Search Results - "Morissette, P"

Patient-Specific Alterations in CO2 Cerebrovascular Responsiveness in Acute and Sub-Acute Sports-Related Concussion by Mutch, W. Alan C., Ellis, Michael J., Ryner, Lawrence N., McDonald, Patrick J., Morissette, Marc P., Pries, Philip, Essig, Marco, Mikulis, David J., Duffin, James, Fisher, Joseph A.

“…BACKGROUNDPreliminary studies suggest that sports-related concussion (SRC) is associated with alterations in cerebral blood flow (CBF) regulation. Here, we use…”
Get full text

Shortening of the electromechanical window in the ketamine/xylazine-anesthetized guinea pig model to assess pro-arrhythmic risk in early drug development by Morissette, P., Regan, C., Fitzgerald, K., Gerenser, P., Travis, J., Wang, S., Fanelli, P., Sannajust, F.

“…A negative electromechanical window (EMw) was recently proposed as a better preclinical tool than QTc interval to predict clinical pro-arrhythmic potential. As…”
Get full text

Differential regulation of the fiber type-specific gene expression of the sarcoplasmic reticulum calcium-ATPase isoforms induced by exercise training by Morissette, Marc P, Susser, Shanel E, Stammers, Andrew N, O'Hara, Kimberley A, Gardiner, Phillip F, Sheppard, Patricia, Moffatt, Teri L, Duhamel, Todd A

“…The regulatory role of adenosine monophosphate-activated protein kinase (AMPK)-α2 on sarcoplasmic reticulum calcium-ATPase (SERCA) 1a and SERCA2a in different…”
Get full text

Associations between concussion and risk of diagnosis of psychological and neurological disorders: a retrospective population-based cohort study by Morissette, Marc P, Prior, Heather J, Tate, Robert B, Wade, John, Leiter, Jeff R S

“…ObjectiveTo investigate associations between concussion and the risk of follow-up diagnoses of attention-deficit hyperactivity disorder (ADHD), mood and…”
Get full text

Inter‐study variability of preclinical in vivo safety studies and translational exposure–QTc relationships – a PKPD meta‐analysis by Gotta, V, Cools, F, Ammel, K, Gallacher, D J, Visser, S A G, Sannajust, F, Morissette, P, Danhof, M, Graaf, P H

“…Background and Purpose Preclinical cardiovascular safety studies (CVS) have been compared between facilities with respect to their sensitivity to detect…”
Get full text

Evaluation of Early Submaximal Exercise Tolerance in Adolescents with Symptomatic Sport-related Concussion by MORISSETTE, MARC P., CORDINGLEY, DEAN M., ELLIS, MICHAEL J., LEITER, JEFF R. S.

“…PURPOSEThis study aimed to compare cardiorespiratory response to a graded aerobic exercise challenge between adolescents with symptomatic sport-related…”
Get full text

Graded Aerobic Treadmill Testing in Adolescent Traumatic Brain Injury Patients by Cordingley, Dean M, Girardin, Richard, Morissette, Marc P, Reimer, Karen, Leiter, Jeff, Russell, Kelly, Ellis, Michael J

“…To examine the safety and tolerability of clinical graded aerobic treadmill testing in recovering adolescent moderate and severe traumatic brain injury (TBI)…”
Get more information

Postoperative recovery comparisons of arthroscopic Bankart to open Latarjet for the treatment of anterior glenohumeral instability by Woodmass, Jarret M., Wagner, Eric R., Smith, Jennifer, Welp, Kathryn M., Chang, Michelle J., Morissette, Marc P., Higgins, Laurence D., Warner, Jon J. P.

“…Background Recurrent anterior glenohumeral instability is a disabling pathology that can be successfully treated by arthroscopic Bankart repair or open…”
Get full text

Exercise-induced increases in the expression and activity of cardiac sarcoplasmic reticulum calcium ATPase 2 is attenuated in AMPKα 2 kinase-dead mice by Morissette, Marc P, Susser, Shanel E, Stammers, Andrew N, Moffatt, Teri L, Wigle, Jeffrey T, Wigle, Theodore J, Netticadan, Thomas, Premecz, Sheena, Jassal, Davinder S, O'Hara, Kimberley A, Duhamel, Todd A

