Search Results - "Morice, Sarah"

New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies? by Danieau, Geoffroy, Morice, Sarah, Rédini, Françoise, Verrecchia, Franck, Royer, Bénédicte Brounais-Le

“…Osteosarcoma and Ewing sarcoma are the most common malignant primary bone tumors mainly occurring in children, adolescents and young adults. Current standard…”
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PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution by Asante, Yaw, Benischke, Katharina, Osman, Issra, Ngo, Quy A., Wurth, Jakob, Laubscher, Dominik, Kim, Hyunmin, Udhayakumar, Bhavatharini, Khan, Md Imdadul H., Chin, Diana H., Porch, Jadon, Chakraborty, Maharshi, Sallari, Richard, Delattre, Olivier, Zaidi, Sakina, Morice, Sarah, Surdez, Didier, Danielli, Sara G., Schäfer, Beat W., Gryder, Berkley E., Wachtel, Marco

“…Activation of oncogenic gene expression from long-range enhancers is initiated by the assembly of DNA-binding transcription factors (TF), leading to…”
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Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis by Morice, Sarah, Danieau, Geoffroy, Tesfaye, Robel, Mullard, Mathilde, Brion, Régis, Dupuy, Maryne, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Redini, Françoise, Verrecchia, Franck

“…The poor survival rate of patients with osteosarcoma (OS), specifically with metastases at diagnosis, undergoes the urgency to develop new therapeutic…”
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SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression by Lézot, Frédéric, Corre, Isabelle, Morice, Sarah, Rédini, Françoise, Verrecchia, Franck

“…Primary bone tumors can be divided into two classes, benign and malignant. Among the latter group, osteosarcoma and Ewing sarcoma are the most prevalent…”
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Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors by Talbot, Julie, Dupuy, Maryne, Morice, Sarah, Rédini, Françoise, Verrecchia, Franck

“…Despite research and clinical advances during recent decades, bone cancers remain a leading cause of death worldwide. There is a low survival rate for patients…”
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ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells by Danieau, Geoffroy, Morice, Sarah, Renault, Sarah, Brion, Régis, Biteau, Kevin, Amiaud, Jérôme, Cadé, Marie, Heymann, Dominique, Lézot, Frédéric, Verrecchia, Franck, Rédini, Françoise, Brounais-Le Royer, Bénédicte

“…High-grade osteosarcomas are the most frequent malignant bone tumors in the pediatric population, with 150 patients diagnosed every year in France…”
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Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619 by Lavaud, Mélanie, Mullard, Mathilde, Tesfaye, Robel, Amiaud, Jérôme, Legrand, Mélanie, Danieau, Geoffroy, Brion, Régis, Morice, Sarah, Regnier, Laura, Dupuy, Maryne, Brounais-Le Royer, Bénédicte, Lamoureux, François, Ory, Benjamin, Rédini, Françoise, Verrecchia, Franck

“…Osteosarcoma (OS) is the most common malignant bone tumor in children and teenagers. In many cases, such as poor response to treatment or the presence of…”
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Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts by Talbot, Julie, Brion, Régis, Lamora, Audrey, Mullard, Mathilde, Morice, Sarah, Heymann, Dominique, Verrecchia, Franck

“…Although it has been demonstrated that human bone marrow stromal cells (hBMSCs) express the ubiquitous connexin43 (Cx43) and form functional gap junctions,…”
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EP200 Impact of local anesthetics on bone sarcoma: an in vitro study by Prosenz, Konstantin, Morice, Sarah, Aguirre, José, Surdez, Didier, Votta-Velis, Gina, Borgeat, Alain

“…Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)Retrospective and clinical studies on patient undergoing cancer…”
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Evaluation of the Role of AXL in Fusion-positive Pediatric Rhabdomyosarcoma Identifies the Small-molecule Inhibitor Bemcentinib (BGB324) as Potent Chemosensitizer by Danielli, Sara G, Wurth, Jakob, Morice, Sarah, Kisele, Samanta, Surdez, Didier, Delattre, Olivier, Bode, Peter K, Wachtel, Marco, Schäfer, Beat W

“…Rhabdomyosarcoma (RMS) is a highly aggressive pediatric cancer with features of skeletal muscle differentiation. More than 80% of the high-risk patients…”
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Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers? by Morice, Sarah, Danieau, Geoffroy, Rédini, Françoise, Brounais-Le-Royer, Bénédicte, Verrecchia, Franck

