Search Results - "Moresco, R. M."

Development of a new toolbox for mouse PET–CT brain image analysis fully based on CT images and validation in a PD mouse model by Presotto, L., Bettinardi, V., Mercatelli, D., Picchio, M., Morari, M., Moresco, R. M., Belloli, Sara

“…Automatic analysis toolboxes are popular in brain image analysis, both in clinical and in preclinical practices. In this regard, we proposed a new toolbox for…”
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In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416 by Moresco, R M, Todde, S, Belloli, S, Simonelli, P, Panzacchi, A, Rigamonti, M, Galli-Kienle, M, Fazio, F

“…The aim of this study was to evaluate the suitability of [11C]SCH442416 for the in vivo imaging of adenosine A2A receptors. In rats and Macaca nemestrina, we…”
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Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts by Agnusdei, V, Minuzzo, S, Frasson, C, Grassi, A, Axelrod, F, Satyal, S, Gurney, A, Hoey, T, Seganfreddo, E, Basso, G, Valtorta, S, Moresco, R M, Amadori, A, Indraccolo, S

“…T-acute lymphoblastic leukemia (T-ALL) is characterized by several genetic alterations and poor prognosis in about 20–25% of patients. Notably, about 60% of…”
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In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease by Iannaccone, S, Cerami, C, Alessio, M, Garibotto, V, Panzacchi, A, Olivieri, S, Gelsomino, G, Moresco, R.M, Perani, D

“…Abstract Background Reactive microgliosis, hallmark of neuroinflammation, may contribute to neuronal degeneration, as shown in several neurodegenerative…”
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Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration by Belloli, S., Moresco, R.M., Matarrese, M., Biella, G., Sanvito, F., Simonelli, P., Turolla, E., Olivieri, S., Cappelli, A., Vomero, S., Galli-Kienle, M., Fazio, F.

“…The peripheral-type benzodiazepine receptors (PBRs) are only minimally expressed in normal brain parenchyma, where they are primarily localized in glial cells…”
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From cancer metabolism to new biomarkers and drug targets by Chiaradonna, F., Moresco, R.M., Airoldi, C., Gaglio, D., Palorini, R., Nicotra, F., Messa, C., Alberghina, L.

“…Great interest is presently given to the analysis of metabolic changes that take place specifically in cancer cells. In this review we summarize the…”
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Differential distribution of striatal [123I]beta-CIT in Parkinson's disease and progressive supranuclear palsy, evaluated with single-photon emission tomography by Messa, C, Volonté, M A, Fazio, F, Zito, F, Carpinelli, A, d'Amico, A, Rizzo, G, Moresco, R M, Paulesu, E, Franceschi, M, Lucignani, G

“…Functional imaging of the presynaptic dopaminergic activity using single-photon emission tomography (SPET) and iodine-123 labelled…”
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New perspectives on neurochemical effects of amantadine in the brain of parkinsonian patients: a PET - [11C]raclopride study by MORESCO, R. M, VOLONTE, M. A, MESSA, C, GOBBO, C, GALLI, L, CARPINELLI, A, RIZZO, G, PANZACCHI, A, FRANCESCHI, M, FAZIO, F

“…Amantadine, is a non competitive NMDA receptors antagonist that has been proved beneficial in Parkinson's disease. However its mechanism of action at…”
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Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model by Lo Dico, A., Martelli, C., Valtorta, S., Raccagni, I., Diceglie, C., Belloli, S., Gianelli, U., Vaira, V., Politi, L. S., Bosari, S., Lucignani, G., Moresco, R. M., Ottobrini, L.

“…Purpose Hypoxia-inducible factor 1α (HIF-1α) activity is one of the major players in hypoxia-mediated glioma progression and resistance to therapies, and…”
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Molecular imaging of individual behaviour by Moresco, R M, Fazio, F

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Labeling and Evaluation of N-[11C]Methylated Quinoline-2-carboxamides as Potential Radioligands for Visualization of Peripheral Benzodiazepine Receptors by Matarrese, Mario, Moresco, Rosa Maria, Cappelli, Andrea, Anzini, Maurizio, Vomero, Salvatore, Simonelli, Pasquale, Verza, Elisa, Magni, Fulvio, Sudati, Francesco, Soloviev, Dmitri, Todde, Sergio, Carpinelli, Assunta, Kienle, Marzia Galli, Fazio, Ferruccio

