Search Results - "Morishita, Yohei"

The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi by Morishita, Yohei, Zhang, Huiping, Taniguchi, Tohru, Mori, Keiji, Asai, Teigo

“…Heterologous expression of a unique biosynthetic gene cluster (BGC) comprising a highly reducing polyketide synthase and stand-alone thioesterase genes in…”
Get full text

Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii by Morishita, Yohei, Tsukada, Kento, Murakami, Kazuma, Irie, Kazuhiro, Asai, Teigo

“…Diterpenoid pyrones are a type of mainly fungal meroterpenoid metabolite consisting of a diterpene connected to a pyrone, some of which show potent…”
Get full text

Post-genomic approach based discovery of alkylresorcinols from a cricket-associated fungus, Penicillium soppi by Kaneko, Akiho, Morishita, Yohei, Tsukada, Kento, Taniguchi, Tohru, Asai, Teigo

“…Polyketide synthase (PKS) gene-guided genome mining in a cricket-associated fungus, Penicillium soppi, revealed a cryptic biosynthetic gene cluster that…”
Get more information

Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach by Homma, Yuto, Sugawara, Akihiro, Morishita, Yohei, Tsukada, Kento, Ozaki, Taro, Asai, Teigo

“…Genome mining and bioinformatics analyses allowed us to rationally find a candidate biosynthetic gene cluster for a new cyclic depsipeptide of Chaetomium…”
Get full text

Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase by Furumura, Sho, Ozaki, Taro, Sugawara, Akihiro, Morishita, Yohei, Tsukada, Kento, Ikuta, Tatsuya, Inoue, Asuka, Asai, Teigo

“…By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation–thiolation didomain, which catalyzes the…”
Get full text

Genome mining of labdane-related diterpenoids: Discovery of the two-enzyme pathway leading to (-)-sandaracopimaradiene in the fungus Arthrinium sacchari by Sato, Fumito, Sonohara, Terutaka, Fujiki, Shunta, Sugawara, Akihiro, Morishita, Yohei, Ozaki, Taro, Asai, Teigo

“…Labdane-related diterpenoids (LRDs) in fungi are a pharmaceutically important, but underexplored family of natural products. In the biosynthesis of fungal…”
Get full text

Genome Mining-Based Discovery of Fungal Macrolides Modified by glycosylphosphatidylinositol (GPI)–Ethanolamine Phosphate Transferase Homologues by Morishita, Yohei, Aoki, Yu, Ito, Mei, Hagiwara, Daisuke, Torimaru, Kensho, Morita, Daichi, Kuroda, Teruo, Fukano, Hanako, Hoshino, Yoshihiko, Suzuki, Masato, Taniguchi, Tohru, Mori, Keiji, Asai, Teigo

“…Through genome mining for fungal macrolide natural products, we discovered a characteristic family of putative macrolide biosynthetic gene clusters that…”
Get full text

A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution by Fuchs, Sebastian W., Lackner, Gerald, Morinaka, Brandon I., Morishita, Yohei, Asai, Teigo, Riniker, Sereina, Piel, Jörn

“…Ribosomally synthesized and posttranslationally modified peptide natural products (RiPPs) exhibit diverse structures and bioactivities and are classified into…”
Get full text

High diagnostic accuracy for lymph node metastasis of oral squamous cell carcinoma using PET/CT with a silicon photomultiplier by Kojima, Ikuho, Takanami, Kentaro, Ogawa, Takenori, Ishikawa, Kenichiro, Morishita, Yohei, Ishii, Ryo, Ohkoshi, Akira, Nakanome, Ayako, Odagiri, Hayato, Iikubo, Masahiro

“…Objective The higher sensitivity of the new-generation positron emission tomography/computed tomography (PET/CT) with silicon photomultiplier (SiPM) may…”
Get full text

Preoperative Endovascular Embolization in an Easily Bleeding Respiratory Epithelial Adenomatoid Hamartoma of the Olfactory Cleft: A Case Report by Suzuki, Jun, Tozuka, Hiroki, Hemmi, Tomotaka, Ikushima, Hiroyuki, Ishikawa, Tomohiko, Morishita, Yohei, Nomura, Kazuhiro, Sugawara, Mitsuru, Katori, Yukio

“…Respiratory epithelial adenomatoid hamartomas (REAHs) are rare tumors occurring in the nasal cavity and sinuses, and their etiology is unknown. REAH is a…”
Get full text

Human papillomavirus-related multiphenotypic sinonasal carcinoma by Morishita, Yohei, Sakashita, Shingo, Tomioka, Toshifumi, Okano, Wataru, Shinozaki, Takeshi, Higashino, Takuya, Matsuura, Kazuto, Hayashi, Ryuichi

