Search Results - "Mori, Keiji"

C(sp3)–H Bond Functionalization Mediated by Hydride a Shift/Cyclization System by Mori, Keiji

“…An efficient catalytic internal redox reaction (hydride shift mediated C(sp3)–H bond functionalization) has been developed, which has the following salient…”
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Enantiodivergent Atroposelective Synthesis of Chiral Biaryls by Asymmetric Transfer Hydrogenation: Chiral Phosphoric Acid Catalyzed Dynamic Kinetic Resolution by Mori, Keiji, Itakura, Tsubasa, Akiyama, Takahiko

“…Reported herein is an enantiodivergent synthesis of chiral biaryls by a chiral phosphoric acid catalyzed asymmetric transfer hydrogenation reaction. Upon…”
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Chiral Magnesium Bisphosphate-Catalyzed Asymmetric Double C(sp3)–H Bond Functionalization Based on Sequential Hydride Shift/Cyclization Process by Mori, Keiji, Isogai, Ryo, Kamei, Yuto, Yamanaka, Masahiro, Akiyama, Takahiko

“…Described herein is a chiral magnesium bisphosphate-catalyzed asymmetric double C­(sp3)–H bond functionalization triggered by a sequential hydride…”
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Highly Diastereoselective Synthesis of Medium-Sized Carbocycle-Fused Piperidines via Sequential Hydride Shift Triggered Double C(sp3)–H Bond Functionalization by Kataoka, Miyabi, Otawa, Yuna, Ido, Natsuki, Mori, Keiji

“…Herein we report a diastereoselective synthesis of medium-sized carbocycle-fused piperidines via [1,n (n = 6, 7)]-[1,5]-sequential hydride shift triggered…”
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Selective Activation of Enantiotopic C(sp3)−Hydrogen by Means of Chiral Phosphoric Acid: Asymmetric Synthesis of Tetrahydroquinoline Derivatives by Mori, Keiji, Ehara, Kensuke, Kurihara, Kazuki, Akiyama, Takahiko

“…Chiral phosphoric acid-catalyzed asymmetric C−H functionalization has been achieved. In this process, enantiotopic C(sp3)−hydrogen is selectively activated by…”
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Highly Stereoselective Synthesis of Fused Tetrahydropyrans via Lewis-Acid-Promoted Double C(sp3)–H Bond Functionalization by Yokoo, Kazuma, Sakai, Dan, Mori, Keiji

“…We have achieved a sequential hydride-shift-triggered double C­(sp3)–H bond functionalization at a position adjacent to an oxygen atom and a benzylic/aliphatic…”
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Highly Diastereoselective Synthesis of Tetralin-fused Spirooxindoles via Lewis Acid-catalyzed C(sp3)–H Bond Functionalization by Machida, Mizuki, Mori, Keiji

“…A highly diastereoselective synthesis of tetralin-fused spirooxindole derivatives was described. Treatment of benzylidene oxindoles with a catalytic amount of…”
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Double C(sp3)–H Bond Functionalization Mediated by Sequential Hydride Shift/Cyclization Process: Diastereoselective Construction of Polyheterocycles by Mori, Keiji, Kurihara, Kazuki, Yabe, Shinnosuke, Yamanaka, Masahiro, Akiyama, Takahiko

“…Described herein are two novel types of double C(sp3)–H bond functionalizations triggered by a sequential hydride shift/cyclization process: (1) construction…”
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Enantioselective Synthesis of Multisubstituted Biaryl Skeleton by Chiral Phosphoric Acid Catalyzed Desymmetrization/Kinetic Resolution Sequence by Mori, Keiji, Ichikawa, Yuki, Kobayashi, Manato, Shibata, Yukihiro, Yamanaka, Masahiro, Akiyama, Takahiko

“…Described herein is the enantioselective synthesis of multisubstituted biaryl derivatives by chiral phosphoric acid catalyzed asymmetric bromination. Two…”
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Highly diastereoselective synthesis of tricyclic fused-pyrans by sequential hydride shift mediated double C(sp 3 )-H bond functionalization by Mori, Keiji, Umehara, Nobuaki, Akiyama, Takahiko