“…The novel quinoline-2-carboxamide derivatives N-[methyl-11C]-3-methyl-4-phenyl-N-(phenylmethyl)quinoline-2-carboxamide ([11C]4),…”
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SPET in psychopharmacolgy by Moresco, R M, Fazio, F

“…Positron emission tomography (PET) and single photon emission tomography (SPET) permit the in vivo assessment of human biological processes with methods…”
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Ethanol inhibits the binding of substance P to rat brain cortex NK1 receptors by SCARRONE, S, CAPPELLI, A, CUPELLO, A, MATARRESE, M, MORESCO, R. M, FAZIO, F

“…The binding of 125I-labeled substance P (SP) to rat brain cortex membranes has been studied under control conditions and in the presence of ethanol. The…”
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The use of spectral analysis to determine regional cerebral glucose utilization with positron emission tomography and [18F]fluorodeoxyglucose: theory, implementation, and optimization procedures by Turkheimer, F, Moresco, R M, Lucignani, G, Sokoloff, L, Fazio, F, Schmidt, K

“…A method for kinetic analysis of dynamic positron emission tomography (PET) data by linear programming that allows identification of the components of a…”
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Effects of Fluvoxamine Treatment on the in Vivo Binding of [F-18]FESP in Drug Naive Depressed Patients: A Pet Study by Moresco, R.M., Colombo, C., Fazio, F., Bonfanti, A., Lucignani, G., Messa, C., Gobbo, C., Galli, L., Del Sole, A., Lucca, A., Smeraldi, E.

“…Thisstudy investigates the effect of chronic treatment with Fluvoxamine, a potent and specific serotonin reuptake sites inhibitor (SSRI), on 5HT2 serotonin and…”
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The status of dopamine nerve terminals in Parkinson's disease and essential tremor: a PET study with the tracer [11-C]FE-CIT by Antonini, A, Moresco, R M, Gobbo, C, De Notaris, R, Panzacchi, A, Barone, P, Calzetti, S, Negrotti, A, Pezzoli, G, Fazio, F

“…Neuroimaging studies of the striatal dopamine transporter (DAT) are useful in the assessment of the dopaminergic system in Parkinson's disease (PD). We used…”
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Validation of an Engineered Cell Model for In Vitro and In Vivo HIF-1α Evaluation by Different Imaging Modalities by Lo Dico, A., Valtorta, S., Martelli, C., Belloli, S., Gianelli, U., Tosi, D., Bosari, S., Degrassi, A., Russo, M., Raccagni, I., Lucignani, G., Moresco, R. M., Ottobrini, L.

“…Purpose The aim of this study was to characterize a cell-based model for the molecular study of hypoxia-inducible factor (HIF)-1α activity, in the context of…”
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Validation and Performance Assessment of a Preclinical SiPM-Based SPECT/MRI Insert by Carminati, M., Valtorta, S., Belloli, S., Moresco, R. M., Savi, A., Iadanza, A., Falini, A., Politi, L. S., Cadioli, M., Hutton, B. F., Fiorini, C., Baratelli, F. M., Occhipinti, M., Erlandsson, K., Nagy, K., Nyitrai, Z., Czeller, M., Kuhne, A., Niendorf, T.

“…A preclinical insert for small animal simultaneous SPECT and MR imaging, in particular for imaging mouse brains, is presented. It consists of ten static…”
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Clinical PET imaging of tumour hypoxia in lung cancer by Incerti, E., Mapelli, P., Vuozzo, M., Fallanca, F., Monterisi, C., Bettinardi, V., Moresco, R. M., Gianolli, L., Picchio, M.

“…Purpose The aim of the present systematic review was to provide an overview on the different positron emission tomography (PET) hypoxia radiotracers in the…”
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Genetic and morphological diversity of Moenkhausia oligolepis (Characiformes: Characidae) populations in the tributaries of the Araguaia River, Brazil: implications for taxonomy and conservation by Domingos, T J, Moraes, L N, Moresco, R M, Margarido, V P, Venere, P C

“…Molecular genetic assessments that consider ecological information, in addition to endogamy levels, genetic diversity, and the genetic differentiation among…”
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