Search Results - "Morgan, Sherif S"

Treatment of Unresectable and Metastatic Cutaneous Squamous Cell Carcinoma by Cranmer, Lee D., Engelhardt, Candace, Morgan, Sherif S.

“…Cutaneous squamous cell carcinoma (SCC) is an already common disorder with a rapidly increasing incidence. Treatment of early disease depends primarily on…”
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Roles for Endothelin Receptor B and BCL2A1 in Spontaneous CNS Metastasis of Melanoma by CRUZ-MUNOZ, William, JARAMILLO, Maria L, O'CONNOR-MCCOURT, Maureen D, KERBEL, Robert S, SHAN MAN, PING XU, BANVILLE, Myriam, COLLINS, Catherine, NANTEL, Andre, FRANCIA, Giulio, MORGAN, Sherif S, CRANMER, Lee D

“…Metastatic spread of melanoma to the central nervous system (CNS) is a common and devastating manifestation of disease progression, which, despite its clinical…”
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The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen by HOCKINGS, Jennifer K, THORNE, Patricia A, KEMP, Michael Q, MORGAN, Sherif S, SELMIN, Ornella, ROMAGNOLO, Donato F

“…In sporadic breast cancers, BRCA-1 expression is down-regulated in the absence of mutations in the BRCA-1 gene. This suggests that disruption of BRCA-1…”
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An Estrogen Receptor-α/p300 Complex Activates the BRCA-1 Promoter at an AP-1 Site That Binds Jun/Fos Transcription Factors: Repressive Effects of p53 on BRCA-1 Transcription by Jeffy, Brandon D., Hockings, Jennifer K., Kemp, Michael Q., Morgan, Sherif S., Hager, Jill A., Beliakoff, Jason, Whitesell, Luke J., Bowden, G. Timothy, Romagnolo, Donato F.

“…One of the puzzles in cancer predisposition is that women carrying BRCA-1 mutations preferentially develop tumors in epithelial tissues of the breast, ovary…”
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Vorinostat synergizes with ridaforolimus and abrogates the ridaforolimus-induced activation of AKT in synovial sarcoma cells by Morgan, Sherif S, Cranmer, Lee D

“…Curative treatments for patients with metastatic synovial sarcoma (SS) do not exist, and such patients have a poor prognosis. We explored combinations of…”
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Systematic Therapy for Unresectable or Metastatic Soft-Tissue Sarcomas: Past, Present, and Future by Morgan, Sherif S., Cranmer, Lee D.

“…Unresectable or metastatic disease occurs in 40% to 60% of soft-tissue sarcoma (STS) patients and portends a poor prognosis. For decades, doxorubicin has…”
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Quantitative histopathology identifies patients with thin melanomas who are at risk for metastases by Glazer, Evan S, Bartels, Peter H, Lian, Fangru, Kha, Stephanie T, Morgan, Sherif S, da Silva, Vinicius D, Yozwiak, Michael L, Bartels, Hubert G, Cranmer, Lee D, de Oliveira, Jefferson K, Alberts, David S, Warneke, James A, Krouse, Robert S

“…This small exploratory study was designed to test the hypothesis that thin melanoma lesions contain nuclei of two similar phenotypes, in different proportions…”
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Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene by Hockings, Jennifer K, Degner, Stephanie C, Morgan, Sherif S, Kemp, Michael Q, Romagnolo, Donato F

“…Increased estrogen level has been regarded to be a risk factor for breast cancer. However, estrogen has also been shown to induce the expression of the tumor…”
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Whole-brain radiation therapy in melanoma: an open question by Cranmer, Lee D, Jeter, Joanne M, Morgan, Sherif S, Hersh, Evan M, Stea, Baldassarre

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Serum protein acidic and rich in cysteine (SPARC) as a prognostic marker in soft tissue sarcomas by Morgan, Sherif S, Nagle, Raymond B, Cranmer, Lee D

“…Serum protein acidic and rich in cysteine (SPARC) is a matricellular secreted glycoprotein that performs several cellular functions and has been implicated in…”
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Identification of putative molecular targets in Merkel cell carcinoma by Morgan, Sherif S., Feldman, Rebecca, Cranmer, Lee D.

“…Abstract only…”
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Biomarker patterns of metastatic melanoma with implications for therapy by Cranmer, Lee D., Morgan, Sherif S., Feldman, Rebecca, Hamid, Omid

“…Abstract only…”
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Abstract 2820: Vorinostat abrogates ridaforolimus-induced activation of Akt in synovial sarcoma cells: A possible rationale for their synergism by Morgan, Sherif S., Cranmer, Lee D.

“…Background: Curative treatments for patients with metastatic synovial sarcoma (SS) do not exist and such patients have a poor prognosis. Previously, we…”
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Serum protein acidic and rich in cysteine (SPARC) as a prognostic marker in soft tissue sarcoma by Morgan, Sherif S., Nagle, Raymond B., Cranmer, Lee D.

“…Abstract only 10581 Background: SPARC is a matricellular secreted glycoprotein that performs several functions, including modulating cellular adhesion and…”
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A phase I study of pemetrexed in combination with docetaxel in advanced solid tumor patients by Cranmer, Lee D., Morgan, Sherif S., Bauland, Amy S, Burruel, Yrma, Cardenas, Jeanette S, Concannon, Terry, Schmidt, Kathy J, Snyder-Walker, Robin, Garland, Linda L.

“…Abstract only…”
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Abstract A242: A novel AKT inhibitor, PH427, prevents UVB-induced signaling in human squamous skin carcinomas by Meuillet, Emmanuelle J., Mash, Eugene A., Olsen, Erik, Moses, Sylvestor A., Morgan, Sherif S.

“…Non-melanoma skin cancers (NMSC) are a significant and increasing health problem in the United States that occur primarily on sun-exposed areas of the body and…”
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Whole-brain radiation therapy in melanoma: an open question – Authors' reply by Chang, Eric L, Hwu, Patrick

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Involvement of a specificity proteins-binding element in regulation of basal and estrogen-induced transcription activity of the BRCA1gene by Hockings, Jennifer K, Degner, Stephanie C, Morgan, Sherif S, Kemp, Michael Q, Romagnolo, Donato F

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The bile acid, deoxycholic acid, modulates IGF-IR function in colon cancer cells by Morgan, Sherif S

“…Deoxycholic acid (DCA) is a secondary bile acid postulated to be involved in the etiology and the progression of colorectal cancer, but its specific mechanisms…”
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An Estrogen Receptor-α/p300 Complex Activates the BRCA-1 Promoter at an AP-1 Site That Binds Jun/Fos Transcription Factors: Repressive Effects of p53 on BRCA-1 Transcription1 by Jeffy, Brandon D, Hockings, Jennifer K, Kemp, Michael Q, Morgan, Sherif S, Hager, Jill A, Beliakoff, Jason, Whitesell, Luke J, Bowden, G. Timothy, Romagnolo, Donato F

“…One of the puzzles in cancer predisposition is that women carrying BRCA-1 mutations preferentially develop tumors in epithelial tissues of the breast and…”
Get full text