Search Results - "Moreno, Daniel Antunes"

Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia by ANTUNES MORENO, Daniel, SCRIDELI, Carlos Alberto, ABDALA CORTEZ, Maria Angélica, QUEIROZ, Rosane De Paula, TERCI VALERA, Elvis, DA SILVA SILVEIRA, Vanessa, YUNES, José Andres, BRANDALISE, Silvia Regina, GONZAGA TONE, Luiz

“…Altered expression of histone deacetylases (HDACs) is a common feature in several human malignancies and may represent an interesting target for cancer…”
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USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm by de Carvalho, Luiz Gustavo Almeida, Komoto, Tatiana Takahasi, Moreno, Daniel Antunes, Goes, João Vitor Caetano, de Oliveira, Roberta Taiane Germano, de Lima Melo, Mayara Magna, Roa, Mariela Estefany Gislene Vera, Gonçalves, Paola Gyuliane, Montefusco-Pereira, Carlos Victor, Pinheiro, Ronald Feitosa, Ribeiro Junior, Howard Lopes

“…The aim of this study was to evaluate the expression of , , , and genes in Myelodysplastic neoplasm (MDS) to identify possible targets of ubiquitination and…”
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Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets by Marques, Rui Ferreira, Moreno, Daniel Antunes, da Silva, Luciane, Leal, Leticia Ferro, de Paula, Flávia Escremim, Santana, Iara, Teixeira, Gustavo, Saggioro, Fabiano, Neder, Luciano, Junior, Carlos Almeida, Mançano, Bruna, Reis, Rui Manuel

“…Medulloblastoma is the most common and lethal pediatric malignant brain tumor. It comprises four main molecular subgroups: WNT-activated, SHH-activated, Group…”
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Role of Polygenic Risk Score in Cancer Precision Medicine of Non-European Populations: A Systematic Review by Junior, Howard Lopes Ribeiro, Novaes, Lázaro Antônio Campanha, Datorre, José Guilherme, Moreno, Daniel Antunes, Reis, Rui Manuel

“…The development of new screening methods and diagnostic tests for traits, common diseases, and cancer is linked to the advent of precision genomic medicine, in…”
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Cisplatin‑resistant germ cell tumor models: An exploration of the epithelial‑mesenchymal transition regulator SLUG by Cardoso, Ingridy Izabella Vieira, Rosa, Marcela Nunes, Moreno, Daniel Antunes, Tufi, Letícia Maria Barbosa, Ramos, Lorrayne Pereira, Pereira, Larissa Alessandra Bourdeth, Silva, Lenilson, Galvão, Janaina Mello Soares, Tosi, Isabela Cristiane, Lengert, André Van Helvoort, Da Cruz, Marcelo Cavalcanti, Teixeira, Silvia Aparecida, Reis, Rui Manuel, Lopes, Luiz Fernando, Pinto, Mariana Tomazini

“…Germ cell tumors (GCTs) constitute diverse neoplasms arising in the gonads or extragonadal locations. Testicular GCTs (TGCTs) are the predominant solid tumors…”
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High frequency of WNT-activated medulloblastomas with CTNNB1 wild type suggests a higher proportion of hereditary cases in a Latin-Iberian population by Moreno, Daniel Antunes, Bonatelli, Murilo, Antoniazzi, Augusto Perazzolo, de Paula, Flávia Escremim, Leal, Leticia Ferro, Garcia, Felipe Antônio de Oliveira, de Paula, André Escremim, Teixeira, Gustavo Ramos, Santana, Iara Viana Vidigal, Saggioro, Fabiano, Neder, Luciano, Valera, Elvis Terci, Scrideli, Carlos Alberto, Stavale, João, Malheiros, Suzana Maria Fleury, Lima, Matheus, Hajj, Glaucia Noeli Maroso, Garcia-Rivello, Hernan, Christiansen, Silvia, Nunes, Susana, Gil-da-Costa, Maria João, Pinheiro, Jorge, Martins, Flavia Delgado, Junior, Carlos Almeida, Mançano, Bruna Minniti, Reis, Rui Manuel

“…Purpose Medulloblastomas are the most common primary malignant brain tumors in children. They are divided into molecular subgroups: WNT-activated,…”
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Role of Sirtuins in the Pathobiology of Onco-Hematological Diseases: A PROSPERO-Registered Study and In Silico Analysis by Goes, João Vitor Caetano, Carvalho, Luiz Gustavo, de Oliveira, Roberta Taiane Germano, Melo, Mayara Magna de Lima, Novaes, Lázaro Antônio Campanha, Moreno, Daniel Antunes, Gonçalves, Paola Gyuliane, Montefusco-Pereira, Carlos Victor, Pinheiro, Ronald Feitosa, Ribeiro Junior, Howard Lopes

