Search Results - "Moriarty, T"

Skeletal infections: microbial pathogenesis, immunity and clinical management by Masters, Elysia A., Ricciardi, Benjamin F., Bentley, Karen L. de Mesy, Moriarty, T. Fintan, Schwarz, Edward M., Muthukrishnan, Gowrishankar

“…Osteomyelitis remains one of the greatest risks in orthopaedic surgery. Although many organisms are linked to skeletal infections, Staphylococcus aureus…”
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Cascade‐Targeting Poly(amino acid) Nanoparticles Eliminate Intracellular Bacteria via On‐Site Antibiotic Delivery by Feng, Wenli, Li, Guofeng, Kang, Xiaoxu, Wang, Ruibai, Liu, Fang, Zhao, Dongdong, Li, Haofei, Bu, Fanqiang, Yu, Yingjie, Moriarty, T. Fintan, Ren, Qun, Wang, Xing

“…Intracellular bacteria in latent or dormant states tolerate high‐dose antibiotics. Fighting against these opportunistic bacteria has been a long‐standing…”
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Intraoperative loading of calcium phosphate-coated implants with gentamicin prevents experimental Staphylococcus aureus infection in vivo by Thompson, Keith, Petkov, Stoyan, Zeiter, Stephan, Sprecher, Christoph M, Richards, R Geoff, Moriarty, T Fintan, Eijer, Henk

“…Orthopedic device-related infection (ODRI) is a potentially devastating complication arising from the colonization of the device with bacteria, such as…”
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Evidence-Based Recommendations for Local Antimicrobial Strategies and Dead Space Management in Fracture-Related Infection by Metsemakers, Willem-Jan, Fragomen, Austin T., Moriarty, T. Fintan, Morgenstern, Mario, Egol, Kenneth A., Zalavras, Charalampos, Obremskey, William T., Raschke, Michael, McNally, Martin A.

“…Fracture-related infection (FRI) remains a challenging complication that imposes a heavy burden on orthopaedic trauma patients. The surgical management…”
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The production and application of bacterial exopolysaccharides as biomaterials for bone regeneration by Bagnol, R., Grijpma, D., Eglin, D., Moriarty, T.F.

“…Bacterial exopolysaccharides (EPS) are water-soluble polymers consisting of repeating sugar moieties that serve a wide range of functions for the bacterial…”
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Pathogenesis and management of fracture-related infection by Depypere, M., Morgenstern, M., Kuehl, R., Senneville, E., Moriarty, T.F., Obremskey, W.T., Zimmerli, W., Trampuz, A., Lagrou, K., Metsemakers, W-J.

“…Both fracture-related infections (FRIs) and periprosthetic joint infections (PJIs) include orthopaedic implant-associated infections. However, key aspects of…”
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Infection after fracture fixation: Current surgical and microbiological concepts by Metsemakers, W.J, Kuehl, R, Moriarty, T.F, Richards, R.G, Verhofstad, M.H.J, Borens, O, Kates, S, Morgenstern, M

“…Abstract One of the most challenging complications in trauma surgery is infection after fracture fixation (IAFF). IAFF may result in permanent functional loss…”
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Vancomycin displays time-dependent eradication of mature Staphylococcus aureus biofilms by Post, Virginia, Wahl, Peter, Richards, R Geoff, Moriarty, T Fintan

“…This study was carried out to determine the time and concentration profile required to achieve vancomycin-mediated eradication of Staphylococcus aureus…”
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Pathogenic Mechanisms and Host Interactions in Staphylococcus epidermidis Device-Related Infection by Sabaté Brescó, Marina, Harris, Llinos G, Thompson, Keith, Stanic, Barbara, Morgenstern, Mario, O'Mahony, Liam, Richards, R Geoff, Moriarty, T Fintan

“…is a permanent member of the normal human microbiota, commonly found on skin and mucous membranes. By adhering to tissue surface moieties of the host via…”
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Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing by Wallimann, A, Magrath, W, Thompson, K, Moriarty, T, Richards, R G, Akdis, C A, O'Mahony, L, Hernandez, C J

“…Bone healing complications such as delayed healing or non-union affect 5-10 % of patients with a long-bone fracture and lead to reduced quality of life and…”
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Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis by Méric, Guillaume, Mageiros, Leonardos, Pensar, Johan, Laabei, Maisem, Yahara, Koji, Pascoe, Ben, Kittiwan, Nattinee, Tadee, Phacharaporn, Post, Virginia, Lamble, Sarah, Bowden, Rory, Bray, James E., Morgenstern, Mario, Jolley, Keith A., Maiden, Martin C. J., Feil, Edward J., Didelot, Xavier, Miragaia, Maria, de Lencastre, Herminia, Moriarty, T. Fintan, Rohde, Holger, Massey, Ruth, Mack, Dietrich, Corander, Jukka, Sheppard, Samuel K.