“…Exercise enhances cardiac sarcoplasmic reticulum Ca -ATPase 2a (SERCA2a) function through unknown mechanisms. The present study tested the hypothesis that the…”
Get more information

Longitudinal Brain Magnetic Resonance Imaging CO2 Stress Testing in Individual Adolescent Sports-Related Concussion Patients: A Pilot Study by Mutch, W Alan C, Ellis, Michael J, Ryner, Lawrence N, Morissette, Marc P, Pries, Philip J, Dufault, Brenden, Essig, Marco, Mikulis, David J, Duffin, James, Fisher, Joseph A

“…Advanced neuroimaging studies in concussion have been limited to detecting group differences between concussion patients and healthy controls. In this small…”
Get full text

Partial Rotator Cuff Repair Provides Improved Patient-Reported Outcome Measures Following Superior Capsule Reconstruction (SCR) by Woodmass, Jarret M., Wagner, Eric R., Welp, Kathryn M., Chang, Michelle J., Morissette, Marc P., Higgins, Laurence D., Warner, Jon J.P.

“…To evaluate the role of concomitant partial rotator cuff repair (RCR) (i.e., infraspinatus) on patient-reported clinical outcomes following superior capsule…”
Get full text

Exercise training prevents the development of cardiac dysfunction in the low-dose streptozotocin diabetic rats fed a high-fat diet by Epp, Riley A, Susser, Shanel E, Morissette, Marc P, Kehler, D Scott, Jassal, Davinder S, Duhamel, Todd A

“…This study tested the hypothesis that exercise training would prevent the development of diabetes-induced cardiac dysfunction and altered expression of…”
Get more information

The Effects of Acute Anaerobic Exercise on the Cardiovascular and Metabolic Response to the Cold Pressor Test in Healthy Adult Males by Morissette, Marc P, Cordingley, Dean M, Duhamel, Todd A, Leiter, Jeff R S

“…Little is known about the physiological response to the cold pressor test (CPT) when in a clinically-induced state of autonomic nervous system (ANS) imbalance,…”
Get full text

Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry by Lagrutta, Armando, Regan, Christopher P., Zeng, Haoyu, Imredy, John P., Koeplinger, Kenneth, Morissette, Pierre, Liu, Liping, Wollenberg, Gordon, Brynczka, Christopher, Lebrón, José, DeGeorge, Joseph, Sannajust, Frederick

“…Severe bradycardia/bradyarrhythmia following coadministration of the HCV-NS5B prodrug sofosbuvir with amiodarone was recently reported. Our previous…”
Get full text

Colloid osmotic pressure: its measurement and clinical value by Morissette, M. P

“…Plasma colloid osmotic pressure (COP) is an important determinant in the appearance of edema. The development of a simple technique for COP measurement, based…”
Get full text

Drug-induced long QT syndrome and torsade de pointes by Morissette, Pierre, Hreiche, Raymond, Turgeon, Jacques

“…Several medications, including drugs prescribed for noncardiac indications, have been associated with a prolongation of the QT interval on the surface…”
Get more information

In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetil by MORISSETTE, Pierre, ALBERT, Caroline, BUSQUE, Stephan, ST-LOUIS, Gilles, VINET, Bernard

“…Mycophenolate mofetil (MMF), an immunosuppressant drug used in organ transplantation to prevent rejection, is being used increasingly in association with…”
Get full text

Social Network Normative Influence and Sexual Risk-Taking Among Women Seeking a New Partner by Dedobbeleer, Nicole, Morissette, Pauline, Rojas-Viger, Célia

“…This paper examines the relative influence of social network norms on sexual risk-taking among women seeking a new partner in Quebec (Canada). A survey was…”
Get full text

Patient-Specific Alterations in CO 2 Cerebrovascular Responsiveness in Acute and Sub-Acute Sports-Related Concussion by Mutch, W Alan C, Ellis, Michael J, Ryner, Lawrence N, McDonald, Patrick J, Morissette, Marc P, Pries, Philip, Essig, Marco, Mikulis, David J, Duffin, James, Fisher, Joseph A

“…Preliminary studies suggest that sports-related concussion (SRC) is associated with alterations in cerebral blood flow (CBF) regulation. Here, we use advanced…”
Get full text

A specific artificial antibody toward mycophenolic acid prepared by molecular imprinting by Morissette, P, Beaulieu, M, Vinet, B

Get full text