“…The sirtuins (SIRT) gene family (SIRT1 to SIRT7) contains the targets implicated in cellular and organismal aging. The role of SIRTs expression in the…”
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Reduced hydroxymethylation characterizes medulloblastoma while TET and IDH genes are differentially expressed within molecular subgroups by Bezerra Salomão, Karina, Cruzeiro, Gustavo Alencastro Veiga, Bonfim-Silva, Ricardo, Geron, Lenisa, Ramalho, Fernando, Pinto Saggioro, Fabiano, Serafini, Luciano Neder, Antunes Moreno, Daniel, de Paula Queiroz, Rosane Gomes, dos Santos Aguiar, Simone, Cardinalli, Izilda, Yunes, José Andres, Brandalise, Silvia Regina, Brassesco, Maria Sol, Scrideli, Carlos Alberto, Gonzaga Tone, Luiz

“…Introduction Medulloblastoma (MB) is an embryonal tumour that originates from genetic deregulation of cerebellar developmental pathways and is classified into…”
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Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients’ survival by Moreno, Daniel Antunes, da Silva, Luciane Sussuchi, Gomes, Isabella, Leal, Letícia Ferro, Berardinelli, Gustavo Noriz, Gonçalves, Gisele Melo, Pereira, Caio Augusto, Santana, Iara Viana Vidigal, Matsushita, Marcus de Medeiros, Bhat, Krishna, Lawler, Sean, Reis, Rui Manuel

“…Introduction: Glioblastoma (GBM), isocitrate dehydrogenase (IDH) wild-type (IDHwt), and grade 4 astrocytomas, IDH mutant (IDHmut), are the most common and…”
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Indisulam Reduces Viability and Regulates Apoptotic Gene Expression in Pediatric High-Grade Glioma Cells by Monção, Caio C D, Scrideli, Carlos A, Andrade, Augusto F, Viapiano, Mariano S, Carlotti, Carlos G, Moreno, Daniel Antunes, Baroni, Mirella, Tone, Luiz G, Teixeira, Silvia A

“…Pediatric high-grade glioma (pHGG) is one of the most aggressive brain tumors. Treatment includes surgery, radiotherapy, chemotherapy, or combination therapy…”
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Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells by Borges, Kleiton Silva, Castro-Gamero, Angel Maurício, Moreno, Daniel Antunes, da Silva Silveira, Vanessa, Brassesco, Maria Sol, de Paula Queiroz, Rosane Gomes, de Oliveira, Harley Francisco, Carlotti, Carlos Gilberto, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga

“…Background Glioblastoma remains one of the most devastating human malignancies, and despite therapeutic advances, there are no drugs that significantly improve…”
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Expression profile of apoptosis-related genes in childhood adrenocortical tumors: low level of expression of BCL2 and TNF genes suggests a poor prognosis by Lorea, Cecília Fernandes, Moreno, Daniel Antunes, Borges, Kleiton Silva, Martinelli, Carlos Eduardo, Antonini, Sonir Roberto Rauber, de Castro, Margaret, Tucci, Silvio, Neder, Luciano, Ramalho, Leandra Naira Zambelli, Cardinalli, Izilda, Seidinger, Ana Luiza, Mastellaro, Maria José, Yunes, José Andres, Brandalise, Silvia Regina, Tone, Luiz Gonzaga, Scrideli, Carlos Alberto

“…BackgroundImpaired apoptosis has been implicated in the development of childhood adrenocortical tumors (ACT), although the expression of apoptosis-related gene…”
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PD-L1 and MCL-1 markers and the relationship with prognostic characteristics of differentiated thyroid carcinoma by Zantut-Wittmann, Denise Engelbrecht, Barreto, Icleia Siqueira, Laus, Ana Carolina, Moreno, Daniel Antunes, Moma, Camila Aparecida, Maia, Frederico Fernandes Ribeiro, Assumpção, Lígia Vera Montali da, Reis, Rui Manuel

