Search Results - "Morita, Tsuyoshi"

Regulation of Arp5 expression by alternative splicing coupled to nonsense-mediated RNA decay by Morita, Tsuyoshi, Hayashi, Ken'ichiro

“…Actin-related protein 5 (ARP5) inhibits the differentiation of skeletal, smooth, and cardiac muscle tissues, and ARP5 expression increases or decreases…”
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Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway by Morita, Tsuyoshi, Sobue, Kenji

“…Mammalian target of rapamycin (mTOR) is an important regulator of neuronal development and functions. Although it was reported recently that mTOR signaling is…”
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Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet by Raju, Resmi, Oshima, Masamitsu, Inoue, Miho, Morita, Tsuyoshi, Huijiao, Yan, Waskitho, Arief, Baba, Otto, Inoue, Masahisa, Matsuka, Yoshizo

“…Periodontal tissue is a distinctive tissue structure composed three-dimensionally of cementum, periodontal ligament (PDL) and alveolar bone. Severe periodontal…”
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Actin-related protein 5 functions as a novel modulator of MyoD and MyoG in skeletal muscle and in rhabdomyosarcoma by Morita, Tsuyoshi, Hayashi, Ken'ichiro

“…Myogenic regulatory factors (MRFs) are pivotal transcription factors in myogenic differentiation. MyoD commits cells to the skeletal muscle lineage by inducing…”
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Dual roles of myocardin-related transcription factors in epithelial-mesenchymal transition via slug induction and actin remodeling by Morita, Tsuyoshi, Mayanagi, Taira, Sobue, Kenji

“…Epithelial-mesenchymal transition (EMT) is a critical process occurring during embryonic development and in fibrosis and tumor progression. Dissociation of…”
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Model-based analysis uncovers mutations altering autophagy selectivity in human cancer by Han, Zhu, Zhang, Weizhi, Ning, Wanshan, Wang, Chenwei, Deng, Wankun, Li, Zhidan, Shang, Zehua, Shen, Xiaofei, Liu, Xiaohui, Baba, Otto, Morita, Tsuyoshi, Chen, Lu, Xue, Yu, Jia, Da

“…Autophagy can selectively target protein aggregates, pathogens, and dysfunctional organelles for the lysosomal degradation. Aberrant regulation of autophagy…”
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Actin‐related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2 by Morita, Tsuyoshi, Hayashi, Ken'ichiro

“…MYOCD is a transcription factor important for cardiac and smooth muscle development. We previously identified that actin‐related protein 5 (ARP5) binds to the…”
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Expression of secretory calcium-binding phosphoprotein (scpp) genes in medaka during the formation and replacement of pharyngeal teeth by Morita, Tsuyoshi, Matsumoto, Shin, Baba, Otto

“…Abstract Background Analyses of tooth families and tooth-forming units in medaka with regard to tooth replacement cycles and the localization of odontogenic…”
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RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling by Hayashi, Ken'ichiro, Watanabe, Bunta, Nakagawa, Yoshiaki, Minami, Saki, Morita, Tsuyoshi

“…Epithelial-msenchymal transition (EMT) is closely associated with cancer and tissue fibrosis. The nuclear accumulation of myocardin-related transcription…”
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Tumor Progression Is Mediated by Thymosin-β4 through a TGFβ/MRTF Signaling Axis by Morita, Tsuyoshi, Hayashi, Ken'ichiro

“…Although enhanced thymosin β4 (TMSB4X/Tβ4) expression is associated with tumor progression and metastasis, its tumor-promoting functions remain largely…”
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Arp5 is a key regulator of myocardin in smooth muscle cells by Morita, Tsuyoshi, Hayashi, Ken'ichiro

“…Myocardin (Myocd) and Myocd-related transcription factors (MRTFs) are robust coactivators of serum response factor (SRF). RPEL motifs are monomeric globular…”
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Ultrastructural characteristics of oligodendrocyte precursor cells in the early postnatal mouse optic nerve observed by serial block-face scanning electron microscopy by Ono, Katsuhiko, Gotoh, Hitoshi, Nomura, Tadashi, Morita, Tsuyoshi, Baba, Otto, Matsumoto, Mami, Saitoh, Sei, Ohno, Nobuhiko

“…Oligodendrocyte precursor cells (OPC) arise from restricted regions of the central nervous system (CNS) and differentiate into myelin-forming cells after…”
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Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption by Kano, Tsuyoshi, Morita, Tsuyoshi, Sumida, Kaori, Yumoto, Hiromichi, Baba, Otto

“…A previous study suggested that fibroblast growth factor (FGF) signaling plays an important role in dentin formation during tooth development. In this study,…”
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Differences in the Nuclear Export Mechanism between Myocardin and Myocardin-related Transcription Factor A by Hayashi, Ken'ichiro, Morita, Tsuyoshi

“…Myocardin (Mycd), a key factor in smooth muscle cell differentiation, is constitutively located in the nucleus, whereas myocardin-related transcription factors…”
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Ultrastructural characteristics of oligodendrocyte precursor cells in the early postnatal mouse optic nerve observed by serial block-face scanning electron microscopy by Katsuhiko Ono, Hitoshi Gotoh, Tadashi Nomura, Tsuyoshi Morita, Otto Baba, Mami Matsumoto, Sei Saitoh, Nobuhiko Ohno

“…Oligodendrocyte precursor cells (OPC) arise from restricted regions of the central nervous system (CNS) and differentiate into myelin-forming cells after…”
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Significance of the p38MAPK-CRP2 axis in myofibroblastic phenotypic transition by Hayashi, Ken’ichiro, Labios, Reuben Jacob, Morita, Tsuyoshi, Ashimori, Atsushige, Aoki, Ren, Mikuni, Masanori, Kimura, Kazuhiro

“…We have recently demonstrated that a LIM domain protein, cysteine and glycine-rich protein 2 (CSRP2 [CRP2]), plays a vital role in the functional expression of…”
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Role of CRP2-MRTF interaction in functions of myofibroblasts by Hayashi, Ken’ichiro, Horoiwa, Shinri, Mori, Kotaro, Miyata, Hiroshi, Labios, Reuben Jacob, Morita, Tsuyoshi, Kobayashi, Yuka, Yamashiro, Chiemi, Higashijima, Fumiaki, Yoshimoto, Takuya, Kimura, Kazuhiro, Nakagawa, Yoshiaki

“…Inflammatory response induces phenotypic modulation of fibroblasts into myofibroblasts. Although transforming growth factor-βs (TGF-βs) evoke such transition,…”
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A vision-based road detection system for the navigation of an agricultural autonomous tractor by SAHA, Sristi, MORITA, Tsuyoshi, NOGUCHI, Noboru

“…Autonomous tractors can operate in open fields by using the RTK-GNSS (Real-time Kinematic-Global Navigation Satellite System). However, RTK-GNSS signal might…”
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G-actin sequestering protein thymosin-β4 regulates the activity of myocardin-related transcription factor by Morita, Tsuyoshi, Hayashi, Ken’ichiro

“…•Tβ4 competed with MRTF-A for G-actin binding.•Tβ4 activated the MRTF–SRF signaling pathway.•Tβ4 increased the endogenous expression of SRF-dependent genes…”
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Radical Cyclizations of Aryl Bromides for Synthesis of Cyclopenta[b]indoles from Vince Lactam by Abe, Takumi, Morita, Tsuyoshi, Yamada, Koji

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