Search Results - "Morishita, Ken"

Development of Scaled-Up Synthetic Method for Retinoid X Receptor Agonist NEt-3IB Contributing to Sustainable Development Goals by Takamura, Yuta, Morishita, Ken-ichi, Kikuzawa, Shota, Watanabe, Masaki, Kakuta, Hiroki

“…Small-molecular drugs, which are generally inexpensive compared with biopharmaceuticals and can often be taken orally, may contribute to the Sustainable…”
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Retinoid X Receptor Ligands with Anti-Type 2 Diabetic Activity by Morishita, Ken-Ichi, Kakuta, Hiroki

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-dependent transcription factor that plays an important role in regulating glucose…”
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RXR Partial Agonist Produced by Side Chain Repositioning of Alkoxy RXR Full Agonist Retains Antitype 2 Diabetes Activity without the Adverse Effects by Kawata, Kohei, Morishita, Ken-ichi, Nakayama, Mariko, Yamada, Shoya, Kobayashi, Toshiki, Furusawa, Yuki, Arimoto-Kobayashi, Sakae, Oohashi, Toshitaka, Makishima, Makoto, Naitou, Hirotaka, Ishitsubo, Erika, Tokiwa, Hiroaki, Tai, Akihiro, Kakuta, Hiroki

“…We previously reported RXR partial agonist CBt-PMN (1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid: 5, EC50 = 143…”
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Modification at the Lipophilic Domain of RXR Agonists Differentially Influences Activation of RXR Heterodimers by Ohsawa, Fuminori, Morishita, Ken-ichi, Yamada, Shoya, Makishima, Makoto, Kakuta, Hiroki

“…RXR permissive heterodimers are reported to be activated differently depending upon the chemical structure of RXR agonists, but the relationship of agonist…”
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The First Potent Subtype-Selective Retinoid X Receptor (RXR) Agonist Possessing a 3-Isopropoxy-4-isopropylphenylamino Moiety, NEt-3IP (RXRα/β-dual agonist) by Takamatsu, Kayo, Takano, Atsushi, Yakushiji, Nobumasa, Morohashi, Kazunori, Morishita, Ken-ichi, Matsuura, Nobuyasu, Makishima, Makoto, Tai, Akihiro, Sasaki, Kenji, Kakuta, Hiroki

“…Retinoid X receptor (RXR) agonists (rexinoids) are attracting much attention for their use in treatment of cancers, including tamoxifen‐resistant breast cancer…”
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Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity by Morishita, Ken-ichi, Yakushiji, Nobumasa, Ohsawa, Fuminori, Takamatsu, Kayo, Matsuura, Nobuyasu, Makishima, Makoto, Kawahata, Masatoshi, Yamaguchi, Kentaro, Tai, Akihiro, Sasaki, Kenji, Kakuta, Hiroki

“…Retinoid X receptor (RXR) ligands are attractive candidates for clinical application because of their activity against tamoxifen-resistant breast cancer,…”
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Reduction of Lipophilicity at the Lipophilic Domain of RXR Agonists Enables Production of Subtype Preference: RXRα-Preferential Agonist Possessing a Sulfonamide Moiety by Takamatsu, Kayo, Takano, Atsushi, Yakushiji, Nobumasa, Morishita, Ken-ichi, Matsuura, Nobuyasu, Makishima, Makoto, Ali, Hamed Ismail, Akaho, Eiichi, Tai, Akihiro, Sasaki, Kenji, Kakuta, Hiroki

“…Retinoid X receptor agonists (RXR agonists, rexinoids) are interesting candidates for the treatment of cancers such as tamoxifen‐resistant breast cancer and…”
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Small slow-strain steps and their forerunners observed in gold mine in South Africa by Naoi, Makoto, Ogasawara, Hiroshi, Takeuchi, Junichi, Yamamoto, Akihito, Shimoda, Naoyuki, Morishita, Ken, Ishii, Hiroshi, Nakao, Shigeru, van Aswegen, Gerrie, Mendecki, Aleksander J., Lenegan, Patrick, Ebrahim-Trollope, Rookshana, Iio, Yoshihisa

“…The Research Group for Semi‐controlled Earthquake‐generation Experiments in South African deep gold mines (SeeSA) has continuously monitored strain changes…”
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Photo-reflection and laser-ablation properties of phthalocyanine/perylene derivative bilayer by Nagai, Keiji, Morishita, Ken-ichiro, Yoshida, Hidetsugu, Norimatsu, Takayoshi, Miyanaga, Noriaki, Izawa, Yasukazu, Yamanaka, Tatsuhiko

