Search Results - "Moresco, Rosa M."

Effects of Metformin as Add-On Therapy against Glioblastoma: An Old Medicine for Novel Oncology Therapeutics by Guarnaccia, Laura, Navone, Stefania E, Masseroli, Matteo M, Balsamo, Melissa, Caroli, Manuela, Valtorta, Silvia, Moresco, Rosa M, Campanella, Rolando, Schisano, Luigi, Fiore, Giorgio, Galiano, Valentina, Garzia, Emanuele, Appiani, Giuseppe C, Locatelli, Marco, Riboni, Laura, Marfia, Giovanni

“…Glioblastoma is the most aggressive primary brain malignancy in adults, with a poor prognosis of about 14 months. Recent evidence ascribed to metformin (MET),…”
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A ROI-based quantitative pipeline for 18F-FDG PET metabolism and pCASL perfusion joint analysis: Validation of the 18F-FDG PET line by Cerina, Valeria, Crivellaro, Cinzia, Morzenti, Sabrina, Pozzi, Federico E., Bigiogera, Vittorio, Jonghi-Lavarini, Lorenzo, Moresco, Rosa M., Basso, Gianpaolo, De Bernardi, Elisabetta

“…In Mild Cognitive Impairment (MCI), the study of brain metabolism, provided by 18F-FluoroDeoxyGlucose Positron Emission Tomography (18F-FDG PET) can be…”
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Endovascular administration of magnetized nanocarriers targeting brain delivery after stroke by Grayston, Alba, Zhang, Yajie, Garcia-Gabilondo, Miguel, Arrúe, Mercedes, Martin, Abraham, Kopcansky, Peter, Timko, Milan, Kovac, Jozef, Strbak, Oliver, Castellote, Laura, Belloli, Sara, Moresco, Rosa M, Picchio, Maria, Roig, Anna, Rosell, Anna

“…The increasing use of mechanical thrombectomy in stroke management has opened the window to local intraarterial brain delivery of therapeutic agents. In this…”
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Acute Inescapable Stress Rapidly Increases Synaptic Energy Metabolism in Prefrontal Cortex and Alters Working Memory Performance by Musazzi, Laura, Sala, Nathalie, Tornese, Paolo, Gallivanone, Francesca, Belloli, Sara, Conte, Alessandra, Di Grigoli, Giuseppe, Chen, Fengua, Ikinci, Ayşe, Treccani, Giulia, Bazzini, Chiara, Castiglioni, Isabella, Nyengaard, Jens R, Wegener, Gregers, Moresco, Rosa M, Popoli, Maurizio

“…Abstract Brain energy metabolism actively regulates synaptic transmission and activity. We have previously shown that acute footshock (FS)-stress induces fast…”
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Basal ganglia and language: phonology modulates dopaminergic release by TETTAMANTI, Marco, MORO, Andrea, MESSA, Cristina, MORESCO, Rosa M, RIZZO, Giovanna, CARPINELLI, Assunta, MATARRESE, Mario, FAZIO, Ferruccio, PERANI, Daniela

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Molecular imaging of neuroinflammation in preclinical rodent models using positron emission tomography by Gargiulo, Sara, Coda, Anna R, Panico, Mariarosaria, Gramanzini, Matteo, Moresco, Rosa M, Chalon, Sylvie, Pappatà, Sabina

“…Neuroinflammation (NI) is an adaptive response to different noxious stimuli, involving microglia, astrocytes and peripheral immune cells. NI is a hallmark of…”
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Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling by Alberghina, Lilia, Gaglio, Daniela, Gelfi, Cecilia, Moresco, Rosa M, Mauri, Giancarlo, Bertolazzi, Paola, Messa, Cristina, Gilardi, Maria C, Chiaradonna, Ferdinando, Vanoni, Marco

“…Systems Biology holds that complex cellular functions are generated as system-level properties endowed with robustness, each involving large networks of…”
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Characterization of preclinical models of prostate cancer using PET-based molecular imaging by Belloli, Sara, Jachetti, Elena, Moresco, Rosa M., Picchio, Maria, Lecchi, Michela, Valtorta, Silvia, Freschi, Massimo, Michelini, Rodrigo Hess, Bellone, Matteo, Fazio, Ferruccio

“…Purpose Transgenic adenocarcinoma of the mouse prostate (TRAMP) mice spontaneously develop hormone-dependent and hormone-independent prostate cancer (PC) that…”
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11C-Labeling of N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]arylcarboxamide Derivatives and Evaluation as Potential Radioligands for PET Imaging of Dopamine D3 Receptors by Turolla, Elia A, Matarrese, Mario, Belloli, Sara, Moresco, Rosa M, Simonelli, Pasquale, Todde, Sergio, Fazio, Ferruccio, Magni, Fulvio, Kienle, Marzia Galli, Leopoldo, Marcello, Berardi, Francesco, Colabufo, Nicola A, Lacivita, Enza, Perrone, Roberto

“…The selective dopamine D3 receptor ligands N-4-[4-[(2,3-dichlorophenyl)piperazin-1-yl]butyl]1-methoxy-2-naphthalencarboxamide (1) and…”
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3D Spatial resolution proprieties of Molecubes β-Cube: characterization with different isotopes by Presotto, Luca, Spangler-Bickell, Matthew, Belloli, Sara, Moresco, Rosa M., Picchio, Maria, Gilardi, Maria C., Gianolli, L., Bettinardi, Valentino

