Search Results - "Morgan, LR"

Abstract CT119: Early phase I clinical trial results for 4-demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) plus radiation in cancers involving the CNS by Morgan, LR, Mahmood, T, Weiner, R S., Kawauchi, R, Bhandari, M, Devisitty, K, Herman, J, Summe, R, Ware, ML, Friedlander, P, Rodgers, AH

“…Abstract Purpose:4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) is a poly-chlorinated pyridine cholesteryl carbonate with a mechanism of action…”
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Abstract CT225: A phase I cancer clinical trial for 4-demethyl-4cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) IND 68.876 by Weiner, Roy S., Friedlander, Philip, Gordon, Craig, Saenger, Yvonne, Mohmood, Tallat, Ware, Marcus, Rogers, AH, Bastian, Gerard, Urien, S, Morgan, LR

“…Abstract Purpose: 4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) is a poly-chlorinated pyridine cholesteryl carbonate whose MOA is via…”
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Abstract CT218: Results from the early cancer clinical trials for 4-demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) by Weiner, Roy S., Friedlander, P, Mahmood, T, Hormigo, Adilia, Gordon, C, Saenger, Y, Ware, ML, Thirukonda, VK, Patel, VM, Cosgriff, TJ, Rodgers, AH, Morgan, LR, Bastian, G

“…Abstract Purpose: 4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN), is a poly-chlorinated pyridine cholesteryl carbonate whose MOA is via…”
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Abstract CT129: Phase II clinical trial results for 4-demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in NSCLC involving the CNS by Weiner, Roy S., Mahmood, T, Gordon, C, Ware, ML, Morgan, LR, Cosgriff, TM, Rodgers, AH, Bastian, G, Kawauchi, R, Matrana, M, Zou, J-J

“…Abstract Background: 4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) is a poly-chlorinated pyridine cholesteryl carbonate with a MOA via…”
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Anticancer activity for 4,4′-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) analogues and Their abilities to interact with lymphoendothelial cell surface markers by Morgan, Lee Roy, Jursic, Branko S., Hooper, Catherine L., Neumann, Donna M., Thangaraj, Kanappan, LeBlanc, Blaise

“…The structure of the anticancer agent 4,4′-dihydroxybenzophenone-2,4-dinitrophenylhydrazone ( A-007) has been modified through SAR and by incorporating…”
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Design, Synthesis, and Anticancer Properties of 4,4‘-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone and Analogues by Morgan, Lee Roy, Thangaraj, Kanappan, LeBlanc, Blaise, Rodgers, Andrew, Wolford, Lionel T, Hooper, Catherine L, Fan, Dominic, Jursic, Branko S

“…4,4‘-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) has recently completed a phase I clinical trial in advanced cancer with minimal toxicity, and…”
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4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) : a topical treatment for cutaneous metastases from malignant cancers by EILENDER, David, LORUSSO, Patricia, THOMAS, Leonard, MCCORMICK, Catherine, RODGERS, Andrew H, HOOPER, Catherine L, TORNYOS, Karl, KREMENTZ, Edward T, PARKER, Steven, MORGAN, Lee Roy

“…This study is to document the activity and acceptability for a new topical agent, A-007, in the treatment of cutaneous metastases from cancer. This is a…”
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Comparative preclinical toxicology and pharmacology of isophosphoramide mustard, the active metabolite of ifosfamide by GERMANN, N, URIEN, S, RODGERS, Andrew H, RATTERREE, Marion, STRUCK, Robert F, WAUD, William R, SEROTA, David G, BASTIAN, Gerard, JURSIC, Branko S, MORGAN, Lee Roy

“…Isophosphoramide mustard (IPM) is the cytotoxic alkylating metabolite of Ifosfamide (IFOS). IPM is being readied for a phase I clinical trial. In the present…”
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High-performance liquid chromatographic determination of 4,4′-dihydroxybenzophenone-2,4-dinitrophenylhydrazone in plasma by Rodgers, Andrew H., Subramanian, Sandhya, Morgan, Lee Roy

“…An analytical method has been developed for the determination of 4,4′-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (I, trade name A-007) in plasma. Plasma…”
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Gas chromatography–electron ionization mass spectrometry and liquid chromatography–electrospray tandem mass spectrometry for determination of impurities in the anti-cancer drug isophosphoramide mustard by Cole, Richard B, Chou, Chau-Wen, Boué, Stephen M, LeBlanc, Blaise W, Rodgers, Andrew H, Struck, Robert F, Morgan, Lee Roy

“…Isophosphoramide mustard (IPM) is known to have substantial anti-cancer activities in various animal models. Liquid chromatography–electrospray mass…”
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Anticancer Properties for 4,4′-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007)/3,7-Diaminophenothiazin-5-ium Double Salts by Morgan, Lee Roy, Rodgers, Andrew H, LeBlanc, Blaise W, Boué, Steven M, Yang, Ying, Jursic, Branko S, Cole, Richard B

“…4,4′-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) formed stable double salts with phenothiazin-5-ium salts ( 2a– d), which have improved in vitro…”
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Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolite of penclomedine by STRUCK, Robert F, TIWARI, Anita, FRIEDMAN, Henry S, KEIR, Steven, MORGAN, Lee Roy, WAUD, William R

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Megestrol acetate v tamoxifen in advanced breast cancer in postmenopausal patients by Morgan, L R

“…One hundred six postmenopausal patients with advanced breast cancer received megestrol acetate or tamoxifen as primary therapy. Response to therapy was…”
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Exposure to Male Siblings Facilitates the Response to Estradiol in Sexually Naive Female Prairie Voles by Morgan, Leann R, Hite, Renita F, Cushing, Bruce S

“…Morgan, L. R., R. F. Hite and B. S. Cushing. Exposure to male siblings facilitates the response to estradiol in sexually naive female prairie voles. Physiol…”
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Comparative dermal pharmacology and toxicology of 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) in rodents and primates by Morgan, L R, Rodgers, A H, Hooper, C L, Ratterree, M, Soike, K, Serota, D, Beis, R, Schwartz, S L

“…4,4'-Dihydroxybenzophenone-2,4-ditrophenylhydrazone (A-007) has demonstrated anticancer activities, when administered topically to patients with metastatic…”
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How to Stop Nurse Migration by Morgan, Linda R.

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Comparative preclinical toxicology and pharmacology of 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) in vitro and in rodents and primates by Morgan, L R, Rodgers, A H, Fan, D, Soike, K, Ratterree, M, Sartin, B W, Harrison, T J

“…4,4'-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) is being evaluated for its anticancer activities. Acute, subacute and chronic oral, dermal,…”
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Adoptive immunotherapy of advanced renal cell cancer using PHA-stimulated autologous lymphocytes by Morgan, L R, Krementz, E T, Fan, S W, Fan, D

“…Patients with advanced renal cell carcinoma, previously failed maximal treatment with standard chemo-hormonal-radiation therapies, were treated with plant…”
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N-acetylcysteine: its bioavailability and interaction with ifosfamide metabolites by Morgan, L R, Holdiness, M R, Gillen, L E

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Ifosfamide in the treatment of extensive non-oat cell carcinoma of the lung by Costanzi, J J, Morgan, L R, Hokanson, J

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