Search Results - "Moreno, Fernando Salvador"

Anticarcinogenic actions of tributyrin, a butyric acid prodrug by Heidor, Renato, Ortega, Juliana Festa, de Conti, Aline, Ong, Thomas Prates, Moreno, Fernando Salvador

“…Bioactive food compounds (BFCs) exhibit potential anticarcinogenic effects that deserve to be explored. Butyric acid (BA) is considered a promising BFC and has…”
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Associations between glutathione peroxidase-1 Pro198Leu polymorphism, selenium status, and DNA damage levels in obese women after consumption of Brazil nuts by Cominetti, Cristiane, Ph.D, de Bortoli, Maritsa Carla, Ph.D, Purgatto, Eduardo, Ph.D, Ong, Thomas Prates, Ph.D, Moreno, Fernando Salvador, Ph.D, Garrido, Arthur Belarmino, Ph.D, Cozzolino, Silvia Maria Franciscato, Ph.D

“…Abstract Objective Alterations in selenium (Se) status may result in suboptimal amounts of selenoproteins, which have been associated with increased oxidative…”
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Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase by Ong, Thomas Prates, Heidor, Renato, de Conti, Aline, Dagli, Maria Lúcia Zaidan, Moreno, Fernando Salvador

“…Chemopreventive activities of farnesol (FOH) and geraniol (GOH) were evaluated during the initial phases of hepatocarcinogenesis. Rats received during eight…”
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Chemoprevention of hepatocarcinogenesis with dietary isoprenic derivatives: cellular and molecular aspects by Ong, Thomas Prates, Cardozo, Monica Testoni, de Conti, Aline, Moreno, Fernando Salvador

“…Bioactive food components (BFACs) represent promising candidates for liver cancer chemoprevention. Among them, isoprenic derivatives (carotenoids, retinoids,…”
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Geranylgeraniol and β-ionone inhibit hepatic preneoplastic lesions, cell proliferation, total plasma cholesterol and DNA damage during the initial phases of hepatocarcinogenesis, but only the former inhibits NF-κB activation by de Moura Espíndola, Roseli, Mazzantini, Rogério Pietro, Ong, Thomas Prates, de Conti, Aline, Heidor, Renato, Moreno, Fernando Salvador

“…Chemopreventive activities of the isoprenoids geranylgeraniol (GGO) and β-ionone (BI) were evaluated during initial phases of hepatocarcinogenesis. Rats…”
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Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis by Romualdo, Guilherme Ribeiro, Rocha, Ariane Bartolomeu, Vinken, Mathieu, Cogliati, Bruno, Moreno, Fernando Salvador, Chaves, María Angel García, Barbisan, Luis Fernando

“…Recent meta-analyses indicate that coffee consumption reduces the risk for digestive tract (oral, esophageal, gastric and colorectal) and, especially, liver…”
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Butyrate-containing structured lipids act on HDAC4, HDAC6, DNA damage and telomerase activity during promotion of experimental hepatocarcinogenesis by Ortega, Juliana Festa, Heidor, Renato, Auriemo, Ana Paula, Marques Affonso, Juliana, Pereira D’ Amico, Thais, Herz, Corinna, de Conti, Aline, Ract, Juliana, Gioieli, Luiz Antônio, Purgatto, Eduardo, Lamy, Evelyn, P. Pogribny, Igor, Salvador Moreno, Fernando

“…Abstract Hepatocellular carcinoma (HCC) presents with a high treatment resistance and poor prognosis. Early diagnosis and preventive approaches such as…”
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Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models by Romualdo, Guilherme Ribeiro, Prata, Gabriel Bacil, da Silva, Tereza Cristina, Fernandes, Ana Angélica Henrique, Moreno, Fernando Salvador, Cogliati, Bruno, Barbisan, Luís Fernando

“…Hepatocellular carcinoma causes ~10% of all cancer-related deaths worldwide, usually emerging in a background of liver fibrosis/cirrhosis (70%-90% of cases)…”
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MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis by de Conti, Aline, Ortega, Juliana Festa, Tryndyak, Volodymyr, Dreval, Kostiantyn, Moreno, Fernando Salvador, Rusyn, Ivan, Beland, Frederick A, Pogribny, Igor P

“…Hepatocellular carcinoma (HCC) is the fastest-rising cause of cancer-related death in the United States. Recent epidemiological studies have identified…”
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Protective Effects of Dietary Capsaicin on the Initiation Step of a Two-Stage Hepatocarcinogenesis Rat Model by Sarmiento-Machado, Luis Manuel, Romualdo, Guilherme Ribeiro, Zapaterini, Joyce Regina, Tablas, Mariana Baptista, Fernandes, Ana Angélica Henrique, Moreno, Fernando Salvador, Barbisan, Luís Fernando

