Search Results - "Morgan, A E"
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1
The role of DNA methylation in ageing and cancer
Published in Proceedings of the Nutrition Society (01-11-2018)“…The aim of the present review paper is to survey the literature related to DNA methylation, and its association with cancer and ageing. The review will outline…”
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2
Cholesterol Metabolism: A Review of How Ageing Disrupts the Biological Mechanisms Responsible for its Regulation
Published in Ageing research reviews (01-05-2016)“…Highlights • Ageing dysregulates cholesterol metabolism via a number of mechanisms. • Changes to the gut microbiome may play a role in dysregulating…”
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3
Urban water metabolism indicators derived from a water mass balance – Bridging the gap between visions and performance assessment of urban water resource management
Published in Water research (Oxford) (01-10-2017)“…Improving resource management in urban areas has been enshrined in visions for achieving sustainable urban areas, but to date it has been difficult to quantify…”
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4
Consensus guidelines for management of patellofemoral instability
Published in The Knee (01-03-2021)“…The aim of this consensus process was to provide robust national guidelines to assist with decision making with regards to surgical management of…”
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5
Microscopic computed tomography imaging of the cerebral circulation in mice: Feasibility and pitfalls
Published in Synapse (New York, N.Y.) (01-08-2008)“…This study evaluates the utility and practical limitations of microcomputerized X‐ray tomography (CT) as a research tool for examination of the cerebral…”
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6
Effects of the epibiotic heterotrich ciliate Mirofolliculina limnoriae and of moulting on faecal pellet production by the wood-boring isopods, Limnoria tripunctata and Limnoria quadripunctata
Published in Journal of experimental marine biology and ecology (11-07-2006)“…The heterotrich ciliate Mirofolliculina limnoriae occurs in an obligate association with wood-boring species of the isopod Limnoria. It attaches to the dorsal…”
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7
Investigating cholesterol metabolism and ageing using a systems biology approach
Published in Proceedings of the Nutrition Society (01-08-2017)“…CVD accounted for 27 % of all deaths in the UK in 2014, and was responsible for 1·7 million hospital admissions in 2013/2014. This condition becomes…”
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8
The CXCR4/SDF-1 chemokine axis: a potential therapeutic target for bone metastases?
Published in Current pharmaceutical design (01-04-2010)“…Chemokines and chemokine receptors play diverse roles in homeostasis. The chemokine stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 have critical…”
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9
Mathematically modelling the dynamics of cholesterol metabolism and ageing
Published in BioSystems (01-07-2016)“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the UK. This condition becomes increasingly prevalent during ageing; 34.1% and…”
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10
Cost‐effective approach to the diagnostic workup of B cell lymphoproliferative disorders via optimal integration of flow cytometric data
Published in International journal of laboratory hematology (01-04-2017)“…Summary Introduction The workup of lymphoproliferative disorders (LPDs) involves the combined use of flow cytometry (FC) and immunohistochemistry (IHC). This…”
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11
Antitermination mechanisms in rRNA operons of Escherichia coli
Published in Journal of bacteriology (01-10-1986)“…In this review the author assesses the available information about antitermination mechanisms in rRNA operons (rrn operons) of Escherichia coli . The reader is…”
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12
Characterization and molecular cloning of a proenzyme form of a ribosome-inactivating protein from maize. Novel mechanism of proenzyme activation by proteolytic removal of a 2.8-kilodalton internal peptide segment
Published in The Journal of biological chemistry (05-12-1991)“…Ribosome-inactivating proteins (RIPs) are a widely distributed family of plant enzymes that are remarkably potent catalytic inactivators of eukaryotic protein…”
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13
Identification of a single base change in ribosomal RNA leading to erythromycin resistance
Published in The Journal of biological chemistry (25-04-1992)“…The molecular basis of a mutation conferring an erythromycin-resistance phenotype was explored, as an approach to the role of 23 S rRNA in the…”
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14
Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia
Published in Development (Cambridge) (15-07-2003)“…In humans and mice, mutations in Hoxa13 cause malformation of limb and genitourinary (GU) regions. In males, one of the most common GU malformations associated…”
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15
Involvement of capsaicin-sensitive nerves in regulating the hormone and glucose metabolic response to endotoxin
Published in The American journal of physiology (01-08-1997)“…This study investigated the role that sensory nerves play in mediating the hormone and glucose metabolic response to endotoxin [lipopolysaccharide (LPS)]…”
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Overlapping Functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 Nucleases in DNA Metabolism
Published in Genetics (Austin) (01-12-2001)“…MRE11 functions in several aspects of DNA metabolism, including meiotic recombination, double-strand break repair, and telomere maintenance. Although the…”
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Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens:: A microdialysis study
Published in European journal of pharmacology (16-07-1997)“…In this study, we examined the ability of a single injection of cocaine (20 mg/kg, i.p.) to augment extracellular dopamine levels in the nucleus accumbens two…”
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18
The effect of intercondylar notchplasty on the patellofemoral articulation
Published in The American journal of sports medicine (01-11-1996)“…Using pressure-sensitive film, we measured the patellofemoral contact areas and pressures after increasing degrees of notchplasty in eight fresh-frozen…”
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19
ON THE CHANGES CAUSED BY AN UNDERLYING COUPLED ROTATIONAL MOTION ON THE NATURAL FREQUENCIES OF A MASS–SPRING SYSTEM
Published in Journal of sound and vibration (07-09-2000)“…When a system of N masses, linked together by springs, is disturbed from its static equilibrium position, then it will vibrate in a manner characterized by the…”
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20
High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity
Published in Oncogene (08-05-2003)“…The expression of cutaneous fatty acid-binding protein (C-FABP) in prostate tissues was examined by immunohistochemistry. Among the 76 cases, all seven (100%)…”
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