“…Human papillomavirus-related multiphenotypic sinonasal carcinoma (HMSC) is a rare primary tumor of the sinonasal tract that has been reported recently. It is…”
Get full text

Is elective neck dissection necessary for patients with cT3-4N0 parotid gland cancer? by Adachi, Masahiro, Tomioka, Toshifumi, Fujii, Satoshi, Morishita, Yohei, Okano, Wataru, Shinozaki, Takeshi, Matsuura, Kazuto, Hayashi, Ryuichi

“…Management of the cervical lymph nodes in patients with cT3-4N0 parotid gland cancer (PGC) has been controversial. This study investigated the need for…”
Get full text

Comparison between three age-stratified cohorts reveals poor prognosis of young patients with tongue carcinoma by Baba, Daisuke, Matsuura, Kazuto, Wakabayashi, Masashi, Morishita, Yohei, Nishiya, Yukio, Okano, Wataru, Tomioka, Toshifumi, Shinozaki, Takeshi, Hayashi, Ryuichi

“…Objectives Investigation of the prognosis of young patients with tongue carcinoma has been the focus of several recent studies aimed at improving future…”
Get full text

Atrophy of the ipsilateral mammillary body in unilateral hippocampal sclerosis shown by thin-slice-reconstructed volumetric analysis by Morishita, Yohei, Mugikura, Shunji, Mori, Naoko, Tamura, Hajime, Sato, Shiho, Akashi, Toshiaki, Jin, Kazutaka, Nakasato, Nobukazu, Takase, Kei

“…Purpose Conventional volumetric analysis could not detect ipsilateral atrophy of the mammillary body in patients with unilateral hippocampal sclerosis. By…”
Get full text

A case of Epstein–Barr virus-positive mucocutaneous ulcer of the hypopharynx: a mimicker of hypopharyngeal squamous cell carcinoma by Masuoka, Sota, Hiyama, Takashi, Kuno, Hirofumi, Morishita, Yohei, Sakashita, Shingo, Kobayashi, Tatsushi

“…Epstein–Barr virus-positive mucocutaneous ulcer (EBVMCU) is a new disease, described by the World Health Organization in 2017. It has been recognized as a…”
Get full text

Assessment and agreement of the CT appearance pattern and its severity grading of radiation-induced lung injury after stereotactic body radiotherapy for lung cancer by Yamamoto, Takaya, Kadoya, Noriyuki, Morishita, Yohei, Sato, Yoshinao, Matsushita, Haruo, Umezawa, Rei, Ishikawa, Yojiro, Takahashi, Noriyoshi, Katagiri, Yu, Takeda, Ken, Jingu, Keiichi

“…Radiographic severity of radiation-induced lung injury (RILI) has not been well-studied. The goal of this study was to assess the CT appearance pattern and…”
Get full text

A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution by Fuchs, Sebastian W., Lackner, Gerald, Morinaka, Brandon I., Morishita, Yohei, Asai, Teigo, Riniker, Sereina, Piel, Jörn

“…Ribosomally synthesized and posttranslationally modified peptide natural products (RiPPs) exhibit diverse structures and bioactivities and are classified into…”
Get full text

Semi-synthesis of a DNA-Tagged Polyketide–Peptide Hybrid Macrocycle Using a Biosynthetically Prepared Fungal Macrolide as a Synthetic Component by Koremura, Soya, Sugawara, Akihiro, Morishita, Yohei, Ozaki, Taro, Asai, Teigo

“…Presented herein is a synthetic biological method using genome mining and heterologous expression systems that provides access to natural products with…”
Get full text

Predicting isocitrate dehydrogenase status among adult patients with diffuse glioma using patient characteristics, radiomic features, and magnetic resonance imaging: Multi-modal analysis by variable vision transformer by Usuzaki, Takuma, Inamori, Ryusei, Shizukuishi, Takashi, Morishita, Yohei, Takagi, Hidenobu, Ishikuro, Mami, Obara, Taku, Takase, Kei

“…To evaluate the performance of the multimodal model, termed variable Vision Transformer (vViT), in the task of predicting isocitrate dehydrogenase (IDH) status…”
Get full text

Identifying key factors for predicting O6-Methylguanine-DNA methyltransferase status in adult patients with diffuse glioma: a multimodal analysis of demographics, radiomics, and MRI by variable Vision Transformer by Usuzaki, Takuma, Takahashi, Kengo, Inamori, Ryusei, Morishita, Yohei, Shizukuishi, Takashi, Takagi, Hidenobu, Ishikuro, Mami, Obara, Taku, Takase, Kei

“…Purpose This study aimed to perform multimodal analysis by vision transformer (vViT) in predicting O6-methylguanine-DNA methyl transferase (MGMT) promoter…”
Get full text