Search Results - "Morimura, Rii"
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Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish
Published in Developmental biology (15-10-2012)“…Dpysl2 (CRMP2) and Dpysl3 (CRMP4) are involved in neuronal polarity and axon elongation in cultured neurons. These proteins are expressed in various regions of…”
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Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord
Published in Developmental neurobiology (Hoboken, N.J.) (01-12-2013)“…ABSTRACT Dpysls (CRMPs) that were initially identified as mediator proteins of Semaphorin3a (Sema3a) signaling are involved in neuronal polarity and axon…”
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Abstract 3877: A unique layered 3D stromal tissue model for in vitro evaluation of immunologic agents and immune cell infiltration into microenviroment
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background The modulation of the immune system is a proven key target for cancer therapy, however, the complex interplay between immune cells and…”
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Abstract 1151: A unique layered 3D stromal tissue model for in vitro evaluation of immunologic agents and immune cell infiltration into cancer microenvironment
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Background; The modulation of the immune system is a proven key target for cancer therapy, however, the complex interplay between immune cells and…”
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In vitro throughput screening of anticancer drugs using patient-derived cell lines cultured on vascularized three-dimensional stromal tissues
Published in Acta biomaterialia (15-07-2024)“…The development of high-throughput anticancer drug screening methods using patient-derived cancer cell (PDC) lines that maintain their original characteristics…”
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Abstract 4580: Changes in the efficacy of anti-EGFR antibody drugs by exosomes derived from colorectal cancer patients
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Background: One of the biggest hurdles in cancer treatment is drug resistance. Exosomes are small membrane vesicles of endocytic origin, which contain…”
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Abstract 5036: Visualization of cancer-derived exosome-mediated angiogenesis in a layered 3D stromal tissue model
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Background: Exosomes are small vesicles of sizes ranging from 30 to 150 nm that originate from the endosomal luminal membrane and are constantly…”
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A unique ex vivo tumor model: 3D cocultured system with cancer and stromal cells including blood microvessels
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 211 Background: Importance of interaction between cancer and stromal cells has been widely recognized in tumor progression and tolerance against…”
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