Search Results - "Morens, David"
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Emerging Pandemic Diseases: How We Got to COVID-19
Published in Cell (03-09-2020)“…Infectious diseases prevalent in humans and animals are caused by pathogens that once emerged from other animal hosts. In addition to these established…”
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Emerging infectious diseases: threats to human health and global stability
Published in PLoS pathogens (01-07-2013)“… HIV/AIDS, severe acute respiratory syndrome (SARS), and the most recent 2009 pandemic H1N1 influenza are only a few of many examples of emerging infectious…”
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Zika Virus in the Americas — Yet Another Arbovirus Threat
Published in The New England journal of medicine (18-02-2016)“…The explosive pandemic of Zika virus infection in South and Central America is the most recent of four unexpected arrivals of important arthropod-borne viral…”
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Escaping Pandora’s Box — Another Novel Coronavirus
Published in The New England journal of medicine (02-04-2020)“…With luck, public health control measures may be able to put the Covid-19 demons back in the jar. If they do not, we face a daunting challenge equal to, or…”
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Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness
Published in The Journal of infectious diseases (01-10-2008)“…Background. Despite the availability of published data on 4 pandemics that have occurred over the past 120 years, there is little modern information on the…”
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Universal Coronavirus Vaccines — An Urgent Need
Published in The New England journal of medicine (27-01-2022)“…We need a research approach that can characterize the global coronaviral universe, characterize the natural history and pathogenesis of coronaviruses in…”
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The 1918 influenza pandemic: 100 years of questions answered and unanswered
Published in Science translational medicine (24-07-2019)“…The 2018-2019 period marks the centennial of the "Spanish" influenza pandemic, which caused at least 50 million deaths worldwide. The unprecedented nature of…”
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Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses
Published in Cell host & microbe (11-01-2023)“…Viruses that replicate in the human respiratory mucosa without infecting systemically, including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many…”
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The Concept of Classical Herd Immunity May Not Apply to COVID-19
Published in The Journal of infectious diseases (24-08-2022)Get full text
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The Perpetual Challenge of Infectious Diseases
Published in The New England journal of medicine (02-02-2012)“…During the past 200 years, our understanding of infectious diseases has radically evolved from the identification of microbes, to defining their genetic…”
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Pandemic COVID-19 Joins History's Pandemic Legion
Published in mBio (29-05-2020)“…With great apprehension, the world is now watching the birth of a novel pandemic already causing tremendous suffering, death, and disruption of normal life…”
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The Pathogenesis of Ebola Virus Disease
Published in Annual review of pathology (24-01-2017)“…For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging across the vast equatorial belt of the African continent to cause…”
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Eastern Equine Encephalitis Virus — Another Emergent Arbovirus in the United States
Published in The New England journal of medicine (21-11-2019)“…In the summer and fall of 2019, nine U.S. states reported 36 human cases (14 of them fatal) of EEE, an arthropod-borne viral (arboviral) disease transmitted by…”
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The 1918 Influenza Pandemic and Its Legacy
Published in Cold Spring Harbor perspectives in medicine (01-10-2020)“…Just over a century ago in 1918-1919, the "Spanish" influenza pandemic appeared nearly simultaneously around the world and caused extraordinary…”
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The pathology of influenza virus infections
Published in Annual review of pathology (01-01-2008)“…Influenza viruses are significant human respiratory pathogens that cause both seasonal, endemic infections and periodic, unpredictable pandemics. The worst…”
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The Mother of All Pandemics Is 100 Years Old (and Going Strong)
Published in American journal of public health (1971) (01-11-2018)“…This year marks the 100th anniversary of the deadliest event in human history. In 1918-1919, pandemic influenza appeared nearly simultaneously around the globe…”
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A Centenary Tale of Two Pandemics: The 1918 Influenza Pandemic and COVID-19, Part I
Published in American journal of public health (1971) (01-06-2021)“…Separated by a century, the influenza pandemic of 1918 and the COVID-19 pandemic of 2019-2021 are among the most disastrous infectious disease emergences of…”
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New coronavirus outbreak: Framing questions for pandemic prevention
Published in Science translational medicine (11-03-2020)“…We need to understand and quantify the dominant variables that govern the SARS-CoV-2 outbreak, rather than relying exclusively on confirmed cases and their…”
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The Persistent Legacy of the 1918 Influenza Virus
Published in The New England journal of medicine (16-07-2009)“…Descendants of the H1N1 influenza A virus that caused the catastrophic and historic pandemic of 1918–1919 continue to contribute their genes to new viruses,…”
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Neuraminidase as an influenza vaccine antigen: a low hanging fruit, ready for picking to improve vaccine effectiveness
Published in Current opinion in immunology (01-08-2018)“…[Display omitted] •Neuraminidase (NA)-inhibiting antibodies are an independent correlate of vaccine efficacy.•Many NA-specific antibodies bind to conserved…”
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