Search Results - "Moreno Delgado, David"

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells by Moreno Delgado, David, Møller, Thor C, Ster, Jeanne, Giraldo, Jesús, Maurel, Damien, Rovira, Xavier, Scholler, Pauline, Zwier, Jurriaan M, Perroy, Julie, Durroux, Thierry, Trinquet, Eric, Prezeau, Laurent, Rondard, Philippe, Pin, Jean-Philippe

“…Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive…”
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Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland by González, Sergio, Moreno-Delgado, David, Moreno, Estefanía, Pérez-Capote, Kamil, Franco, Rafael, Mallol, Josefa, Cortés, Antoni, Casadó, Vicent, Lluís, Carme, Ortiz, Jordi, Ferré, Sergi, Canela, Enric, McCormick, Peter J

“…The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest…”
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Discovery of a small molecule modulator of the Kv1.1/Kvβ1 channel complex that reduces neuronal excitability and in vitro epileptiform activity by Niespodziany, Isabelle, Mullier, Brice, André, Véronique Marie, Ghisdal, Philippe, Jnoff, Eric, Moreno‐Delgado, David, Swinnen, Dominique, Sands, Zara, Wood, Martyn, Wolff, Christian

“…Summary Aims Kv1.1 (KCNA1) channels contribute to the control of neuronal excitability and have been associated with epilepsy. Kv1.1 channels can associate…”
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D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease by Sebastianutto, Irene, Goyet, Elise, Andreoli, Laura, Font-Ingles, Joan, Moreno-Delgado, David, Bouquier, Nathalie, Jahannault-Talignani, Céline, Moutin, Enora, Di Menna, Luisa, Maslava, Natallia, Pin, Jean-Philippe, Fagni, Laurent, Nicoletti, Ferdinando, Ango, Fabrice, Cenci, M Angela, Perroy, Julie

“…Dopamine receptor D1 modulates glutamatergic transmission in cortico-basal ganglia circuits and represents a major target of L-DOPA therapy in Parkinson's…”
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Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain by Callén, Lucía, Moreno, Estefanía, Barroso-Chinea, Pedro, Moreno-Delgado, David, Cortés, Antoni, Mallol, Josefa, Casadó, Vicent, Lanciego, José Luis, Franco, Rafael, Lluis, Carmen, Canela, Enric I., McCormick, Peter J.

“…Exploring the role of cannabinoid CB2 receptors in the brain, we present evidence of CB2 receptor molecular and functional interaction with cannabinoid CB1…”
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Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation by Scholler, Pauline, Nevoltris, Damien, de Bundel, Dimitri, Bossi, Simon, Moreno-Delgado, David, Rovira, Xavier, Møller, Thor C., El Moustaine, Driss, Mathieu, Michaël, Blanc, Emilie, McLean, Heather, Dupuis, Elodie, Mathis, Gérard, Trinquet, Eric, Daniel, Hervé, Valjent, Emmanuel, Baty, Daniel, Chames, Patrick, Rondard, Philippe, Pin, Jean-Philippe

“…Antibodies have enormous therapeutic and biotechnology potential. G protein-coupled receptors (GPCRs), the main targets in drug development, are of major…”
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Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease by Moreno-Delgado, David, Puigdellívol, Mar, Moreno, Estefanía, Rodríguez-Ruiz, Mar, Botta, Joaquín, Gasperini, Paola, Chiarlone, Anna, Howell, Lesley A, Scarselli, Marco, Casadó, Vicent, Cortés, Antoni, Ferré, Sergi, Guzmán, Manuel, Lluís, Carmen, Alberch, Jordi, Canela, Enric I, Ginés, Silvia, McCormick, Peter J

“…Early Huntington’s disease (HD) include over-activation of dopamine D1 receptors (D1R), producing an imbalance in dopaminergic neurotransmission and cell…”
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Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer by Liu, Junke, Zhang, Zongyong, Moreno-Delgado, David, Dalton, James Ar, Rovira, Xavier, Trapero, Ana, Goudet, Cyril, Llebaria, Amadeu, Giraldo, Jesús, Yuan, Qilin, Rondard, Philippe, Huang, Siluo, Liu, Jianfeng, Pin, Jean-Philippe

“…GPCRs play critical roles in cell communication. Although GPCRs can form heteromers, their role in signaling remains elusive. Here we used rat metabotropic…”
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Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine by Navarro, Gemma, Quiroz, César, Moreno-Delgado, David, Sierakowiak, Adam, McDowell, Kimberly, Moreno, Estefanía, Rea, William, Cai, Ning-Sheng, Aguinaga, David, Howell, Lesley A, Hausch, Felix, Cortés, Antonio, Mallol, Josefa, Casadó, Vicent, Lluís, Carme, Canela, Enric I, Ferré, Sergi, McCormick, Peter J

“…Release of the neuropeptides corticotropin-releasing factor (CRF) and orexin-A in the ventral tegmental area (VTA) play an important role in stress-induced…”
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Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway by Moreno-Delgado, David, Torrent, Anna, Gómez-Ramírez, Jordi, de Esch, Iwan, Blanco, Isaac, Ortiz, Jordi

“…We previously described that agonist-activated histamine H3 autoreceptors inhibit the stimulation of histamine synthesis mediated by calcium/calmodulin- and…”
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Class C G protein-coupled receptors: reviving old couples with new partners by Møller, Thor C., Moreno-Delgado, David, Pin, Jean-Philippe, Kniazeff, Julie

