Search Results - "Morignat, Eric"

Prion-like acceleration of a synucleinopathy in a transgenic mouse model by Mougenot, Anne-Laure, Nicot, Simon, Bencsik, Anna, Morignat, Eric, Verchère, Jérémy, Lakhdar, Latefa, Legastelois, Stéphane, Baron, Thierry

“…Abstract Our aim in this study was to investigate experimentally the possible in vivo transmission of a synucleinopathy, using a transgenic mouse model (TgM83)…”
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Assessment of the impact of the 2003 and 2006 heat waves on cattle mortality in France by Morignat, Eric, Perrin, Jean-Baptiste, Gay, Emilie, Vinard, Jean-Luc, Calavas, Didier, Hénaux, Viviane

“…While several studies have highlighted and quantified human mortality during the major heat waves that struck Western Europe in 2003 and 2006, the impact on…”
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‘Prion‐like’ propagation of the synucleinopathy of M83 transgenic mice depends on the mouse genotype and type of inoculum by Sargent, Dorian, Verchère, Jérémy, Lazizzera, Corinne, Gaillard, Damien, Lakhdar, Latifa, Streichenberger, Nathalie, Morignat, Eric, Bétemps, Dominique, Baron, Thierry

“…The M83 transgenic mouse is a model of human synucleinopathies that develops severe motor impairment correlated with accumulation of the pathological…”
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Devising an indicator to detect mid-term abortions in dairy cattle: a first step towards syndromic surveillance of abortive diseases by Bronner, Anne, Morignat, Eric, Hénaux, Viviane, Madouasse, Aurélien, Gay, Emilie, Calavas, Didier

“…Bovine abortion surveillance is essential for human and animal health because it plays an important role in the early warning of several diseases. Due to the…”
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Distribution and antimicrobial resistance of clinical and subclinical mastitis pathogens in dairy cows in Rhône-Alpes, France by Botrel, Marie-Anne, Haenni, Marisa, Morignat, Eric, Sulpice, Philippe, Madec, Jean-Yves, Calavas, Didier

“…The goal of this study was to estimate the distribution of pathogens, as well as their antimicrobial resistance pattern, in cows affected by clinical or…”
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Assessing the mandatory bovine abortion notification system in France using unilist capture-recapture approach by Bronner, Anne, Hénaux, Viviane, Vergne, Timothée, Vinard, Jean-Luc, Morignat, Eric, Hendrikx, Pascal, Calavas, Didier, Gay, Emilie

“…The mandatory bovine abortion notification system in France aims to detect as soon as possible any resurgence of bovine brucellosis. However, under-reporting…”
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A case-control study on the origin of atypical scrapie in sheep, France by Fediaevsky, Alexandre, Morignat, Eric, Ducrot, Christian, Calavas, Didier

“…A matched case-control study (95 cases and 220 controls) was designed to study risk factors for atypical scrapie in sheep in France. We analyzed contacts with…”
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Temperature-mortality relationship in dairy cattle in France based on an iso-hygro-thermal partition of the territory by Morignat, Eric, Gay, Emilie, Vinard, Jean-Luc, Calavas, Didier, Hénaux, Viviane

“…The issue of global warming and more specifically its health impact on populations is increasingly concerning. The aim of our study was to evaluate the impact…”
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Protease-Sensitive and -Resistant Forms of Human and Murine Alpha-Synucleins in Distinct Brain Regions of Transgenic Mice (M83) Expressing the Human Mutated A53T Protein by Bétemps, Dominique, Arsac, Jean-Noël, Nicot, Simon, Canal, Dominique, Tlili, Habiba, Belondrade, Maxime, Morignat, Eric, Verchère, Jérémy, Gaillard, Damien, Bruyère-Ostells, Lilian, Mayran, Charly, Lakhdar, Latifa, Bougard, Daisy, Baron, Thierry

