Search Results - "Moreno, Yovany"
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Mining nematode protein secretomes to explain lifestyle and host specificity
Published in PLoS neglected tropical diseases (01-09-2021)“…Parasitic nematodes are highly successful pathogens, inflicting disease on humans, animals and plants. Despite great differences in their life cycles, host…”
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Stage- and gender-specific proteomic analysis of Brugia malayi excretory-secretory products
Published in PLoS neglected tropical diseases (01-10-2008)“…While we lack a complete understanding of the molecular mechanisms by which parasites establish and achieve protection from host immune responses, it is…”
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Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi
Published in Proceedings of the National Academy of Sciences - PNAS (16-11-2010)“…Ivermectin (IVM) is a broad-spectrum anthelmintic used in filariasis control programs. By binding to nematode glutamate-gated chloride channels (GluCls), IVM…”
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Australian Marine and Terrestrial Streptomyces -Derived Surugamides, and Synthetic Analogs, and Their Ability to Inhibit Dirofilaria immitis (Heartworm) Motility
Published in Marine drugs (09-07-2024)“…A bioassay-guided chemical investigation of a bacterium, sp. CMB-MRB032, isolated from sheep feces collected near Bathurst, Victoria, Australia, yielded the…”
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Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans
Published in Nature communications (2013)“…The macaque malaria parasite Plasmodium knowlesi has recently emerged as an important zoonosis in Southeast Asia. Infections are typically mild but can cause…”
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Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
Published in Nature communications (04-04-2016)“…Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell…”
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Macrocyclic lactone anthelmintics: spectrum of activity and mechanism of action
Published in Current pharmaceutical biotechnology (01-05-2012)“…Macrocyclic lactones (MLs), exemplified by the prototype of the class, ivermectin (IVM), are mainstays of programs for the control of nematode and arthropod…”
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Identification of anti-horn fly vaccine antigen candidates using a reverse vaccinology approach
Published in Parasites & vectors (03-09-2021)“…The horn fly, Haematobia irritans irritans, causes significant production losses to the cattle industry. Horn fly control relies on insecticides; however,…”
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A reverse vaccinology approach identified novel recombinant tick proteins with protective efficacy against Rhipicephalus microplus infestation
Published in Ticks and tick-borne diseases (01-11-2024)“…•Reverse vaccinology approach used to identity promising vaccine antigen candidates.•Using in silico rankings highest 200 ranked antigens manually…”
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Goondapyrones A-J: Polyketide α and γ Pyrone Anthelmintics from an Australian Soil-Derived Streptomyces sp
Published in Antibiotics (Basel) (18-10-2024)“…An investigation of ×19 soil samples collected under the auspices of the Australian citizen science initiative, Soils for Science, returned ×559 chemically…”
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Dirofilaria immitis JYD-34 isolate: whole genome analysis
Published in Parasites & vectors (09-11-2017)“…Macrocyclic lactone (ML) anthelmintics are used for chemoprophylaxis for heartworm infection in dogs and cats. Cases of dogs becoming infected with heartworms,…”
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Proteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information
Published in PLoS neglected tropical diseases (01-10-2011)“…The murine parasite Heligmosomoides polygyrus is a convenient experimental model to study immune responses and pathology associated with gastrointestinal…”
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Proteomic profiles of soluble proteins from the esophageal gland in female Meloidogyne incognita
Published in International journal for parasitology (01-12-2012)“…[Display omitted] ► A novel method was used to collect proteins secreted by adult female Meloidogyne incognita. ► The identification of the proteins in this…”
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First analysis of the secretome of the canine heartworm, Dirofilaria immitis
Published in Parasites & vectors (10-07-2012)“…BACKGROUND: The characterization of proteins released from filariae is an important step in addressing many of the needs in the diagnosis and treatment of…”
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Vulnerabilities in the internet of things
Published in Visión Electrónica (26-07-2019)“…The Internet of Things has allowed the connection of a countless number of devices, which has facilitated control and even decision-making by them, but at the…”
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When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions
Published in Trends in parasitology (01-06-2021)“…Helminth secretomes comprise many potential immunomodulators. The molecular and functional diversity of these entities and their importance at the…”
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Goondolinones A and B: Terpenyl-quinolin-4(1 H )-ones from an Australian Volcanic Crater Soil-Derived Actinomadura sp., with Selective Activity against Dirofilaria immitis (Heartworm)
Published in Journal of natural products (Washington, D.C.) (24-11-2024)“…A chemical investigation of the Australian pasture soil-derived Actinomadura sp. S4S-00245B09, supported by chemical, bioactivity and cultivation profiling,…”
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Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers
Published in American journal of hematology (01-01-2015)“…This paper demonstrates the enrichment of reticulocytes by centrifuging whole blood through aqueous multiphase systems (AMPSs)—immiscible phases of solutions…”
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Caracterización molecular de un banco de germoplasma del género Theobroma mediante la técnica RAPD
Published in Revista Colombiana de biotecnologia (01-07-2004)“…Mediante la utilización de marcadores RAPD (Random Amplified Polymorphic DNA), se analizaron 145 materiales (128 de T. grandiflorum y 17 de T. bicolor)…”
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