Search Results - "Morffy, Nicholas"
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Old Town Roads: routes of auxin biosynthesis across kingdoms
Published in Current opinion in plant biology (01-06-2020)“…•Auxin is produced and sensed by land plants, some algae, and some bacteria.•The primary route of auxin production in land plants is likely present in green…”
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Smoke and Hormone Mirrors: Action and Evolution of Karrikin and Strigolactone Signaling
Published in Trends in genetics (01-03-2016)“…Karrikins and strigolactones are two classes of butenolide molecules that have diverse effects on plant growth. Karrikins are found in smoke and strigolactones…”
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SMAX1-LIKE/D53 Family Members Enable Distinct MAX2-Dependent Responses to Strigolactones and Karrikins in Arabidopsis
Published in The Plant cell (01-11-2015)“…The plant hormones strigolactones and smoke-derived karrikins are butenolide signals that control distinct aspects of plant development. Perception of both…”
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Functional redundancy in the control of seedling growth by the karrikin signaling pathway
Published in Planta (01-06-2016)“…Strigolactones (SLs) are plant hormones with butenolide moieties that control diverse aspects of plant growth, including shoot branching. Karrikins (KARs) are…”
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Direct photoresponsive inhibition of a p53-like transcription activation domain in PIF3 by Arabidopsis phytochrome B
Published in Nature communications (23-09-2021)“…Photoactivated phytochrome B (PHYB) binds to antagonistically acting PHYTOCHROME-INTERACTING transcription FACTORs (PIFs) to regulate hundreds of light…”
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Locally Sourced: Auxin Biosynthesis and Transport in the Root Meristem
Published in Developmental cell (05-11-2018)“…Localized maxima of the plant hormone auxin are crucial to root development and meristem maintenance. In this issue of Developmental Cell, Brumos et al. used…”
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Regulation of AUXIN RESPONSE FACTOR condensation and nucleo-cytoplasmic partitioning
Published in Nature communications (11-07-2022)“…Auxin critically regulates plant growth and development. Auxin-driven transcriptional responses are mediated through the AUXIN RESPONSE FACTOR (ARF) family of…”
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Plant promoter-proximal pausing?
Published in Nature plants (01-07-2021)“…A study of a synthetic auxin response circuit in a heterologous system suggests that hindrance of Mediator complex function by the co-repressor TOPLESS may…”
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Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases
Published in PloS one (15-07-2014)“…Protein neddylation is involved in a wide variety of cellular processes. Here we show that the DNA damage response is perturbed in cells inactivated with an E2…”
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Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model
Published in Journal of neurotrauma (01-01-2014)“…Soluble amyloid-beta (Aβ) oligomers are hypothesized to be the pathogenic species in Alzheimer's disease (AD), and increased levels of oligomers in the brain…”
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Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants
Published in Nature communications (18-01-2024)“…The Arabidopsis thaliana DREB2A transcription factor interacts with the negative regulator RCD1 and the ACID domain of subunit 25 of the transcriptional…”
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Structural Aspects of Auxin Signaling
Published in Cold Spring Harbor perspectives in biology (01-01-2022)“…Auxin signaling regulates growth and developmental processes in plants. The core of nuclear auxin signaling relies on just three components: TIR1/AFBs,…”
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Structure-Function Analysis of SMAX1 Reveals Domains That Mediate Its Karrikin-Induced Proteolysis and Interaction with the Receptor KAI2
Published in The Plant cell (01-08-2020)“…Karrikins (KARs) are butenolides found in smoke that can influence germination and seedling development of many plants. The KAR signaling mechanism is…”
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ARF19 Condensation in the Arabidopsis Stomatal Lineage
Published in microPublication biology (2023)“…The phytohormone auxin regulates nearly every aspect of plant development. Transcriptional responses to auxin are driven by the activities of the AUXIN…”
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Identification of plant transcriptional activation domains
Published in Nature (London) (01-08-2024)“…Gene expression in Arabidopsis is regulated by more than 1,900 transcription factors (TFs), which have been identified genome-wide by the presence of…”
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Identification of plant transcriptional activation domains
Published in Nature (London) (01-08-2024)“…Gene expression in Arabidopsis is regulated by more than 1,900 transcription factors (TFs), which have been identified genome-wide by the presence of…”
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Structure-Function Analysis of SMAX1 Reveals Domains That Mediate Its Karrikin-Induced Proteolysis and Interaction with the Receptor KAI2
Published in The Plant cell (03-08-2020)“…Karrikins (KARs) are butenolides found in smoke that can influence germination and seedling development of many plants. The KAR signaling mechanism is…”
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Prediction and functional characterization of transcriptional activation domains
Published in 2023 57th Annual Conference on Information Sciences and Systems (CISS) (22-03-2023)“…Gene expression is induced by transcription factors (TFs) through their activation domains (ADs). However, ADs are unconserved, intrinsically disordered…”
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