Search Results - "Morita, Shuhei"

Distinct clinical features and prognosis between persistent and temporary thyroid dysfunctions by immune-checkpoint inhibitors by Inaba, Hidefumi, Ariyasu, Hiroyuki, Iwakura, Hiroshi, Kurimoto, Chiaki, Takeshima, Ken, Morita, Shuhei, Furuta, Hiroto, Hotomi, Muneki, Akamizu, Takashi

“…Immune-related adverse events in the thyroid glands (thyroid irAEs) during treatment with immune-checkpoint inhibitors (ICIs) are most frequent endocrine irAE…”
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Predictive and sensitive biomarkers for thyroid dysfunctions during treatment with immune‐checkpoint inhibitors by Kurimoto, Chiaki, Inaba, Hidefumi, Ariyasu, Hiroyuki, Iwakura, Hiroshi, Ueda, Yoko, Uraki, Shinsuke, Takeshima, Ken, Furukawa, Yasushi, Morita, Shuhei, Yamamoto, Yuki, Yamashita, Shimpei, Katsuda, Masahiro, Hayata, Atsushi, Akamatsu, Hiroaki, Jinnin, Masatoshi, Hara, Isao, Yamaue, Hiroki, Akamizu, Takashi

“…Immune‐related adverse events (irAEs) are often seen during immune‐checkpoint inhibitor (ICI) treatment of various malignancies. Endocrine irAEs including…”
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Renoprotective potential of concomittant medications with SGLT2 inhibitors and renin-angiotensin system inhibitors in diabetic nephropathy without albuminuria: a retrospective cohort study by Ishibashi, Tatsuya, Morita, Shuhei, Furuta, Hiroto, Nishi, Masahiro, Matsuoka, Taka-Aki

“…The renal protective effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors and renin-angiotensin system (RAS) inhibitors on diabetic nephropathy…”
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Quantification of serum C-mannosyl tryptophan by novel assay to evaluate renal function and vascular complications in patients with type 2 diabetes by Morita, Shuhei, Inai, Yoko, Minakata, Shiho, Kishimoto, Shohei, Manabe, Shino, Iwahashi, Naoyuki, Ino, Kazuhiko, Ito, Yukishige, Akamizu, Takashi, Ihara, Yoshito

“…C -Mannosyl tryptophan (CMW) is a unique glycosylated amino acid, and a candidate novel biomarker of renal function. In type 2 diabetes (T2D), a combination of…”
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The influence of thyroid autoimmunity on pregnancy outcome in infertile women: a prospective study by Inagaki, Yuko, Takeshima, Ken, Nishi, Masahiro, Ariyasu, Hiroyuki, Doi, Asako, Kurimoto, Chiaki, Uraki, Shinsuke, Morita, Shuhei, Furukawa, Yasushi, Inaba, Hidefumi, Iwakura, Hiroshi, Shimokawa, Toshio, Utsunomiya, Tomoko, Akamizu, Takashi

“…Thyroid dysfunction and thyroid autoimmunity (TAI) have been reported to be linked to infertility, pregnancy loss and preterm birth. Infertile women undergoing…”
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Possible contribution of COVID-19 vaccination to the subsequent mental well-being in Japan by Chiang, Chifa, Morita, Shuhei, Hirakawa, Yoshihisa, Priya, Farzana Tanzin, Matsumoto, Yuka, Ota, Atsuhiko, Yatsuya, Hiroshi, Tabuchi, Takahiro

“…The coronavirus disease 2019 (COVID-19) pandemic has had a severe impact on mental well-being. Vaccination may have played a pivotal role in enduring this…”
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Pheochromocytoma Multisystem Crisis Complicated by Severe Acute Pancreatitis by Inaba, Hidefumi, Kaido, Yosuke, Kosugi, Daisuke, Asai, Yuki, Ogino, Shinya, Nakano, Shogo, Ito, Saya, Hirobata, Tomonao, Ono, Kazuo, Minaga, Kosuke, Morita, Shuhei, Inoue, Gen

