, Kotake, Tomoya, Tanaka, Masahiko, Ishikawa, Shiho, Miyake, Taiji, Tamiya, Minoru, Arai, Masako, Chiyoda, Aya, Akai, Sho, Sase, Hitoshi, Kuramoto, Shino, Ito, Toshiya, Shiraishi, Takuya, Kojima, Tetsuo, Iikura, Hitoshi

“…Establishing a technological platform for creating clinical compounds inhibiting intracellular protein–protein interactions (PPIs) can open the door to many…”
Get full text

Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display by Kage, Mirai, Hayashi, Ryuji, Matsuo, Atsushi, Tamiya, Minoru, Kuramoto, Shino, Ohara, Kazuhiro, Irie, Machiko, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Kotake, Tomoya, Takeyama, Ryuuichi, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Hashimoto, Satoshi, Kawada, Hatsuo, Nishimura, Yoshikazu, Nii, Keiji, Sase, Hitoshi, Ohta, Atsushi, Kojima, Tetsuo, Iikura, Hitoshi, Tanada, Mikimasa, Shiraishi, Takuya

“…[Display omitted] Cyclic peptides are attracting attention as therapeutic agents due to their potential for oral absorption and easy access to tough…”
Get full text

Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor by Tanada, Mikimasa, Tamiya, Minoru, Matsuo, Atsushi, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Irie, Machiko, Kotake, Tomoya, Takeyama, Ryuuichi, Kawada, Hatsuo, Hayashi, Ryuji, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Kage, Mirai, Hashimoto, Satoshi, Nii, Keiji, Sase, Hitoshi, Ohara, Kazuhiro, Ohta, Atsushi, Kuramoto, Shino, Nishimura, Yoshikazu, Iikura, Hitoshi, Shiraishi, Takuya

“…Cyclic peptides as a therapeutic modality are attracting a lot of attention due to their potential for oral absorption and accessibility to intracellular tough…”
Get full text