“…Human neurodegenerative diseases associated with the misfolding of the alpha-synuclein (aS) protein (synucleinopathies) are similar to prion diseases to the…”
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Atypical bovine spongiform encephalopathies, France, 2001-2007 by Biacabe, Anne-Gaëlle, Morignat, Eric, Vulin, Johann, Calavas, Didier, Baron, Thierry G M

“…In France, through exhaustive active surveillance, approximately 17.1 million adult cattle were tested for bovine spongiform encephalopathy from July 2001…”
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Prions of Ruminants Show Distinct Splenotropisms in an Ovine Transgenic Mouse Model by Baron, Thierry, Bencsik, Anna, Morignat, Eric

“…Background: Transmissible agents involved in prion diseases differ in their capacities to target different regions of the central nervous system and lymphoid…”
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Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model by Baron, Thierry, Bencsik, Anna, Biacabe, Anne-Gaëlle, Morignat, Eric, Bessen, Richard A.

“…Transmissible mink encepholapathy (TME) is a foodborne transmissible spongiform encephalopathy (TSE) of ranch-raised mink; infection with a ruminant TSE has…”
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A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-Type BSE in ovine transgenic mice by Baron, Thierry, Bencsik, Anna, Vulin, Johann, Biacabe, Anne-Gaëlle, Morignat, Eric, Verchere, Jérémy, Betemps, Dominique

“…The protease-resistant prion protein (PrP(res)) of a few natural scrapie isolates identified in sheep, reminiscent of the experimental isolate CH1641 derived…”
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Differentiation of prions from L-type BSE versus sporadic Creutzfeldt-Jakob disease by Nicot, Simon, Bencsik, Anna, Morignat, Eric, Mestre-Francés, Nadine, Perret-Liaudet, Armand, Baron, Thierry

“…We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the…”
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Transmissibility of Atypical Scrapie in Ovine Transgenic Mice: Major Effects of Host Prion Protein Expression and Donor Prion Genotype by Arsac, Jean-Noël, Bétemps, Dominique, Morignat, Eric, Féraudet, Cécile, Bencsik, Anna, Aubert, Denise, Grassi, Jacques, Baron, Thierry

“…Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and…”
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Unsupervised clustering of wildlife necropsy data for syndromic surveillance by Warns-Petit, Eva, Morignat, Eric, Artois, Marc, Calavas, Didier

“…The importance of wildlife disease surveillance is increasing, because wild animals are playing a growing role as sources of emerging infectious disease events…”
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Individual factors associated with L- and H-type Bovine Spongiform encephalopathy in France by Sala, Carole, Morignat, Eric, Oussaïd, Nadia, Gay, Emilie, Abrial, David, Ducrot, Christian, Calavas, Didier

“…Cattle with L-type (L-BSE) and H-type (H-BSE) atypical Bovine Spongiform encephalopathy (BSE) were identified in 2003 in Italy and France respectively before…”
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Oral Exposure to Paraquat Triggers Earlier Expression of Phosphorylated α-Synuclein in the Enteric Nervous System of A53T Mutant Human α-Synuclein Transgenic Mice by Naudet, Nicolas, Antier, Emilie, Gaillard, Damien, Morignat, Eric, Lakhdar, Latifa, Baron, Thierry, Bencsik, Anna

“…Abstract The misfolded α-synuclein protein, phosphorylated at serine 129 (pSer129 α-syn), is the hallmark of Parkinson disease (PD). Detected also in the…”
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Descriptive spatial analysis of BSE in western France by Abrial, David, Calavas, Didier, Lauvergne, Nathalie, Morignat, Eric, Ducrot, Christian

“…The spatial heterogeneity of Bovine Spongiform Encephalopathy (BSE) was analysed on the 84 cases confirmed in western France (WF) between August and December…”
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Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines by Chorfa, Areski, Bétemps, Dominique, Morignat, Eric, Lazizzera, Corinne, Hogeveen, Kevin, Andrieu, Thibault, Baron, Thierry

“…Epidemiological studies indicate a role of genetic and environmental factors in Parkinson's disease involving alterations of the neuronal α-synuclein (α-syn)…”
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