Search Results - "Morgan, Magdalena"
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Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity
Published in Cell metabolism (05-12-2012)“…Mice lacking the Jak tyrosine kinase member Tyk2 become progressively obese due to aberrant development of Myf5+ brown adipose tissue (BAT). Tyk2 RNA levels in…”
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The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes
Published in PloS one (21-12-2015)“…The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes…”
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P2Y12 receptor expression is a critical determinant of functional responsiveness to ATX’s MORFO domain
Published in Purinergic signalling (01-06-2012)“…In the central nervous system, the formation of the myelin sheath and the differentiation of the myelinating cells, namely oligodendrocytes, are regulated by…”
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The JAK kinase Tyk2 and the Signal Transducer and Activator of Transcription 3 (Stat3) are required for Brown Adipose Tissue Differentiation
Published in The FASEB journal (01-04-2012)“…Abstract only Type II diabetes, cardiovascular disease, non‐alcoholic fatty liver disease and Alzheimer's disease are some of the numerous disorders associated…”
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