Search Results - "Morin, Andrew"

Collaboration gets the most out of software by Morin, Andrew, Eisenbraun, Ben, Key, Jason, Sanschagrin, Paul C, Timony, Michael A, Ottaviano, Michelle, Sliz, Piotr

“…By centralizing many of the tasks associated with the upkeep of scientific software, SBGrid allows researchers to spend more of their time on research…”
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A quick guide to software licensing for the scientist-programmer by Morin, Andrew, Urban, Jennifer, Sliz, Piotr

“…[...]proprietary licenses are often very restrictive for end-users. [...]in our software-dependent information age, few laws are influencing our professional…”
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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors by Mulcahy Levy, Jean M, Zahedi, Shadi, Griesinger, Andrea M, Morin, Andrew, Davies, Kurtis D, Aisner, Dara L, Kleinschmidt-DeMasters, B K, Fitzwalter, Brent E, Goodall, Megan L, Thorburn, Jacqueline, Amani, Vladimir, Donson, Andrew M, Birks, Diane K, Mirsky, David M, Hankinson, Todd C, Handler, Michael H, Green, Adam L, Vibhakar, Rajeev, Foreman, Nicholas K, Thorburn, Andrew

“…Kinase inhibitors are effective cancer therapies, but tumors frequently develop resistance. Current strategies to circumvent resistance target the same or…”
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Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAFV600E-Mutant Human Glioma by Schreck, Karisa C., Morin, Andrew, Zhao, Guisheng, Allen, Amy N., Flannery, Patrick, Glantz, Michael, Green, Adam L., Jones, Chris, Jones, Kenneth L., Kilburn, Lindsay B., Nazemi, Kellie J., Samuel, David, Sanford, Bridget, Solomon, David A., Wang, Jiawan, Pratilas, Christine A., Nicolaides, Theodore, Mulcahy Levy, Jean M.

“…Abstract Purpose: Selective RAF-targeted therapy is effective in some patients with BRAFV600E-mutated glioma, though emergent and adaptive resistance occurs…”
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Evaluation of Computational Models for Electron Transpiration Cooling by Campbell, Nicholas S., Hanquist, Kyle, Morin, Andrew, Meyers, Jason, Boyd, Iain

“…Recent developments in the world of hypersonic flight have brought increased attention to the thermal response of materials exposed to high-enthalpy gases. One…”
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Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas by Grob, Sydney T, Nobre, Liana, Campbell, Kristen R, Davies, Kurtis D, Ryall, Scott, Aisner, Dara L, Hoffman, Lindsey, Zahedi, Shadi, Morin, Andrew, Crespo, Michele, Nellan, Anandani, Green, Adam L, Foreman, Nicholas, Vibhakar, Rajeev, Hankinson, Todd C, Handler, Michael H, Hawkins, Cynthia, Tabori, Uri, Kleinschmidt-DeMasters, B K, Mulcahy Levy, Jean M

“…Abstract Background The mitogen-activated protein kinases/extracelluar signal-regulated kinases pathway is involved in cell growth and proliferation, and…”
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Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs by Bepler, Tristan, Morin, Andrew, Rapp, Micah, Brasch, Julia, Shapiro, Lawrence, Noble, Alex J., Berger, Bonnie

“…Cryo-electron microscopy is a popular method for the determination of protein structures; however, identifying a sufficient number of particles for analysis…”
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Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats by Koehnle, Thomas J, Russell, Matthew C, Morin, Andrew S, Erecius, Lesa F, Gietzen, Dorothy W

“…Diets deficient in an indispensable amino acid have long been known to suppress food intake in rats. Detection of dietary deficiency takes place in the…”
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Security Shocks and Cryptocurrency Market Manipulations by Morin, Andrew

“…As the cryptocurrency market has expanded, it has adopted a number of traditional financial market instruments. While supporters often cite the abolition of…”
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LGG-55. Autophagy sensitizes CNS tumors to targeted therapy by lowering their apoptotic threshold by Crespo, Michele, Zahedi, Shadi, Morin, Andrew, Wodetzki, Darya, Caino, Cecilia, Levy, Jean Mulcahy

