Search Results - "Morganti, Adele"

Bosentan for Treatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension by Jaïs, Xavier, MD, D'Armini, Andrea M., MD, Jansa, Pavel, MD, Torbicki, Adam, MD, Delcroix, Marion, MD, Ghofrani, Hossein A., MD, Hoeper, Marius M., MD, Lang, Irene M., MD, Mayer, Eckhard, MD, Pepke-Zaba, Joanna, MD, Perchenet, Loïc, PhD, Morganti, Adele, MSc, Simonneau, Gérald, MD, Rubin, Lewis J., MD

“…Objectives Our goal was to investigate the effect of treatment with the oral dual endothelin receptor antagonist bosentan on the hemodynamics and exercise…”
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BUILD-3: A Randomized, Controlled Trial of Bosentan in Idiopathic Pulmonary Fibrosis by KING, Talmadge E, BROWN, Kevin K, BEHR, Juergen, RAGHU, Ganesh, DU BOIS, Roland M, LYNCH, David A, MARTINEZ, Fernando, VALEYRE, Dominique, LECONTE, Isabelle, MORGANTI, Adele, ROUX, Sébastien

“…A previous trial of bosentan in idiopathic pulmonary fibrosis (IPF) showed a trend to delayed IPF worsening or death. Also, improvements in some measures of…”
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MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis by Bauer, Yasmina, White, Eric S, de Bernard, Simon, Cornelisse, Peter, Leconte, Isabelle, Morganti, Adele, Roux, Sebastien, Nayler, Oliver

“…Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis, which is characterised by destruction of normal lung…”
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Irinotecan Plus Gemcitabine Results in No Survival Advantage Compared With Gemcitabine Monotherapy in Patients With Locally Advanced or Metastatic Pancreatic Cancer Despite Increased Tumor Response Rate by ROCHA LIMA, Caio M, GREEN, Mark R, ROTCHE, Robert, MILLER, Wilson H, JEFFREY, G. Mark, CISAR, Laura A, MORGANTI, Adele, ORLANDO, Nicoletta, GRUIA, Gabriela, MILLER, Langdon L

“…This phase III, randomized, open-label, multicenter study compared the overall survival associated with irinotecan plus gemcitabine (IRINOGEM) versus…”
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A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy by Kefford, Richard F, Clingan, Philip R, Brady, Benjamin, Ballmer, Andrea, Morganti, Adele, Hersey, Peter

“…The endothelin system is implicated in the pathogenesis of melanoma. We evaluated the effects of bosentan - a dual endothelin receptor antagonist - in patients…”
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Randomized Trial of Macitentan/Tadalafil Single-Tablet Combination Therapy for Pulmonary Arterial Hypertension by Grünig, Ekkehard, Jansa, Pavel, Fan, Fenling, Hauser, Jakob A., Pannaux, Matthieu, Morganti, Adele, Rofael, Hany, Chin, Kelly M.

“…Endothelin receptor antagonist (ERA) and phosphodiesterase 5 inhibitor (PDE5i) combination therapy is recommended for low-/intermediate-risk pulmonary arterial…”
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Bosentan for Treatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension : BENEFiT (Bosentan Effects in iNopErable Forms of chronic Thromboembolic pulmonary hypertension), a Randomized, Placebo-Controlled Trial by JAÏS, Xavier, D'ARMINI, Andrea M, PERCHENET, Loïc, MORGANTI, Adele, SIMONNEAU, Gérald, RUBIN, Lewis J, JANSA, Pavel, TORBICKI, Adam, DELCROIX, Marion, GHOFRANI, Hossein A, HOEPER, Marius M, LANG, Irene M, MAYER, Eckhard, PEPKE-ZABA, Joanna

“…Our goal was to investigate the effect of treatment with the oral dual endothelin receptor antagonist bosentan on the hemodynamics and exercise capacity of…”
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Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial by RAGHU, Ganesh, MILLION-ROUSSEAU, Rachel, MORGANTI, Adele, PERCHENET, Loïc, BEHR, Juergen