“…Some of the most common infectious diseases are caused by bacteria that naturally colonise humans asymptomatically. Combating these opportunistic pathogens…”
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Fracture-related infection: A consensus on definition from an international expert group by Metsemakers, WJ, Morgenstern, M., McNally, M.A., Moriarty, T.F., McFadyen, I., Scarborough, M., Athanasou, N.A., Ochsner, P.E., Kuehl, R., Raschke, M., Borens, O., Xie, Z., Velkes, S., Hungerer, S., Kates, S.L., Zalavras, C., Giannoudis, P.V., Richards, R.G., Verhofstad, M.H.J.

“…Fracture-related infection (FRI) is a common and serious complication in trauma surgery. Accurately estimating the impact of this complication has been…”
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Phage therapy: A primer for orthopaedic trauma surgeons by Chen, Baixing, Moriarty, T.Fintan, Metsemakers, Willem-Jan, Chittò, Marco

“…Phage therapy (PT) continues to attract interest in the fight against fracture-related infection (FRI), particularly for recurring infections that have not…”
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Antibiotic Resistance of Commensal Staphylococcus aureus and Coagulase-Negative Staphylococci in an International Cohort of Surgeons: A Prospective Point-Prevalence Study by Morgenstern, Mario, Erichsen, Christoph, Hackl, Simon, Mily, Julia, Militz, Matthias, Friederichs, Jan, Hungerer, Sven, Bühren, Volker, Moriarty, T Fintan, Post, Virginia, Richards, R Geoff, Kates, Stephen L

“…Nasal colonization with antibiotic resistant bacteria represents both a risk factor for the colonized individual and their immediate contacts. Despite the fact…”
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Bacterial osteomyelitis in veterinary orthopaedics: Pathophysiology, clinical presentation and advances in treatment across multiple species by Gieling, Fabian, Peters, Sarah, Erichsen, Christoph, Richards, R. Geoff, Zeiter, Stephan, Moriarty, T. Fintan

“…•Review of the classification, clinical presentation, etiologic agents, and treatment of bacterial osteomyelitis in animals.•Provides additional…”
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Three-Dimensional In Vitro Staphylococcus aureus Abscess Communities Display Antibiotic Tolerance and Protection from Neutrophil Clearance by Hofstee, Marloes I, Riool, Martijn, Terjajevs, Igors, Thompson, Keith, Stoddart, Martin J, Richards, R Geoff, Zaat, Sebastian A J, Moriarty, T Fintan

“…is a prominent human pathogen in bone and soft-tissue infections. Pathophysiology involves abscess formation, which consists of central staphylococcal abscess…”
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Staphylococcus aureus From an Acute Fracture-related Infection Displays Important Bacteriological and Histopathologic Differences From a Chronic Equivalent in a Murine Bone Infection Model by Baertl, Susanne, Gens, Lena, Nehrbass, Dirk, Sumrall, Eric T., Zeiter, Stephan, Mannala, Gopala Krishna, Rupp, Markus, Walter, Nike, Richards, R. Geoff, Moriarty, T. Fintan, Alt, Volker

“…Staphylococcus aureus is the leading pathogen in fracture-related infection. Previous in vitro experiments, in vivo testing in wax moth larvae, and genomic…”
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The influence of biomechanical stability on bone healing and fracture-related infection: the legacy of Stephan Perren by Foster, Andrew L., Moriarty, T. Fintan, Zalavras, Charalampos, Morgenstern, Mario, Jaiprakash, Anjali, Crawford, Ross, Burch, Marc-Antoine, Boot, Willemijn, Tetsworth, Kevin, Miclau, Theodore, Ochsner, Peter, Schuetz, Michael A., Richards, R. Geoff, Metsemakers, Willem-Jan

“…•Biomechanical stability plays a critical role in fracture healing.•Although stability is often described to be essential for both prevention and treatment of…”
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American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer by Saslow, Debbie, Solomon, Diane, Lawson, Herschel W., Killackey, Maureen, Kulasingam, Shalini L., Cain, Joanna, Garcia, Francisco A. R., Moriarty, Ann T., Waxman, Alan G., Wilbur, David C., Wentzensen, Nicolas, Downs, Levi S., Spitzer, Mark, Moscicki, Anna‐Barbara, Franco, Eduardo L., Stoler, Mark H., Schiffman, Mark, Castle, Philip E., Myers, Evan R.

“…An update to the American Cancer Society (ACS) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented…”
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An Exopolysaccharide Produced by Bifidobacterium longum 35624® Inhibits Osteoclast Formation via a TLR2-Dependent Mechanism by Wallimann, Alexandra, Hildebrand, Maria, Groeger, David, Stanic, Barbara, Akdis, Cezmi A., Zeiter, Stephan, Richards, R. Geoff, Moriarty, T. Fintan, O’Mahony, Liam, Thompson, Keith

“…The probiotic Bifidobacterium longum subsp . longum 35624® ( B. longum 35624® ), with its surface exopolysaccharide (EPS624), has previously been demonstrated…”
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