Search Results - "Mori, Shiro"

Intranodal delivery of modified docetaxel: Innovative therapeutic method to inhibit tumor cell growth in lymph nodes by Sukhbaatar, Ariunbuyan, Mori, Shiro, Kodama, Tetsuya

“…Delivery of chemotherapeutic agents into metastatic lymph nodes (LNs) is challenging as they are unevenly distributed in the body. They are difficult to access…”
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Docetaxel administered through a novel lymphatic drug delivery system (LDDS) improved treatment outcomes for lymph node metastasis by Sukhbaatar, Ariunbuyan, Mori, Shiro, Sugiura, Tsuyoshi, Kodama, Tetsuya

“…Recently, sentinel lymph nodes (LNs) have been recognized as a starting point of hematogenous metastasis; thus, an increase in the control rate of LN…”
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Abstract 2005: Optimized range of osmotic pressure and viscosity for a lymphatic drug delivery system by Kodama, Tetsuya, Mori, Shiro

“…Abstract The lymphatic drug delivery system (LDDS) is a method that allows the injection of drugs into sentinel lymph nodes (SLNs) to facilitate their delivery…”
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Intralymphatic injection of chemotherapy drugs modulated with glucose improves their anticancer effect by Sukhbaatar, Ariunbuyan, Mori, Shiro, Shiga, Kiyoto, Kodama, Tetsuya

“…Lymph node metastasis (LNM) has a significant impact on cancer prognosis, emphasizing the need for effective treatment strategies. This study investigated the…”
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Study of the physicochemical properties of drugs suitable for administration using a lymphatic drug delivery system by Fukumura, Ryoichi, Sukhbaatar, Ariunbuyan, Mishra, Radhika, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya

“…Lymph node (LN) metastasis is thought to account for 20‐30% of deaths from head and neck cancer. The lymphatic drug delivery system (LDDS) is a new technology…”
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Drug formulation augments the therapeutic response of carboplatin administered through a lymphatic drug delivery system by Mishra, Radhika, Sukhbaatar, Ariunbuyan, Dorai, Arunkumar, Mori, Shiro, Shiga, Kiyoto, Kodama, Tetsuya

“…Treatment of metastatic lymph nodes (LNs) is challenging due to their unique architecture and biophysical traits. Systemic chemotherapy fails to impede tumor…”
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Combination therapy of lymphatic drug delivery and total body irradiation in a metastatic lymph node and lung mouse model by Sora, Shota, Sukhbaatar, Ariunbuyan, Fukushige, Shinichi, Mori, Shiro, Sakamoto, Maya, Kodama, Tetsuya

“…Chemotherapy using a lymphatic drug delivery system (LDDS) targeting lymph nodes (LNs) in the early stage of metastasis has a superior antitumor effect to…”
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Characterizing perfusion defects in metastatic lymph nodes at an early stage using high-frequency ultrasound and micro-CT imaging by Yamaki, Teppei, Sukhbaatar, Ariunbuyan, Mishra, Radhika, Kikuchi, Ryoichi, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya

“…A perfusion defect in a metastatic lymph node (LN) can be visualized as a localized area of low contrast on contrast-enhanced CT, MRI or ultrasound images…”
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Analysis of tumor vascularization in a mouse model of metastatic lung cancer by Sukhbaatar, Ariunbuyan, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya

“…Therapies targeting tumor vasculature would improve the treatment of lung metastasis, although the early changes in vascular structure are incompletely…”
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Metastatic lymph node targeted CTLA4 blockade: a potent intervention for local and distant metastases with minimal ICI-induced pneumonia by Mishra, Radhika, Sukhbaatar, Ariunbuyan, Mori, Shiro, Kodama, Tetsuya

“…Immune checkpoint blockade (ICB) elicits a strong and durable therapeutic response, but its application is limited by disparate responses and its associated…”
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Lymph node resection induces the activation of tumor cells in the lungs by Sukhbaatar, Ariunbuyan, Mori, Shiro, Saiki, Yuriko, Takahashi, Tetsu, Horii, Akira, Kodama, Tetsuya

“…Lymph node (LN) dissection is a crucial procedure for cancer staging, diagnosis and treatment, and for predicting patient survival. Activation of lung…”
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Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes by Zheng, Jinhua, Jia, Limin, Mori, Shiro, Kodama, Tetsuya

“…Surgical removal of primary tumors can promote the incidence of tumor metastasis. However, molecular mechanisms underlying this process remain unclear. We…”
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Evaluation of the enhanced permeability and retention effect in the early stages of lymph node metastasis by Mikada, Mamoru, Sukhbaatar, Ariunbuyan, Miura, Yoshinobu, Horie, Sachiko, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya

“…Most solid cancers spread to new sites via the lymphatics before hematogenous dissemination. However, only a small fraction of an intravenously administered…”
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Use of a Lymphatic Drug Delivery System and Sonoporation to Target Malignant Metastatic Breast Cancer Cells Proliferating in the Marginal Sinuses by Kato, Shigeki, Shirai, Yuko, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya

“…Lymph node (LN) metastasis through the lymphatic network is a major route for cancer dissemination. Tumor cells reach the marginal sinuses of LNs via afferent…”
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Developmental Changes in the Magnitude of Representational Momentum Among Nursery School Children: A Longitudinal Study by Mori, Shiro, Nakamoto, Hiroki, Shirai, Nobu, Imanaka, Kuniyasu

“…Representational momentum (RM) is a well-known phenomenon that occurs when a moving object vanishes suddenly and the memory of its final or vanishing position…”
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Experts in fast-ball sports reduce anticipation timing cost by developing inhibitory control by Nakamoto, Hiroki, Mori, Shiro

“…► Experts in fast ball sports adapt readily to changing environment. ► A better adaptation is due to efficient reprogramming of prepared motor output. ►…”
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Therapeutic effect of cisplatin given with a lymphatic drug delivery system on false‐negative metastatic lymph nodes by Tada, Asuka, Horie, Sachiko, Mori, Shiro, Kodama, Tetsuya

“…Systemic administration of drugs into the blood circulation is standard treatment for prevention of metastasis. However, systemic delivery cannot maintain…”
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Study of fluid dynamics reveals direct communications between lymphatic vessels and venous blood vessels at lymph nodes of mice by Takeda, Kazu, Mori, Shiro, Kodama, Tetsuya

“…Cancer cells metastasize to lymph nodes, with distant metastasis resulting in poor prognosis. The role of lymph node metastasis (LNM) in the spread of cancer…”
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New concept for the prevention and treatment of metastatic lymph nodes using chemotherapy administered via the lymphatic network by Kodama, Tetsuya, Matsuki, Daisuke, Tada, Asuka, Takeda, Kazu, Mori, Shiro

“…Intravenous chemotherapy has poor access to metastatic lymph nodes (LNs) and is limited by short-lived drug concentrations. Here, we describe the…”
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Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models by Kochi, Takashi, Imai, Yoshimichi, Takeda, Atsushi, Watanabe, Yukiko, Mori, Shiro, Tachi, Masahiro, Kodama, Tetsuya

“…Appropriate ischemia models are required for successful studies of therapeutic angiogenesis. While collateral routes are known to be present within the innate…”
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