Search Results - "Moriarty, Thomas F."

Poly(Aspartic Acid) Functionalized Poly(ϵ-Caprolactone) Microspheres with Enhanced Hydroxyapatite Affinity as Bone Targeting Antibiotic Carriers by Rotman, Stijn G., Moriarty, Thomas F., Nottelet, Benjamin, Grijpma, Dirk W., Eglin, David, Guillaume, Olivier

“…Bone infection is a feared complication for patients with surgically fixed bone fractures and local antibiotic delivery is important in prophylaxis and…”
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Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections by Rotman, Stijn G., Thompson, Keith, Grijpma, Dirk W., Richards, Robert G., Moriarty, Thomas F., Eglin, David, Guillaume, Olivier

“…Bone infections are challenging to treat because of limited capability of systemic antibiotics to accumulate at the bone site. To enhance therapeutic action,…”
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Rapid Colorimetric Assay for Antimicrobial Susceptibility Testing of Pseudomonas aeruginosa by TUNNEY, Michael M, RAMAGE, Gordon, FIELD, Tyler R, MORIARTY, Thomas F, STOREY, Douglas G

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antimicrobial delivery systems for local infection prophylaxis in orthopedic- and trauma surgery by ter Boo, Gert-Jan A, Grijpma, Dirk W, Moriarty, Thomas F, Richards, Robert G, Eglin, David

“…Abstract Infectious complications occur in a minor but significant portion of the patients undergoing joint replacement surgery or fracture fixation,…”
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Peri‐anesthetic hypothermia in rodents: A factor to consider for accurate and reproducible outcomes in orthopedic device‐related infection studies by Constant, Caroline, Moriarty, Thomas F., Arens, Daniel, Pugliese, Brenna, Zeiter, Stephan

“…Orthopedic device‐related infection (ODRI) preclinical models are widely used in translational research. Most ODRI models require induction of general…”
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Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods by Hofstee, Marloes I, Muthukrishnan, Gowrishankar, Atkins, Gerald J, Riool, Martijn, Thompson, Keith, Morgenstern, Mario, Stoddart, Martin J, Richards, Robert G, Zaat, Sebastian A J, Moriarty, Thomas F

“…Osteomyelitis is an inflammation of the bone and bone marrow that is most commonly caused by a Staphylococcus aureus infection. Much of our understanding of…”
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A Hyaluronic Acid Hydrogel Loaded with Gentamicin and Vancomycin Successfully Eradicates Chronic Methicillin-Resistant Staphylococcus aureus Orthopedic Infection in a Sheep Model by Boot, Willemijn, Schmid, Tanja, D'Este, Matteo, Guillaume, Olivier, Foster, Andrew, Decosterd, Laurent, Richards, Robert G, Eglin, David, Zeiter, Stephan, Moriarty, Thomas F

“…Implantable orthopedic devices have had an enormously positive impact on human health; however, despite best practice, patients are prone to developing…”
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The 2023 Orthopaedic Research Society International Consensus Meeting on musculoskeletal infection by Moriarty, Thomas F., Hickok, Noreen J., Saeed, Kordo, Schaer, Thomas P., Chen, Antonia F., Schwarz, Edward M.

“…The Orthopaedic Research Society's Research Interest Group completed its international consensus meeting (ICM) on musculoskeletal infections (MSKI) following…”
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Development of an ex vivo model to study Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network by Vanvelk, Niels, de Mesy Bentley, Karen L, Verhofstad, Michael H J, Metsemakers, Willem-Jan, Moriarty, Thomas F, Siverino, Claudia

“…Staphylococcus aureus has multiple mechanisms to evade the host's immune system and antibiotic treatment. One such mechanism is the invasion of the osteocyte…”
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Single‐stage revision of MRSA orthopedic device‐related infection in sheep with an antibiotic‐loaded hydrogel by Foster, Andrew L., Boot, Willemijn, Stenger, Valentina, D'Este, Matteo, Jaiprakash, Anjali, Eglin, David, Zeiter, Stephan, Richards, Robert G., Moriarty, Thomas F.

“…Local antimicrobial therapy is an integral aspect of treating orthopedic device‐related infection (ODRI), which is conventionally administered via…”
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Impact of low bone mass and antiresorptive therapy on antibiotic efficacy in a rat model of orthopedic device‐related infection by Thompson, Keith, Freitag, Linda, Styger, Ursula, Camenisch, Karin, Zeiter, Stephan, Arens, Daniel, Richards, R. Geoff, Moriarty, Thomas F., Stadelmann, Vincent A.