“…The preclinical β-Cube PET scanner features a design with monolithic crystal detectors and DOI estimation. Images are reconstructed with a 3D list mode…”
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[11C]RN5: A new agent for the in vivo imaging of myocardial α1-adrenoceptors by Matarrese, Mario, Moresco, Rosa M, Romeo, Giuseppe, Turolla, Elia A, Simonelli, Pasquale, Todde, Sergio, Belloli, Sara, Carpinelli, Assunta, Magni, Fulvio, Russo, Filippo, Galli Kienle, Marzia, Fazio, Ferruccio

“…The radiolabelling with the positron-emitter Carbon-11 and the biological evaluation in rats of…”
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A ROI-based quantitative pipeline for 18 F-FDG PET metabolism and pCASL perfusion joint analysis: Validation of the 18 F-FDG PET line by Cerina, Valeria, Crivellaro, Cinzia, Morzenti, Sabrina, Pozzi, Federico E, Bigiogera, Vittorio, Jonghi-Lavarini, Lorenzo, Moresco, Rosa M, Basso, Gianpaolo, De Bernardi, Elisabetta

“…In Mild Cognitive Impairment (MCI), the study of brain metabolism, provided by 18F-FluoroDeoxyGlucose Positron Emission Tomography ( F-FDG PET) can be…”
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Myocardial glucose uptake evaluated by positron emission tomography and fluorodeoxyglucose during hyperglycemic clamp in IDDM patients : role of free fatty acid and insulin levels by MONTI, L. D, LUCIGNANI, G, LANDONI, C, MORESCO, R. M, PIATTI, P, STEFANI, I, POZZA, G, FAZIO, F

“…Myocardial and whole-body glucose metabolism was assessed in 19 insulin-dependent diabetes mellitus (IDDM) patients. A hyperglycemic clamp was performed 1) in…”
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A systems biology road map for the discovery of drugs targeting cancer cell metabolism by Alberghina, Lilia, Gaglio, Daniela, Moresco, Rosa Maria, Gilardi, Maria Carla, Messa, Cristina, Vanoni, Marco

“…Despite their different histological and molecular properties, different types of cancers share few essential functional alterations. Some of these cancer…”
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Basal ganglia and language: phonology modulates dopaminergic release by Tettamanti, Marco, Moro, Andrea, Messa, Cristina, Moresco, Rosa M, Rizzo, Giovanna, Carpinelli, Assunta, Matarrese, Mario, Fazio, Ferruccio, Perani, Daniela

“…Basal ganglia have been implicated in syntactic and phonological processes, but direct evidence has been scarce. Here, we used [C]raclopride and positron…”
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Radiosynthesis and Preliminary Biological Evaluation of [18F]VC701, a Radioligand for Translocator Protein by Di Grigoli, Giuseppe, Monterisi, Cristina, Belloli, Sara, Masiello, Valeria, Politi, Letterio Salvatore, Valenti, Salvatore, Paolino, Marco, Anzini, Maurizio, Matarrese, Mario, Cappelli, Andrea, Moresco, Rosa Maria

“…Positron emission tomography (PET) can be used to monitor in vivo translocator protein (TSPO) expression by using specific radioligands. Recently, several…”
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11 C-Labeling of N -[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]arylcarboxamide Derivatives and Evaluation as Potential Radioligands for PET Imaging of Dopamine D 3 Receptors by Turolla, Elia A., Matarrese, Mario, Belloli, Sara, Moresco, Rosa M., Simonelli, Pasquale, Todde, Sergio, Fazio, Ferruccio, Magni, Fulvio, Kienle, Marzia Galli, Leopoldo, Marcello, Berardi, Francesco, Colabufo, Nicola A., Lacivita, Enza, Perrone, Roberto

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[11C]RN5: a new agent for the in vivo imaging of myocardial alpha1-adrenoceptors by Matarrese, Mario, Moresco, Rosa M, Romeo, Giuseppe, Turolla, Elia A, Simonelli, Pasquale, Todde, Sergio, Belloli, Sara, Carpinelli, Assunta, Magni, Fulvio, Russo, Filippo, Galli Kienle, Marzia, Fazio, Ferruccio

“…The radiolabelling with the positron-emitter Carbon-11 and the biological evaluation in rats of…”
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Measurement of Regional Cerebral Glucose Utilization with Fluorine-18-FDG and PET in Heterogeneous Tissues: Theoretical Considerations and Practical Procedure by Lucignani, Giovanni, Schmidt, Kathleen C, Moresco, Rosa M, Striano, Giuseppe, Colombo, Fabio, Sokoloff, Louis, Fazio, Ferruccio

“…Functional tissue heterogeneity, i.e., inclusion of tissues with different rates of blood flow and metabolism within a single region of interest, is an…”
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Synthesis and Biodistribution of (R,S)-[O-Methyl-11C]-1-[3-(5-Methoxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl]-4-Phenylpiperazine (PNU-157760), A Putative Radioligand for 5-HT1AReceptors by Matarrese, Mario, Soloviev, Dmitrij V., Moresco, Rosa M., Ferri, Valentino, Simonelli, Pasquale, Magni, Fulvio, Colombo, Diego, Todde, Sergio, Carpinelli, Assunta, Fazio, Ferruccio, Kienle, Marzia Galli

“…Racemic 1-[3-(5-methoxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl]-4-phenylpiperazine (PNU-157760) was labeled with carbon-11 (t1/2= 20.4 min) as a putative…”
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