“…MCL-1 and PD-L1 proteins are related to carcinogenesis mechanisms in differentiated thyroid carcinoma(DTC). Tumor antigens stimulate the expression of PD-1 in…”
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Discrepancy in transcriptomic profiling between CD34 + stem cells and primary bone marrow cells in myelodysplastic neoplasm by Ribeiro Junior, Howard Lopes, Gonçalves, Paola Gyuliane, Moreno, Daniel Antunes, Goes, João Vitor Caetano, de Oliveira, Roberta Taiane Germano, Montefusco-Pereira, Carlos Victor, Komoto, Tatiana Takahasi, Pinheiro, Ronald Feitosa

“…Differentially expressed genes (DEGs) biomarkers can be used to help diagnose and monitor the disease, as well as to determine which treatments are most…”
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Survival Impact of Combined Biguanide and Temozolomide in Glioblastoma Preclinical Models: A Systematic Review and Meta-Analysis by Ferreira, Marcio Yuri, Thomaz de Assis, Eloísa Bittencurt, Batista, Savio, Palavani, Lucca B., Verly, Gabriel, Corrêa, Eduardo Mendes, Mitre, Lucas Pari, Sales de Oliveira, Jessica, Bertani, Raphael, Moreno, Daniel Antunes, Polverini, Allan Dias

“…Glioblastoma (GBM) is an aggressive tumor known for its poor prognosis. Despite extensive research into its molecular and clinical aspects, the current…”
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Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide by Gomes, Isabella, Moreno, Daniel Antunes, dos Reis, Mariana Bisarro, da Silva, Luciane Sussuchi, Leal, Letícia Ferro, Gonçalves, Gisele Melo, Pereira, Caio Augusto, Oliveira, Marco Antônio, de Medeiros Matsushita, Marcus, Reis, Rui Manuel

“…Introduction Glioblastoma (GBM) is the deadliest primary brain tumor. The standard treatment consists of surgery, radiotherapy, and temozolomide (TMZ). TMZ…”
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IUSP15-USP7/I Axis and IUBE2T/I Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm by de Carvalho, Luiz Gustavo Almeida, Komoto, Tatiana Takahasi, Moreno, Daniel Antunes, Goes, João Vitor Caetano, de Oliveira, Roberta Taiane Germano, de Lima Melo, Mayara Magna, Roa, Mariela Estefany Gislene Vera, Gonçalves, Paola Gyuliane, Montefusco-Pereira, Carlos Victor, Pinheiro, Ronald Feitosa, Ribeiro Junior, Howard Lopes

“…The aim of this study was to evaluate the expression of USP7, USP15, UBE2O, and UBE2T genes in Myelodysplastic neoplasm (MDS) to identify possible targets of…”
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Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP by Moreno, Daniel Antunes, Junior, Howard Lopes Ribeiro, Laranjeira, Angelo Brunelli Albertoni, Cruzeiro, Gustavo Alencastro Veiga, Borges, Kleiton Silva, Salomão, Karina Bezerra, Ramalho, Fernando Silva, Yunes, José Andres, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhães, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga

“…Patients diagnosed with acute lymphoblastic leukemia (ALL) bearing t(4;11)/MLL-AF4 have aggressive clinical features, poor prognosis and there is an urgent…”
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Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients by Viana-Pereira, Marta, Moreno, Daniel Antunes, Linhares, Paulo, Amorim, Júlia, Nabiço, Rui, Costa, Sandra, Vaz, Rui, Reis, Rui Manuel

“…Diffuse gliomas are the most common malignant primary brain tumors and remain incurable. A better knowledge of the tumor etiology is required. Specific single…”
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Somatic mutational profiling and clinical impact of driver genes in Latin-Iberian medulloblastomas: Towards precision medicine by Barateiro, Letícia Ganem Rillo Paz, de Oliveira Cavagna, Rodrigo, Dos Reis, Mariana Bisarro, de Paula, Flávia Escremim, Teixeira, Gustavo Ramos, Moreno, Daniel Antunes, Bonatelli, Murilo, Santana, Iara, Saggioro, Fabiano Pinto, Neder, Luciano, Stavale, João Norberto, Malheiros, Suzana Maria Fleury, Garcia-Rivello, Hernan, Christiansen, Silvia, Nunes, Susana, da Costa, Maria João Gil, Pinheiro, Jorge, Júnior, Carlos Almeida, Mançano, Bruna Minniti, Reis, Rui Manuel

“…Medulloblastoma (MB) is the most prevalent malignant brain tumor in children, known for its heterogeneity and treatment-associated toxicity, and there is a…”
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