“…Osteosarcoma and Ewing sarcoma are the most prevalent bone pediatric tumors. Despite intensive basic and medical research studies to discover new therapeutics…”
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Abstract A07: Role of YAP/TEAD and YAP/Smad signaling pathways in osteosarcoma tumor growth and lung metastasis dissemination by Morice, Sarah, Mullard, Mathilde, Renault, Sarah, Amiaud, Jérôme, Brion, Régis, Corre, Isabelle, Gomez-Brouchet, Anne, Redini, Françoise, Verrecchia, Franck

“…Abstract Osteosarcoma (OS) is the main malignant primary bone tumor in children and adolescents for whom the prognosis remains poor, especially when metastases…”
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Abstract B26: Prometastatic effect of ICG-001, a β-catenin/CBP dependent transcription inhibitor, in osteosarcoma by Danieau, Geoffroy, Morice, Sarah, Renault, Sarah, Biteau, Kevin, Brion, Régis, Amiaud, Jérôme, Lezot, Frédéric, Verrecchia, Franck, Rédini, Françoise, Royer, Bénédicte Brounais-Le

“…Abstract Osteosarcoma is the most common malignant bone tumor in the pediatric population, representing around 4 cases per million people per year in the…”
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The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth by Morice, Sarah, Mullard, Mathilde, Brion, Regis, Dupuy, Maryne, Renault, Sarah, Tesfaye, Robel, Brounais-Le Royer, Bénédicte, Ory, Benjamin, Redini, Françoise, Verrecchia, Franck

“…Although some studies suggested that disruption of the Hippo signaling pathway is associated with osteosarcoma progression, the molecular mechanisms by which…”
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Abstract A29: Respective role of TEAD and Smad signaling in YAP-mediated osteosarcoma tumor growth and lung metastatic development by Morice, Sarah, Danieau, Geoffroy, Mullard, Mathilde, Amiaud, Jérôme, Brion, Régis, Renault, Sarah, Tesfaye, Robel, Dupuy, Maryne, Talbot, Julie, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Brouchet-Gomez, Anne, Rédini, Françoise, Verrecchia, Franck

“…Abstract Osteosarcoma (OS) is the main malignant primary bone tumor in children and adolescents for whom the prognosis remains poor, especially when metastases…”
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Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis by Morice, Sarah, Danieau, Geoffroy, Tesfaye, Robel, Mullard, Mathilde, Brion, Régis, Dupuy, Maryne, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Redini, Françoise, Verrecchia, Franck

“…Background The poor survival rate of patients with osteosarcoma (OS), specifically with metastases at diagnosis, undergoes the urgency to develop new…”
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Abstract 6267: The potassium channel SK1, a new target of EWS-FLI1, drives Ewing sarcoma cell proliferation by Dupuy, Maryne, Gueguinou, Maxime, Mullard, Mathilde, Tesfaye, Robel, Amiaud, Jerome, Morice, Sarah, Ory, Benjamin, Redini, Francoise, Vandier, Christophe, Verrecchia, Franck

“…Abstract Ewing sarcoma (ES) is the second most common primary bone tumor among children and teenagers. The survival rate for patients is about 70%, but drops…”
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Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth by Mullard, Mathilde, Cadé, Marie, Morice, Sarah, Dupuy, Maryne, Danieau, Geoffroy, Amiaud, Jérome, Renault, Sarah, Lézot, Frédéric, Brion, Régis, Thepault, Rose Anne, Ory, Benjamin, Lamoureux, François, Corre, Isabelle, Brounais-LeRoyer, Bénédicte, Rédini, Françoise, Verrecchia, Franck

“…Osteosarcoma (OS) and Ewing’s sarcoma (ES) are the most common malignant bone tumors in children and adolescents. In many cases, the prognosis remains very…”
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Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth by Mullard, Mathilde, Cadé, Marie, Morice, Sarah, Dupuy, Maryne, Danieau, Geoffroy, Amiaud, Jérome, Renault, Sarah, Lézot, Frédéric, Brion, Régis, Thepault, Rose Anne, Ory, Benjamin, Lamoureux, François, Corre, Isabelle, Brounais-Leroyer, Bénédicte, Rédini, Françoise, Verrecchia, Franck

“…Osteosarcoma (OS) and Ewing’s sarcoma (ES) are the most common malignant bone tumors in children and adolescents. In many cases, the prognosis remains very…”
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The place of the spirit: Toward a Trinitarian theology of location by Brubaker, Sarah Morice

“…Place and space has become a topic of theological currency in the late 20th and early 21st century, but its trinitarian implications merit further exploration…”
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