“…G protein-coupled receptors (GPCRs) are key players in cell communication and are encoded by the largest family in our genome. As such, GPCRs represent the…”
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H3 autoreceptors modulate histamine synthesis through calcium/calmodulin- and cAMP-dependent protein kinase pathways by Torrent, Anna, Moreno-Delgado, David, Gómez-Ramírez, Jordi, Rodríguez-Agudo, Daniel, Rodríguez-Caso, Carlos, Sánchez-Jiménez, Francisca, Blanco, Isaac, Ortiz, Jordí

“…H(3) autoreceptors provide feedback control of neurotransmitter synthesis in histaminergic neurons, but the transduction pathways involved are poorly…”
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Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer’s Disease by Rodríguez-Ruiz, Mar, Moreno, Estefanía, Moreno-Delgado, David, Navarro, Gemma, Mallol, Josefa, Cortés, Antonio, Lluís, Carme, Canela, Enric I., Casadó, Vicent, McCormick, Peter J., Franco, Rafael

“…Alzheimer’s disease (AD) is a neurodegenerative disorder causing progressive memory loss and cognitive dysfunction. Anti-AD strategies targeting cell receptors…”
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Opening the black box of energy throughputs in farm systems: A decomposition analysis between the energy returns to external inputs, internal biomass reuses and total inputs consumed (the Vallès County, Catalonia, c.1860 and 1999) by Tello, E., Galán, E., Sacristán, V., Cunfer, G., Guzmán, G.I., González de Molina, M., Krausmann, F., Gingrich, S., Padró, R., Marco, I., Moreno-Delgado, D.

“…We present an energy analysis of past and present farm systems aimed to contribute to their sustainability assessment. Looking at agroecosystems as a set of…”
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Spontaneous changes in brain striatal dopamine synthesis and storage dynamics ex vivo reveal end-product feedback-inhibition of tyrosine hydroxylase by González-Sepúlveda, Marta, Omar, Muhammad Yusof, Hamdon, Sally, Ma, Guofen, Rosell-Vilar, Santi, Raivio, Noora, Abass, Doaa, Martínez-Rivas, Anna, Vila, Miquel, Giraldo, Jesús, Carrascal, Montserrat, Abián, Joaquín, Gil, Carles, Sabriá, Josefa, Ortiz, Jordi, Moreno-Delgado, David

“…Synaptic events are important to define treatment strategies for brain disorders. In the present paper, freshly obtained rat brain striatal minces were…”
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HTS-compatible FRET-based conformational sensors clarify membrane receptor activation by Scholler, Pauline, Moreno-Delgado, David, Lecat-Guillet, Nathalie, Doumazane, Etienne, Monnier, Carine, Charrier-Savournin, Fabienne, Fabre, Ludovic, Chouvet, Cédric, Soldevila, Stéphanie, Lamarque, Laurent, Donsimoni, Geoffrey, Roux, Thomas, Zwier, Jurriaan M, Trinquet, Eric, Rondard, Philippe, Pin, Jean-Philippe

“…Optimizing the signal-to-noise ratio in time-resolved FRET through generation of agonist-responsive cell-surface receptor biosensors, including GABA B…”
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Heteroreceptor Complexes Formed by Dopamine D 1 , Histamine H 3 , and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer's Disease by Rodríguez-Ruiz, Mar, Moreno, Estefanía, Moreno-Delgado, David, Navarro, Gemma, Mallol, Josefa, Cortés, Antonio, Lluís, Carme, Canela, Enric I, Casadó, Vicent, McCormick, Peter J, Franco, Rafael

“…Alzheimer's disease (AD) is a neurodegenerative disorder causing progressive memory loss and cognitive dysfunction. Anti-AD strategies targeting cell receptors…”
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D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease by Sebastianutto, Irene, Goyet, Elise, Andreoli, Laura, Font-Ingles, Joan, Moreno-Delgado, David, Bouquier, Nathalie, Jahannault-Talignani, Céline, Moutin, Enora, Menna, Luisa Di, Maslava, Natallia, Pin, Jean-Philippe, Fagni, Laurent, Nicoletti, Ferdinando, Ango, Fabrice, Cenci, M Angela, Perroy, Julie

“…Dopamine receptor D1 modulates glutamatergic transmission in cortico-basal ganglia circuits and represents a major target of L-DOPA therapy in Parkinson's…”
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Modulation of dopamine D 1 receptors via histamine H 3 receptors is a novel therapeutic target for Huntington's disease by Moreno-Delgado, David, Puigdellívol, Mar, Moreno, Estefanía, Rodríguez-Ruiz, Mar, Botta, Joaquín, Gasperini, Paola, Chiarlone, Anna, Howell, Lesley A, Scarselli, Marco, Casadó, Vicent, Cortés, Antoni, Ferré, Sergi, Guzmán, Manuel, Lluís, Carmen, Alberch, Jordi, Canela, Enric I, Ginés, Silvia, McCormick, Peter J

“…Early Huntington's disease (HD) include over-activation of dopamine D receptors (D R), producing an imbalance in dopaminergic neurotransmission and cell death…”
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Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects by Moreno, Estefanía, Moreno-Delgado, David, Navarro, Gemma, Hoffmann, Hanne M, Fuentes, Silvia, Rosell-Vilar, Santi, Gasperini, Paola, Rodríguez-Ruiz, Mar, Medrano, Mireia, Mallol, Josefa, Cortés, Antoni, Casadó, Vicent, Lluís, Carme, Ferré, Sergi, Ortiz, Jordi, Canela, Enric, McCormick, Peter J

“…The general effects of cocaine are not well understood at the molecular level. What is known is that the dopamine D1 receptor plays an important role. Here we…”
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