“…Abstract Autophagy inhibition improves the effectiveness and overcomes RAF pathway inhibition (RAFi) resistance across multiple CNS tumors and molecularly…”
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MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation by Ying, Wei, Tseng, Alexander, Chang, Richard Cheng-An, Morin, Andrew, Brehm, Tyler, Triff, Karen, Nair, Vijayalekshmi, Zhuang, Guoqing, Song, Hui, Kanameni, Srikanth, Wang, Haiqing, Golding, Michael C, Bazer, Fuller W, Chapkin, Robert S, Safe, Stephen, Zhou, Beiyan

“…Polarized activation of adipose tissue macrophages (ATMs) is crucial for maintaining adipose tissue function and mediating obesity-associated cardiovascular…”
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LGG-57. BH3 MIMETICS IMPROVE RESPONSE TO AUTOPHAGY INHIBITION IN BRAFV600E GLIOMAS by Crespo, Michele, Zahedi, Shadi, Morin, Andrew, Wodetzski, Darya, Groat, Madeline, Bratbak, Emil, Jones, Kendra, Griesinger, Andrea, Caino, Cecilia, Levy, Jean Mulcahy

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ATRT-24. CDK7 Inhibition in AT/RT by Morin, Andrew, Wodetzki, Darya, Veo, Bethany, Pierce, Angela, Zahedi, Shadi, Crespo, Michele, Venkataraman, Sujatha, Vibhakar, Rajeev, Mulcahy-Levy, Jean

“…Abstract Atypical teratoid/rhabdoid tumors (AT/RT) are CNS tumors with a 5-year survival of ~35%. AT/RT is characterized by loss-of-function mutations in the…”
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ATRT-20. CDK7 INHIBITION IN AT/RT by Morin, Andrew, Veo, Bethany, Fosmire, Susan, Crespo, Michele, Zahedi, Shadi, Vibhakar, Rajeev, Levy, Jean M Mulcahy

“…Abstract Atypical teratoid/rhabdoid tumors (AT/RT) are characterized by loss-of-function mutations in the SMARCB1 component (and less commonly SMARCA4) of the…”
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IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages by Li, Chuan, Ying, Wei, Huang, Zheping, Brehm, Tyler, Morin, Andrew, Vella, Anthony T, Zhou, Beiyan

“…Aberrant proinflammatory and suppressed anti-inflammatory (alternative; M2) macrophage activation underlies the chronic inflammation associated with obesity…”
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Occupational Rehabilitation Following Open Mesh Surgical Repair of an Inguinal Hernia by Pesanelli, Kelly E, Cigna, Joseph A, Basu, Shantanu G, Morin, Andrew R

“…The purpose of this case report is to describe an occupational rehabilitation program for a person whose work-related inguinal hernia was surgically repaired…”
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RARE-18. NF1-MUTATED TUMORS EXHIBIT INCREASED SENSITIVITY TO AUTOPHAGY INHIBITION ALONE AND IN COMBINATION WITH MEK INHIBITION by Baird-Daniel, Eliza, Zahedi, Shadi, Morin, Andrew, Desmarais, Michelle, Williams, Kyle, Williams, Rory, Vibhakar, Rajeev, Foreman, Nicholas, Mulcahy-Levy, Jean

“…Abstract Background Autophagy inhibition is a potential treatment for central nervous system (CNS) tumors. Autophagy, a heavily regulated process by which…”
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Structural biology computing: Lessons for the biomedical research sciences by Morin, Andrew, Sliz, Piotr

“…ABSTRACT The field of structural biology, whose aim is to elucidate the molecular and atomic structures of biological macromolecules, has long been at the…”
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IRF6 Regulates Alternative Activation by Suppressing PPAR[gamma] in Male Murine Macrophages by Li, Chuan, Wei, Ying, Huang, Zheping, Brehm, Tyler, Morin, Andrew, Vella, Anthony T, Zhou, Beiyan

“…Abstract Aberrant proinflammatory and suppressed anti-inflammatory (alternative; M2) macrophage activation underlies the chronic inflammation associated with…”
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miR-150 regulates obesity-associated insulin resistance by controlling B cell functions by Ying, Wei, Tseng, Alexander, Chang, Richard Cheng-An, Wang, Haiqing, Lin, Yu-lieh, Kanameni, Srikanth, Brehm, Tyler, Morin, Andrew, Jones, Benjamin, Splawn, Taylor, Criscitiello, Michael, Golding, Michael C., Bazer, Fuller W., Safe, Stephen, Zhou, Beiyan

“…Adipose tissue resident B cells account for more than 20% of stromal cells within visceral adipose tissues; however, their functions in the adipose tissue…”
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