“…Capsaicin (CPS), an ingredient of Capsicum plants, has anti-inflammatory, antioxidant and antitumoral properties. The mechanisms of CPS on hepatocarcinogenesis…”
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Chemopreventive effects of β-ionone and geraniol during rat hepatocarcinogenesis promotion: distinct actions on cell proliferation, apoptosis, HMGCoA reductase, and RhoA by Cardozo, Mônica Testoni, de Conti, Aline, Ong, Thomas Prates, Scolastici, Clarissa, Purgatto, Eduardo, Horst, Maria Aderuza, Bassoli, Bruna Kempfer, Moreno, Fernando Salvador

“…Chemopreventive activities of the dietary isoprenoids β-ionone (βI) and geraniol (GOH) were evaluated during the promotion phase of hepatocarcinogenesis. Over…”
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Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: Efficacy of tributyrin, a butyric acid prodrug by Kuroiwa‐Trzmielina, Joice, de Conti, Aline, Scolastici, Clarissa, Pereira, Douglas, Horst, Maria Aderuza, Purgatto, Eduardo, Ong, Thomas Prates, Moreno, Fernando Salvador

“…Hepatocellular carcinoma (HCC) ranks in prevalence and mortality among top 10 cancers worldwide. Butyric acid (BA), a member of histone deacetylase inhibitors…”
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Squalene Does Not Exhibit a Chemopreventive Activity and Increases Plasma Cholesterol in a Wistar Rat Hepatocarcinogenesis Model by Scolastici, Clarissa, Ong, Thomas Prates, Moreno, Fernando Salvador

“…The eventual chemopreventive effect of squalene (SQ), a triterpene present in olive oil, was evaluated when administered to Wistar rats during a period…”
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Inhibitory Effects of Lutein and Lycopene on Placental Glutathione S-Transferase-Positive Preneoplastic Lesions and DNA Strand Breakage Induced in Wistar Rats by the Resistant Hepatocyte Model of Hepatocarcinogenesis by Toledo, Luciana Passos, Ong, Thomas Prates, Pinho, Ana Lucia Galvao, Jordao, Alceu, Vanucchi, Helio, Moreno, Fernando Salvador

“…Inhibitory effects of lutein (LUT) and lycopene (LYC) on hepatic preneoplastic lesions (PNLs) and DNA strand breakage induced in Wistar rats by the resistant…”
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Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarks by Romualdo, Guilherme Ribeiro, Heidor, Renato, Bacil, Gabriel Prata, Moreno, Fernando Salvador, Barbisan, Luís Fernando

“…Hepatocellular carcinoma (HCC), the main primary liver cancer, accounts for 5 % of all incident cases and 8.4 % of all cancer-related deaths worldwide. HCC…”
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Butyrate-containing structured lipids inhibit RAC1 and epithelial-to-mesenchymal transition markers: a chemopreventive mechanism against hepatocarcinogenesis by de Conti, Aline, Tryndyak, Volodymyr, Heidor, Renato, Jimenez, Leandro, Moreno, Fernando Salvador, Beland, Frederick A., Rusyn, Ivan, Pogribny, Igor P.

“…Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers. The rising incidence of HCC worldwide and its resistance to pharmacotherapy…”
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Ripe papaya pectins inhibit the proliferation of colon cancer spheroids and the formation of chemically induced aberrant crypts in rats colons by Donadio, Janaina L.S., Prado, Samira Bernardino Ramos do, Soares, Caroline Giacomelli, Tamarossi, Rodrigo Invernort, Heidor, Renato, Moreno, Fernando Salvador, Fabi, João Paulo

“…Pectins are a class of soluble polysaccharides that can have anticancer properties through several mechanisms. This study aimed to characterize the molecular…”
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Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents by Moreno, Fernando Salvador, Heidor, Renato, Pogribny, Igor P.

“…Hepatocellular carcinoma (HCC) is an aggressive and life-threatening disease often diagnosed at intermediate or advanced stages, which substantially limits…”
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The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation by Romualdo, Guilherme Ribeiro, Prata, Gabriel Bacil, da Silva, Tereza Cristina, Evangelista, Adriane Feijó, Reis, Rui Manuel, Vinken, Mathieu, Moreno, Fernando Salvador, Cogliati, Bruno, Barbisan, Luís Fernando

“…Aberrant microRNA expression implicates on hepatocellular carcinoma (HCC) development. Conversely, coffee consumption reduces by ~40% the risk for…”
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Erratum to: Butyrate-containing structured lipids act on HDAC4, HDAC6, DNA damage and telomerase activity during promotion of experimental hepatocarcinogenesis by Ortega, Juliana Festa, Heidor, Renato, Auriemo, Ana Paula, Affonso, Juliana Marques, D'Amico, Thais Pereira, Herz, Corinna, de Conti, Aline, Ract, Juliana, Gioieli, Luiz Antônio, Purgatto, Eduardo, Lamy, Evelyn, Pogribny, Igor P, Moreno, Fernando Salvador

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