Search Results - "Morgan, Marc A. J."

Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation by Morgan, Marc A. J., Shilatifard, Ali

“…Histone-modifying enzymes are implicated in the control of diverse DNA-templated processes including gene expression. Here, we outline historical and current…”
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Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation by Mould, Arne W, Morgan, Marc A J, Nelson, Andrew C, Bikoff, Elizabeth K, Robertson, Elizabeth J

“…The neonatal intestine is a very complex and dynamic organ that must rapidly adapt and remodel in response to a barrage of environmental stimuli during the…”
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Blimp-1/Prdm1 Alternative Promoter Usage during Mouse Development and Plasma Cell Differentiation by Morgan, Marc A. J., Magnusdottir, Erna, Kuo, Tracy C., Tunyaplin, Chai, Harper, James, Arnold, Sebastian J., Calame, Kathryn, Robertson, Elizabeth J., Bikoff, Elizabeth K.

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The PR/SET Domain Zinc Finger Protein Prdm4 Regulates Gene Expression in Embryonic Stem Cells but Plays a Nonessential Role in the Developing Mouse Embryo by Bogani, Debora, Morgan, Marc A. J., Nelson, Andrew C., Costello, Ita, McGouran, Joanna F., Kessler, Benedikt M., Robertson, Elizabeth J., Bikoff, Elizabeth K.

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The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice by Morgan, Marc A J, Muller, Pari S S, Mould, Arne, Newland, Stephen A, Nichols, Jennifer, Robertson, Elizabeth J, Cooke, Anne, Bikoff, Elizabeth K

“…The spontaneous destruction of insulin producing pancreatic beta cells in non-obese diabetic (NOD) mice provides a valuable model of type 1 diabetes. As in…”
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Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription by Morgan, Marc A J, Shilatifard, Ali

“…The past three decades have yielded a wealth of information regarding the chromatin regulatory mechanisms that control transcription. The "histone code"…”
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ELOA3 : A primate-specific RNA polymerase II elongation factor encoded by a tandem repeat gene cluster by Morgan, Marc A J, Mohammad Parast, Saeid, Iwanaszko, Marta, Aoi, Yuki, Yoo, DongAhn, Dumar, Zachary J, Howard, Benjamin C, Helmin, Kathryn A, Liu, Qianli, Thakur, William R, Zeidner, Jacob M, Singer, Benjamin D, Eichler, Evan E, Shilatifard, Ali

“…The biological role of the repetitive DNA sequences in the human genome remains an outstanding question. Recent long-read human genome assemblies have allowed…”
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Pcp4l1 contains an auto-inhibitory element that prevents its IQ motif from binding to calmodulin by Morgan, Marc A. J., Morgan, James I.

“…J. Neurochem. (2012) 121, 843–851. Purkinje cell protein 4‐like 1 (Pcp4l1) is a small neuronal IQ motif protein closely related to the calmodulin‐binding…”
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Alternative Splicing Regulates Prdm1/Blimp-1 DNA Binding Activities and Corepressor Interactions by Morgan, Marc A. J., Mould, Arne W., Li, Li, Robertson, Elizabeth J., Bikoff, Elizabeth K.

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A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer by Morgan, Marc A J, Popova, Irina K, Vaidya, Anup, Burg, Jonathan M, Marunde, Matthew R, Rendleman, Emily J, Dumar, Zachary J, Watson, Rachel, Meiners, Matthew J, Howard, Sarah A, Khalatyan, Natalia, Vaughan, Robert M, Rothbart, Scott B, Keogh, Michael-C, Shilatifard, Ali

“…Mutations in the chromatin regulator cause the human neurodevelopmental disorder Chung-Jansen syndrome, while alterations in expression are linked to cancer…”
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A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation by Morgan, Marc A J, Rickels, Ryan A, Collings, Clayton K, He, Xiaolin, Cao, Kaixiang, Herz, Hans-Martin, Cozzolino, Kira A, Abshiru, Nebiyu A, Marshall, Stacy A, Rendleman, Emily J, Sze, Christie C, Piunti, Andrea, Kelleher, Neil L, Savas, Jeffrey N, Shilatifard, Ali

“…Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene -regulatory sequences such as promoters and enhancers. Here we identify an…”
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Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta by Mould, Arne, Morgan, Marc A J, Li, Li, Bikoff, Elizabeth K, Robertson, Elizabeth J

“…Developmental arrest of Blimp1/Prdm1 mutant embryos at around embryonic day 10.5 (E10.5) has been attributed to placental disturbances. Here we investigate…”
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CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism by Piunti, Andrea, Smith, Edwin R, Morgan, Marc A J, Ugarenko, Michal, Khaltyan, Natalia, Helmin, Kathryn A, Ryan, Caila A, Murray, David C, Rickels, Ryan A, Yilmaz, Bahar D, Rendleman, Emily J, Savas, Jeffrey N, Singer, Benjamin D, Bulun, Serdar E, Shilatifard, Ali

“…Using biochemical characterization of fusion proteins associated with endometrial stromal sarcoma, we identified JAZF1 as a new subunit of the NuA4…”
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Pcp4I1 contains an auto-inhibitory element that prevents its IQ motif from binding to calmodulin by MORGAN, Marc A. J, MORGAN, James I

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Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation: e1005375 by Mould, Arne W, Morgan, Marc AJ, Nelson, Andrew C, Bikoff, Elizabeth K, Robertson, Elizabeth J

“…The neonatal intestine is a very complex and dynamic organ that must rapidly adapt and remodel in response to a barrage of environmental stimuli during the…”
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