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1,1‘-Binaphthyl-2,2‘-diyl Phosphoroselenoyl Chloride as a Chiral Molecular Tool for the Preparation of Enantiomerically Pure Alcohols and Amines by Murai, Toshiaki, Matsuoka, Daichi, Morishita, Ken

“…Enantiomerically pure phosphoroselenoyl chloride bearing a binaphthyl group was synthesized. This phosphoroselenoyl chloride was used to discriminate and…”
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Synthesis of 1,1′-Binaphthyl-2,2′-diyl Phosphoroselenoic Amides and Their Conversion to Optically Pure Phosphoramidites by Murai, Toshiaki, Inaji, Shinsuke, Morishita, Ken, Shibahara, Fumitoshi, Tokunaga, Makoto, Obora, Yasushi, Tsuji, Yasushi

“…Optically pure phosphoroselenoyl chloride was reacted with racemic amines to give phosphoroselenoic amides as two diastereomeric mixtures in high yields. The…”
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Calculation of Optimal Ground Post Resistance for Reducing Emissions from Chassis-Mounted Printed Circuit Boards by Xinbo He, Hubing, T, Haixin Ke, Kobayashi, N, Morishita, K, Harada, T

“…When a printed circuit board (PCB) is mounted to a metal chassis, the cavity formed between the circuit board ground and the chassis can resonate at certain…”
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An investigation of the effect of grounding pads on power bus resonance characteristics by Morishita, K., Hubing, T., Xinbo He, Kobayashi, N., Harada, T.

“…This paper describes the effect of grounding pads on power bus resonance characteristics in multilayer printed circuit boards (PCBs). The resonance…”
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Coupling Analysis of PCB-Chassis Systems with Signal Lines and Via Structures using SPICE by Kobayashi, N., Morishita, K., Kusumoto, M., Harada, T., Hubing, T.

“…This paper describes the SPICE modeling of printed circuit boards (PCBs) with signal lines and via structures electrically connected to a metal chassis. First,…”
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Reduction of lipophilicity at the lipophilic domain of RXR agonists enables production of subtype preference: RXRalpha-preferential agonist possessing a sulfonamide moiety by Takamatsu, Kayo, Takano, Atsushi, Yakushiji, Nobumasa, Morishita, Ken-ichi, Matsuura, Nobuyasu, Makishima, Makoto, Ali, Hamed Ismail, Akaho, Eiichi, Tai, Akihiro, Sasaki, Kenji, Kakuta, Hiroki

“…Retinoid X receptor agonists (RXR agonists, rexinoids) are interesting candidates for the treatment of cancers such as tamoxifen-resistant breast cancer and…”
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Radionuclide Imaging for Assessment of Myocarditis and Postmyocarditic State in Infant and Children: Thallium-201 Myocardial Imaging and Technetium-99m-HSA Gated Equilibrium Ventriculography by SAJI, Tsutomu, MATSUO, Norio, HASHIGUCHI, Reiko, SATO, Keiko, UMEZAWA, Tetsuro, MORISHITA, Ken, YAMAZAKI, Junichi, KAWAMURA, Yasuaki, OKUZUMI, Kazuo, YABE, Yoshimasa

“…T1-201 myocardial imaging and Tc-99m-HSA gated equilibrium ventriculography were performed in 1 infant and 11 children between 2 months old and 12 years old…”
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Analysis of EBG structures using SPICE models of multiple planes by Kobayashi, N., Morishita, K., Harada, T.

“…Compared to measurements, SPICE models of multiple planes are demonstrated to be effective for analyzing electromagnetic band gap (EBG) structures where unit…”
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Digital tags: data with restricted accessibility for e-commerce applications by Kambayashi, Yahiko, Tarumi, Hiroyuki, Morishita, Ken

“…A digital tag is defined to be attached to objects and there are the following two kinds of major functions; (1) tags are only accessible through base objects…”
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Digital tags:data with restricted accessibility for e-commerce applications by Kambayashi, Yahiko, Tarumi, Hiroyuki, Morishita, Ken

“…A digital tag is defined to be attached to objects and there are the following two kinds of major functions; (1) tags are only accessible through base objects…”
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Syntheses of Nitrogen-containing Heterocyclic Compounds. XLI. Reaction of Diazaphenanthrenes and Their N-Oxides with Methylsulfinyl Carbanion by HAMADA, YOSHIKI, MORISHITA, KENICHI, OZAWA, ISAO, TAKEUCHI, ISAO, HIROTA, MINORU

“…The reactions of 4, 6-phenanthroline (I) and its N-oxides, 6-oxide (II) and 4, 6-dioxide (IV), with dimethyl sulfoxide were carried out in the presence of…”
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