“…A 43-year-old man developed headache, dizziness, abdominal pain, and vomiting. His blood pressure was 203/121 mmHg, heart rate 122 beats/min, body temperature…”
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C-Mannosyl tryptophan is a novel biomarker for thrombocytosis of myeloproliferative neoplasms by Tabata, Shotaro, Yamashita, Yusuke, Inai, Yoko, Morita, Shuhei, Kosako, Hideki, Takagi, Tomoyuki, Shide, Kotaro, Manabe, Shino, Matsuoka, Taka-aki, Shimoda, Kazuya, Sonoki, Takashi, Ihara, Yoshito, Tamura, Shinobu

“…C -Mannosyl tryptophan (CMW), a unique glycosylated amino acid, is considered to be produced by degradation of C -mannosylated proteins in living organism…”
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Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma by Kosako, Hideki, Yamashita, Yusuke, Morita, Shuhei, Iwabuchi, Sadahiro, Hashimoto, Shinichi, Matsuoka, Taka-Aki, Sonoki, Takashi, Tamura, Shinobu

“…Endoplasmic reticulum stress activates inositol-requiring enzyme 1α (IRE1α) and protein kinase, R-like endoplasmic reticulum kinase (PERK), the two principal…”
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Comparative analysis of human leucocyte antigen between idiopathic and anti‐PD‐1 antibody induced isolated adrenocorticotropic hormone deficiency: A pilot study by Inaba, Hidefumi, Ariyasu, Hiroyuki, Iwakura, Hiroshi, Ueda, Yoko, Kurimoto, Chiaki, Uraki, Shinsuke, Takeshima, Ken, Yamaoka, Hiroyuki, Furukawa, Yasushi, Morita, Shuhei, Nishi, Masahiro, Akamizu, Takashi

“…Background Adult‐onset idiopathic isolated adrenocorticotropic hormone deficiency (id‐IAD) is a rare disease with unknown aetiology. Recently, numerous cases…”
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Isolated ACTH deficiency following immunization with the BNT162b2 SARS-CoV-2 vaccine: a case report by Morita, Shuhei, Tsuji, Tomoya, Kishimoto, Shohei, Uraki, Shinsuke, Takeshima, Ken, Iwakura, Hiroshi, Furuta, Hiroto, Nishi, Masahiro, Inaba, Hidefumi, Matsuoka, Taka-aki

“…Abstract Background The global COVID-19 pandemic requires urgent development of new vaccines. Endocrinological adverse effects following the new mRNA vaccine…”
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False-positive staining of thyroglobulin distinguished from mixed medullary and follicular thyroid carcinoma by duplex in situ hybridization by Takeshima, Ken, Ariyasu, Hiroyuki, Uraki, Shinsuke, Morita, Shuhei, Furukawa, Yasushi, Inaba, Hidefumi, Iwakura, Hiroshi, Doi, Asako, Warigaya, Kenji, Murata, Shin-ichi, Enomoto, Keisuke, Hotomi, Muneki, Akamizu, Takashi

“…Medullary thyroid carcinoma (MTC) may mimic mixed medullary and follicular thyroid carcinoma (MMFTC). MTC originates from para-follicular cells, while MMFTC is…”
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MSH6/2 and PD-L1 Expressions Are Associated with Tumor Growth and Invasiveness in Silent Pituitary Adenoma Subtypes by Uraki, Shinsuke, Ariyasu, Hiroyuki, Doi, Asako, Takeshima, Ken, Morita, Shuhei, Inaba, Hidefumi, Furuta, Hiroto, Fukuhara, Noriaki, Inoshita, Naoko, Nishioka, Hiroshi, Nakao, Naoyuki, Yamada, Shozo, Akamizu, Takashi

“…Mismatch repair genes ( ) expressions are involved in tumor growth and ( ) expression in tumor immunity, but the direct association with pituitary adenomas…”
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Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice by Ueda, Yoko, Iwakura, Hiroshi, Bando, Mika, Doi, Asako, Ariyasu, Hiroyuki, Inaba, Hidefumi, Morita, Shuhei, Akamizu, Takashi

