Search Results - "Morisset, Ludivine"

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities by Pancholi, Sunil, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Nikitorowicz-Buniak, Joanna, Ressa, Anna, Gao, Qiong, Leal, Mariana Ferreira, Bhamra, Amandeep, Thornhill, Allan, Morisset, Ludivine, Montaudon, Elodie, Sourd, Laura, Fitzpatrick, Martin, Altelaar, Maarten, Johnston, Stephen R., Marangoni, Elisabetta, Dowsett, Mitch, Martin, Lesley-Ann

“…Combination of CDK4/6 inhibitors and endocrine therapy improves clinical outcome in advanced oestrogen receptor (ER)-positive breast cancer, however relapse is…”
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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance by Montaudon, Elodie, Nikitorowicz-Buniak, Joanna, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Huguet, Léa, Dahmani, Ahmed, Painsec, Pierre, Nemati, Fariba, Vacher, Sophie, Chemlali, Walid, Masliah-Planchon, Julien, Château-Joubert, Sophie, Rega, Camilla, Leal, Mariana Ferreira, Simigdala, Nikiana, Pancholi, Sunil, Ribas, Ricardo, Nicolas, André, Meseure, Didier, Vincent-Salomon, Anne, Reyes, Cécile, Rapinat, Audrey, Gentien, David, Larcher, Thibaut, Bohec, Mylène, Baulande, Sylvain, Bernard, Virginie, Decaudin, Didier, Coussy, Florence, Le Romancer, Muriel, Dutertre, Guillaume, Tariq, Zakia, Cottu, Paul, Driouch, Keltouma, Bièche, Ivan, Martin, Lesley-Ann, Marangoni, Elisabetta

“…A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with…”
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BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers by Coussy, Florence, El-Botty, Rania, Château-Joubert, Sophie, Dahmani, Ahmed, Montaudon, Elodie, Leboucher, Sophie, Morisset, Ludivine, Painsec, Pierre, Sourd, Laura, Huguet, Léa, Nemati, Fariba, Servely, Jean-Luc, Larcher, Thibaut, Vacher, Sophie, Briaux, Adrien, Reyes, Cécile, La Rosa, Philippe, Lucotte, Georges, Popova, Tatiana, Foidart, Pierre, Sounni, Nor Eddine, Noel, Agnès, Decaudin, Didier, Fuhrmann, Laetitia, Salomon, Anne, Reyal, Fabien, Mueller, Christopher, Ter Brugge, Petra, Jonkers, Jos, Poupon, Marie-France, Stern, Marc-Henri, Bièche, Ivan, Pommier, Yves, Marangoni, Elisabetta

“…Topoisomerase I (TOP1) inhibitors trap TOP1 cleavage complexes resulting in DNA double-strand breaks (DSBs) during replication, which are repaired by…”
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Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer by Simões, Bruno M., Santiago-Gómez, Angélica, Chiodo, Chiara, Moreira, Tiago, Conole, Daniel, Lovell, Scott, Alferez, Denis, Eyre, Rachel, Spence, Katherine, Sarmiento-Castro, Aida, Kohler, Bertram, Morisset, Ludivine, Lanzino, Marilena, Andò, Sebastiano, Marangoni, Elisabetta, Sims, Andrew H., Tate, Edward W., Howell, Sacha J., Clarke, Robert B.

“…Estrogen receptor (ER) positive breast cancer is frequently sensitive to endocrine therapy. Multiple mechanisms of endocrine therapy resistance have been…”
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Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers by ter Brugge, Petra, Moser, Sarah C., Bièche, Ivan, Kristel, Petra, Ibadioune, Sabrina, Eeckhoutte, Alexandre, de Bruijn, Roebi, van der Burg, Eline, Lutz, Catrin, Annunziato, Stefano, de Ruiter, Julian, Masliah Planchon, Julien, Vacher, Sophie, Courtois, Laura, El-Botty, Rania, Dahmani, Ahmed, Montaudon, Elodie, Morisset, Ludivine, Sourd, Laura, Huguet, Léa, Derrien, Heloise, Nemati, Fariba, Chateau-Joubert, Sophie, Larcher, Thibaut, Salomon, Anne, Decaudin, Didier, Reyal, Fabien, Coussy, Florence, Popova, Tatiana, Wesseling, Jelle, Stern, Marc-Henri, Jonkers, Jos, Marangoni, Elisabetta