“…Described herein is the Brønsted acid-catalyzed double C(sp )-H bond functionalization of alkyl phenethyl ether derivatives. In this process, a…”
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Chiral Phosphoric Acid Catalyzed Transfer Hydrogenation: Facile Synthetic Access to Highly Optically Active Trifluoromethylated Amines by Henseler, Alexander, Kato, Masanori, Mori, Keiji, Akiyama, Takahiko

“…Amines to an end: Highly optically active α‐CF3‐functionalized amines can be obtained using metal‐free reaction conditions. The method involves the transfer…”
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The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi by Morishita, Yohei, Zhang, Huiping, Taniguchi, Tohru, Mori, Keiji, Asai, Teigo

“…Heterologous expression of a unique biosynthetic gene cluster (BGC) comprising a highly reducing polyketide synthase and stand-alone thioesterase genes in…”
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Direct Access to 9/6‐Fused Cycles via Sequential Hydride Shift Mediated Double C(sp3)−H Bond Functionalization by Nakamura, Issei, Anada, Masahiro, Sueki, Shunsuke, Makino, Kosho, Mori, Keiji

“…We have developed a sequential hydride shift process involving a [1,8]‐hydride shift. When cinnamylidene malonates having a biphenyl core were treated with 30…”
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Synthesis of C3-Symmetric Macrocyclic Triimines from Monomers Having Boc-protected Amine and Formyl Group by Moriya, Yu, Yamanaka, Masahiro, Mori, Keiji

“…A concise access to C3-symmetric macrocyclic triimines was developed. When biphenyls having a formyl group on one phenyl group and an NHBoc group on the other…”
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Diastereoselective Synthesis of CF3‑Substituted Spiroisochromans by [1,5]-Hydride Shift/Cyclization/Intramolecular Friedel–Crafts Reaction Sequence by Tamura, Risa, Kitamura, Eriko, Tsutsumi, Ryosuke, Yamanaka, Masahiro, Akiyama, Takahiko, Mori, Keiji

“…Developed herein is a diastereoselective synthesis of CF3-substituted spiroisochromans via C­(sp3)–H bond functionalization involving sequential…”
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Expeditious Synthesis of Benzopyrans via Lewis Acid-Catalyzed C−H Functionalization: Remarkable Enhancement of Reactivity by an Ortho Substituent by Mori, Keiji, Kawasaki, Taro, Sueoka, Shosaku, Akiyama, Takahiko

“…An expeditious construction of a benzopyran skeleton via Lewis acid-catalyzed C−H functionalization was achieved. In this process, a [1,5] hydride shift and…”
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Diastereoselective Synthesis of Multisubstituted Chroman Derivatives via Iminium Formation/Morita-Baylis-Hillman Reaction/Oxa-Michael Reaction Sequence by Ido, Natsuki, Mori, Keiji

“…A one-pot, highly diastereoselective synthesis of chroman derivatives with three contiguous stereogenic centers is described. In this reaction, three…”
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Synthesis of 3-Aryl-1-trifluoromethyltetrahydroisoquinolines by Brønsted Acid-Catalyzed C(sp3)H Bond Functionalization by Mori, Keiji, Umehara, Nobuaki, Akiyama, Takahiko

“…A concise route to 3‐aryl‐1‐trifluoromethyltetrahydroisoquinolines by a benzylic [1,5]‐hydride shift‐mediated CH bond functionalization was developed. The…”
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Catalytic Magnesium-Oppenauer Oxidation of Alcohols by Sasaki, Yuta, Yokoo, Kazuma, Mori, Keiji

“…A catalytic magnesium-Oppenauer oxidation reaction was developed. When a solution of alcohols in toluene was successively treated with 15–30 mol % of EtMgBr…”
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Concise Route to 3-Arylisoquinoline Skeleton by Lewis Acid Catalyzed C(sp3)–H Bond Functionalization and Its Application to Formal Synthesis of (±)-Tetrahydropalmatine by Mori, Keiji, Kawasaki, Taro, Akiyama, Takahiko

“…An expeditious route to furnish an isoquinoline skeleton via hydride shift mediated C–H bond functionalization was developed. In this process, an unusual…”
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