“…Idiopathic pulmonary fibrosis is a progressive, fatal disease. This prospective, randomised, double-blind, multicentre, parallel-group, placebo-controlled…”
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MACITENTAN IN PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONNECTIVE TISSUE DISEASE: REAL-WORLD EVIDENCE FROM THE COMBINED OPUS/ORPHEUS DATA SETS by McLaughlin, Vallerie, Channick, Richard, Kim, Nick, Lammi, Matthew, Sulica, Roxana, Brand, Monika, Flynn, Megan, Leroy, Sandrine, Morganti, Adele, Chin, Kelly

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Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial by Matucci-Cerinic, Marco, Denton, Christopher P, Furst, Daniel E, Mayes, Maureen D, Hsu, Vivien M, Carpentier, Patrick, Wigley, Fredrick M, Black, Carol M, Fessler, Barri J, Merkel, Peter A, Pope, Janet E, Sweiss, Nadera J, Doyle, Mittie K, Hellmich, Bernhard, Medsger, Jr, Thomas A, Morganti, Adele, Kramer, Fabrice, Korn, Joseph H, Seibold, James R

“…Ischaemic digital ulcers (DUs) are common in patients with systemic sclerosis (SSc) and are a cause of disease-related morbidity. In an earlier trial,…”
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MACITENTAN IN THE ELDERLY POPULATION WITH PULMONARY ARTERIAL HYPERTENSION: REAL-WORLD EVIDENCE FROM THE COMBINED OPUS REGISTRY AND ORPHEUS COHORT by Chin, Kelly, Kim, Nick, McLaughlin, Vallerie, Frantz, Robert, Rodriguez-Lopez, Josanna, Brand, Monika, Flynn, Megan, Leroy, Sandrine, Morganti, Adele, Channick, Richard

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Effects of Long-Term Bosentan in Children With Pulmonary Arterial Hypertension by Rosenzweig, Erika Berman, Ivy, D. Dunbar, Widlitz, Allison, Doran, Aimee, Claussen, Lori R., Yung, Delphine, Abman, Steven H., Morganti, Adele, Nguyen, Ngoc, Barst, Robyn J.

“…This study investigated the long-term outcome of children with pulmonary arterial hypertension (PAH) treated with bosentan therapy, with or without concomitant…”
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Pharmacokinetic and clinical profile of a novel formulation of bosentan in children with pulmonary arterial hypertension: the FUTURE‐1 study by Beghetti, Maurice, Haworth, Sheila G., Bonnet, Damien, Barst, Robyn J., Acar, Philippe, Fraisse, Alain, Ivy, Dunbar D., Jais, Xavier, Schulze‐Neick, Ingram, Galiè, Nazzareno, Morganti, Adele, Dingemanse, Jasper, Kusic‐Pajic, Andjela, Berger, Rolf M. F.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Exposure to bosentan was lower in paediatric pulmonary arterial hypertension (PAH) patients treated with the…”
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A phase II study of bosentan, a dual endothelin receptor antagonist, as monotherapy in patients with stage IV metastatic melanoma by Kefford, Richard, Beith, Jane McNeil, Van Hazel, Guy Arthur, Millward, Michael, Trotter, James Marshall, Wyld, David Keith, Kusic, Rada, Shreeniwas, Revati, Morganti, Adele, Ballmer, Andrea, Segal, Eleonor, Nayler, Oliver, Clozel, Martine

“…There is no effective systemic therapy for disseminated metastatic melanoma. Data suggest that endothelin may play a role in pathophysiology of melanoma and…”
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Effects of long-term bosentan in children with pulmonary arterial hypertension. Commentary by ROSENZWEIG, Erika Berman, IVY, D. Dunbar, ADATIA, Ian, WIDLITZ, Allison, DORAN, Aimee, CLAUSSEN, Lori R, YUNG, Delphine, ABMAN, Steven H, MORGANTI, Adele, NGUYEN, Ngoc, BARST, Robyn J

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