“…Tryptophan is reportedly the most potent agonist for GPR142. Glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells are enhanced by…”
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Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR–Chk1 Pathway by Uraki, Shinsuke, Ariyasu, Hiroyuki, Doi, Asako, Kawai, Shintaro, Takeshima, Ken, Morita, Shuhei, Fukai, Junya, Fujita, Koji, Furuta, Hiroto, Nishi, Masahiro, Sugano, Kokichi, Inoshita, Naoko, Nakao, Naoyuki, Yamada, Shozo, Akamizu, Takashi

“…The mechanisms of pituitary adenoma (PA) pathogenesis and proliferation remain largely unknown. To evaluate the direct association between PA proliferation and…”
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A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages by Sasaki, Izumi, Fukuda-Ohta, Yuri, Nakai, Chihiro, Wakaki-Nishiyama, Naoko, Okamoto, Chizuyo, Okuzaki, Daisuke, Morita, Shuhei, Kaji, Shiori, Furuta, Yuki, Hemmi, Hiroaki, Kato, Takashi, Yamamoto, Asumi, Tosuji, Emi, Saitoh, Shin-Ichiroh, Tanaka, Takashi, Hoshino, Katsuaki, Fukuda, Shinji, Miyake, Kensuke, Kuroda, Etsushi, Ishii, Ken J., Iwawaki, Takao, Furukawa, Koichi, Kaisho, Tsuneyasu

“…Cholera toxin (CT), a bacterial exotoxin composed of one A subunit (CTA) and five B subunits (CTB), functions as an immune adjuvant. CTB can induce production…”
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Head and Neck Paraganglioma Atypically Carrying a Succinate Dehydrogenase Subunit B Mutation (L157X) by Takeshima, Ken, Ariyasu, Hiroyuki, Uraki, Shinsuke, Kitahara, Chie, Morita, Shuhei, Inaba, Hidefumi, Iwakura, Hiroshi, Warigaya, Kenji, Murata, Shin-ichi, Yamazaki, Yuto, Sasano, Hironobu, Akamizu, Takashi

“…A 53-year-old woman was admitted to a hospital for gradual left-ear hearing loss over 2 years. Head computed tomography revealed a 2-cm mass along the left…”
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Validation of Efficacy and Safety of TachoSil® Tissue Sealant for Vessel Transposition in Microvascular Decompression by Mori, Kentaro, Otani, Naoki, Toyooka, Terushige, Morita, Shuhei, Numazawa, Shinichi, Wada, Kojiro, Watanabe, Sadayoshi

“…BACKGROUND AND OBJECTIVES: Use of TachoSil ® as the transposition material of microvascular decompression (MVD) for hemifacial spasm (HFS) and trigeminal…”
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Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib by Yamashita, Yusuke, Morita, Shuhei, Hosoi, Hiroki, Kobata, Hiroshi, Kishimoto, Shohei, Ishibashi, Tatsuya, Mishima, Hiroyuki, Kinoshita, Akira, Backes, Bradley J, Yoshiura, Koh-Ichiro, Papa, Feroz R, Sonoki, Takashi, Tamura, Shinobu

“…Inositol-requiring enzyme 1α (IRE1α), along with protein kinase R-like endoplasmic reticulum kinase (PERK), is a principal regulator of the unfolded protein…”
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Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors by Inaba, Hidefumi, Morita, Shuhei, Kosugi, Daisuke, Asai, Yuki, Kaido, Yosuke, Ito, Saya, Hirobata, Tomonao, Inoue, Gen, Yamamoto, Yuki, Jinnin, Masatoshi, Kimura, Hiroaki, Ota, Masao, Okudaira, Yuko, Nakatani, Hiroyasu, Kobayashi, Tomoko, Iwama, Shintaro, Arima, Hiroshi, Matsuoka, Takaaki

“…Immune-checkpoint inhibitors are effective in various advanced cancers. Type 1 diabetes mellitus induced by them (ICI-T1DM) is a serious complication requiring…”
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