“…A significant proportion of orthopedic devices are implanted in osteoporotic patients, but it is currently unclear how estrogen deficiency and/or exposure to…”
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Clinical practice in prevention of fracture-related infection: An international survey among 1197 orthopaedic trauma surgeons by Puetzler, Jan, Zalavras, Charalampos, Moriarty, Thomas F., Verhofstad, Michael H.J., Kates, Stephen L., Raschke, Michael -J., Rosslenbroich, Steffen, Metsemakers, Willem-J.

“…•Worldwide heterogeneity exists among orthopaedic trauma surgeons with respect to the measures taken to prevent FRI.•There is a lack of consensus concerning…”
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Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis by Tunney, Michael M, Field, Tyler R, Moriarty, Thomas F, Patrick, Sheila, Doering, Gerd, Muhlebach, Marianne S, Wolfgang, Matthew C, Boucher, Richard, Gilpin, Deirdre F, McDowell, Andrew, Elborn, J. Stuart

“…Pulmonary infection in cystic fibrosis (CF) is polymicrobial and it is possible that anaerobic bacteria, not detected by routine aerobic culture methods,…”
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Ozonated saline shows activity against planktonic and biofilm growing Staphylococcus aureus in vitro: a potential irrigant for infected wounds by Al-Saadi, Hayder, Potapova, Inga, Rochford, Edward TJ, Moriarty, Thomas F, Messmer, Peter

“…Infections associated with deep wounds require extensive surgical and medical care. New adjunctive treatments are required to aid in the eradication of the…”
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Implant retention in a rabbit model of fracture-related infection: similar infection clearance but impaired bone healing in delayed compared to early infection by Puetzler, Jan, Vallejo Diaz, Alejandro, Gosheger, Georg, Schulze, Martin, Arens, Daniel, Zeiter, Stephan, Siverino, Claudia, Richards, Robert G., Moriarty, Thomas F.

“…Aims Fracture-related infection (FRI) is commonly classified based on the time of onset of symptoms. Early infections (< two weeks) are treated with…”
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Hyaluronic acid derivatives and its polyelectrolyte complexes with gentamicin as a delivery system for antibiotics by Boo, Gert‐Jan A., Richards, Robert G., Moriarty, Thomas F., Grijpma, Dirk W., Eglin, David

“…Repeated administration of gentamicin (Gen) is often necessary to have efficacious pharmacokinetics in both infection prophylaxis and treatment. In order to…”
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Influence of material and microtopography on the development of local infection in vivo: experimental investigation in rabbits by Moriarty, Thomas F, Debefve, Laurence, Boure, Ludovic, Campoccia, Davide, Schlegel, Urs, Richards, Robert G

“…Polishing the surface of internal fracture fixation (IFF) implant materials can ease implant removal and reduce irritation to gliding tissues by reducing soft…”
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In Vivo Evaluation of the Effect of Intramedullary Nail Microtopography on the Development of Local Infection in Rabbits by Moriarty, Thomas F., Campoccia, Davide, Nees, Stephanie K., Boure, Ludovic P., Richards, Robert G.

“…Background and Aim Fractures of the tibia and femoral diaphysis are commonly repaired by intramedullary (IM) nails, which are currently composed of either…”
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Current Concepts of Osteomyelitis by Hofstee, Marloes I., Muthukrishnan, Gowrishankar, Atkins, Gerald J., Riool, Martijn, Thompson, Keith, Morgenstern, Mario, Stoddart, Martin J., Richards, Robert G., Zaat, Sebastian A.J., Moriarty, Thomas F.

“…Osteomyelitis is an inflammation of the bone and bone marrow that is most commonly caused by a Staphylococcus aureus infection. Much of our understanding of…”
Get full text

Implant retention in a rabbit model of fracture-related infection by Puetzler, Jan, Vallejo Diaz, Alejandro, Gosheger, Georg, Schulze, Martin, Arens, Daniel, Zeiter, Stephan, Siverino, Claudia, Richards, Robert G, Moriarty, Thomas F

“…Fracture-related infection (FRI) is commonly classified based on the time of onset of symptoms. Early infections (< two weeks) are treated with debridement,…”
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