Search Results - "Moreno, E."
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Cavities determine the pressure unfolding of proteins
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2012)“…It has been known for nearly 100 years that pressure unfolds proteins, yet the physical basis of this effect is not understood. Unfolding by pressure implies…”
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2
Molecular mechanisms involved in functional macroevolution of plant transcription factors
Published in The New phytologist (01-05-2021)“…Summary Transcription factors (TFs) are key components of the transcriptional regulation machinery. In plants, they accompanied the evolution from unicellular…”
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3
The pKa Cooperative: A collaborative effort to advance structure-based calculations of pKa values and electrostatic effects in proteins
Published in Proteins, structure, function, and bioinformatics (01-12-2011)“…The pKa Cooperative (http://www.pkacoop.org) was organized to advance development of accurate and useful computational methods for structure‐based calculation…”
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4
Arginine residues at internal positions in a protein are always charged
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2011)“…Many functionally essential ionizable groups are buried in the hydrophobic interior of proteins. A systematic study of Lys, Asp, and Glu residues at 25…”
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5
Affective neurolinguistics: towards a framework for reconciling language and emotion
Published in Language, cognition and neuroscience (03-09-2020)“…Standard neurocognitive models of language processing have tended to obviate the need for incorporating emotion processes, while affective neuroscience…”
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6
Arginine: Its pKa value revisited
Published in Protein science (01-05-2015)“…Using complementary approaches of potentiometry and NMR spectroscopy, we have determined that the equilibrium acid dissociation constant (pKa value) of the…”
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7
Large shifts in pKa values of lysine residues buried inside a protein
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…Internal ionizable groups in proteins are relatively rare but they are essential for catalysis and energy transduction. To examine molecular determinants of…”
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8
Impact of neurodegenerative diseases on human adult hippocampal neurogenesis
Published in Science (American Association for the Advancement of Science) (26-11-2021)“…Disrupted hippocampal performance underlies psychiatric comorbidities and cognitive impairments in patients with neurodegenerative disorders. To understand the…”
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9
Dupilumab: A Review of Present Indications and Off-Label Uses
Published in Journal of investigational allergology & clinical immunology (01-01-2022)“…Recent advances in our understanding of T2 inflammation have revealed more diseases in which T2 inflammation is involved. Dupilumab is a recently developed…”
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10
Protein Dielectric Constants Determined from NMR Chemical Shift Perturbations
Published in Journal of the American Chemical Society (13-11-2013)“…Understanding the connection between protein structure and function requires a quantitative understanding of electrostatic effects. Structure-based…”
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11
Entanglement of two qubits mediated by one-dimensional plasmonic waveguides
Published in Physical review letters (14-01-2011)“…We investigate qubit-qubit entanglement mediated by plasmons supported by one-dimensional waveguides. We explore both the situation of spontaneous formation of…”
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12
Charges in the hydrophobic interior of proteins
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2010)“…Charges are inherently incompatible with hydrophobic environments. Presumably for this reason, ionizable residues are usually excluded from the hydrophobic…”
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13
DDOTI Observations of Gravitational-Wave Sources Discovered in O3
Published in Monthly notices of the Royal Astronomical Society (01-10-2021)“…We present optical follow-up observations with the Deca-Degree Optical Transient Imager (DDOTI) telescope of gravitational-wave (GW) events detected during the…”
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14
Inclusion of insoluble fiber sources in mash or pellet diets for young broilers. 1. Effects on growth performance and water intake
Published in Poultry science (01-01-2016)“…The effects of feed form and the inclusion of insoluble fiber in the diet on growth performance and water intake were studied in female broilers from 0 to 21 d…”
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15
Three-float broad-band resonant line absorber with surge for wave energy conversion
Published in Renewable energy (01-06-2015)“…A line absorber consisting of three cylindrical floats is shown to have high crest capture widths for wave energy conversion across a broad band of…”
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16
Ultrafast terahertz response of multilayer graphene in the nonperturbative regime
Published in Physical review. B, Condensed matter and materials physics (27-01-2014)“…The nonlinear dynamics of electrons in multilayer epitaxial graphene is investigated by time-resolved terahertz (THz) spectroscopy in a regime where the…”
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17
Structural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a protein
Published in Proceedings of the National Academy of Sciences - PNAS (12-08-2014)“…An artificial charge pair buried in the hydrophobic core of staphyiococcal nuclease was engineered by making the V23E and L36K substitutions. Buried…”
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18
Conformational Reorganization Coupled to the Ionization of Internal Lys Residues in Proteins
Published in Biochemistry (Easton) (29-09-2015)“…Ionizable groups buried in the hydrophobic interior of proteins are essential for energy transduction and catalysis. Because the protein interior is usually…”
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19
Synthesis, structures and magnetic properties of [(η9-C9H9)Ln(η8-C8H8)] super sandwich complexes
Published in Nature communications (17-07-2019)“…Sandwich complexes are an indispensable part of organometallic chemistry, which is becoming increasingly important in the field of lanthanide-based single…”
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Structural, energetic, and dynamic responses of the native state ensemble of staphylococcal nuclease to cavity-creating mutations
Published in Proteins, structure, function, and bioinformatics (01-06-2013)“…The effects of cavity‐creating mutations on the structural flexibility, local and global stability, and dynamics of the folded state of staphylococcal nuclease…”
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