“…The high frequency of homologous recombination deficiency (HRD) is the main rationale of testing platinum-based chemotherapy in triple-negative breast cancer…”
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A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer by Coussy, Florence, Koning, Leanne, Lavigne, Marion, Bernard, Virginie, Ouine, Berengere, Boulai, Anais, El Botty, Rania, Dahmani, Ahmed, Montaudon, Elodie, Assayag, Franck, Morisset, Ludivine, Huguet, Lea, Sourd, Laura, Painsec, Pierre, Callens, Celine, Chateau‐Joubert, Sophie, Servely, Jean‐Luc, Larcher, Thibaut, Reyes, Cecile, Girard, Elodie, Pierron, Gaelle, Laurent, Cecile, Vacher, Sophie, Baulande, Sylvain, Melaabi, Samia, Vincent‐Salomon, Anne, Gentien, David, Dieras, Veronique, Bieche, Ivan, Marangoni, Elisabetta

“…Triple‐negative breast cancer (TNBC) represents 10% of all breast cancers and is a very heterogeneous disease. Globally, women with TNBC have a poor prognosis,…”
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Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant by Jacquemetton, Julien, Kassem, Loay, Poulard, Coralie, Dahmani, Ahmed, De Plater, Ludmilla, Montaudon, Elodie, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Chateau-Joubert, Sophie, Vacher, Sophie, Bièche, Ivan, Treilleux, Isabelle, Trédan, Olivier, Marangoni, Elisabetta, Le Romancer, Muriel

“…Endocrine therapies targeting estrogen signaling have significantly improved breast cancer (BC) patient survival, although 40% of ERα-positive BCs do not…”
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Podocin Inactivation in Mature Kidneys Causes Focal Segmental Glomerulosclerosis and Nephrotic Syndrome by MOLLET, Géraldine, RATELADE, Julien, GUBLER, Marie-Claire, ANTIGNAC, Corinne, ESQUIVEL, Ernie L, BOYER, Olivia, ONETTI MUDA, Andrea, MORISSET, Ludivine, AGUIRRE LAVIN, Tiphaine, KITZIS, David, DALLMAN, Margaret J, BUGEON, Laurence, HUBNER, Norbert

“…Podocin is a critical component of the glomerular slit diaphragm, and genetic mutations lead to both familial and sporadic forms of steroid-resistant nephrotic…”
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Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers by Soosainathan, Arany, Iravani, Marjan, El-Botty, Rania, Alexander, John, Sourd, Laura, Morisset, Ludivine, Painsec, Pierre, Orha, Rebecca, Nikitorowicz-Buniak, Joanna, Pancholi, Sunil, Haider, Syed, Dowsett, Mitch, Marangoni, Elisabetta, Martin, Lesley-Ann, Isacke, Clare M

“…The combination of endocrine therapy and CDK4/6 inhibitors such as palbociclib is an effective and well-tolerated treatment for estrogen receptor-positive…”
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Renal phenotype of the cystinosis mouse model is dependent upon genetic background by Nevo, Nathalie, Chol, Marie, Bailleux, Anne, Kalatzis, Vasiliki, Morisset, Ludivine, Devuyst, Olivier, Gubler, Marie-Claire, Antignac, Corinne

“…Background. Cystinosis is caused by mutations in CTNS that encodes cystinosin, the lysosomal cystine transporter. The most severe and frequent form is…”
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Maternal Environment Interacts with Modifier Genes to Influence Progression of Nephrotic Syndrome by RATELADE, Julien, AGUIRRE LAVIN, Tiphaine, THERY, Clotilde, GUBLER, Marie-Claire, MONTAGUTELLI, Xavier, ANTIGNAC, Corinne, ESQUIVEL, Ernie L, ONETTI MUDA, Andrea, MORISSET, Ludivine, MOLLET, Géraldine, BOYER, Olivia, CHEN, Deborah S, HENGER, Anna, KRETZLER, Matthias, HUBNER, Norbert

“…Mutations in the NPHS2 gene, which encodes podocin, are responsible for some cases of sporadic and familial autosomal recessive steroid-resistant nephrotic…”
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