Search Results - "Moreno, António J M"

Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis by Inácio, Ângela S, Domingues, Neuza S, Nunes, Alexandra, Martins, Patrícia T, Moreno, Maria J, Estronca, Luís M, Fernandes, Rui, Moreno, António J M, Borrego, Maria J, Gomes, João P, Vaz, Winchil L C, Vieira, Otília V

“…Broad-spectrum antimicrobial activity of quaternary ammonium surfactants (QAS) makes them attractive and cheap topical prophylactic options for sexually…”
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Mitochondria as the target for mildronate's protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria by Pupure, Jolanta, Fernandes, Maria A. S., Santos, Maria S., Moreno, António J. M., Kalvinsh, Ivars, Klusa, Vija, Oliveira, Catarina R.

“…Previously mildronate, an aza‐butyrobetaine derivative, was shown to be a cytoprotective drug, through its mechanism of action of inhibition of carnitine…”
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Mitochondrial Dysfunction Is the Focus of Quaternary Ammonium Surfactant Toxicity to Mammalian Epithelial Cells by INACIO, Angela S, COSTA, Gabriel N, DOMINGUES, Neuza S, SANTOS, Maria S, MORENO, António J. M, VAZ, Winchil L. C, VIEIRA, Otília V

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mechanism of inhibition of mitochondrial ATP synthase by 17β−Estradiol by Moreno, António J. M., Moreira, Paula I., Custódio, José B. A., Santos, Maria S.

“…17β-estradiol (E2) is considered to modulate the ATP synthase activity through direct binding to the oligomycin sensitive-conferring protein. We have…”
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Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat by Oliveira, Paulo J., Esteves, Telma C., Seiça, Raquel, Moreno, António J. M., Santos, Maria S.

“…Background Renal disease associated with diabetes mellitus is a major problem among diabetic patients. The role of mitochondria in the pathogenesis of diabetes…”
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Proton leak modulation in testicular mitochondria affects reactive oxygen species production and lipid peroxidation by Rodrigues, Ana Sofia, Lacerda, Beatriz, Moreno, António J. M., Ramalho-Santos, João

“…Mitochondrial proton leak can account for almost 20% of oxygen consumption and it is generally accepted that this process contributes to basal metabolism. In…”
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Sildenafil citrate concentrations not affecting oxidative phosphorylation depress H₂O₂ generation by rat heart mitochondria by Fernandes, Maria A. S, Marques, Ricardo J. F, Vicente, Joaquim A. F, Santos, Maria S, Monteiro, Pedro, Moreno, António J. M, Custódio, José B. A

“…Sildenafil citrate (Viagra) is a potent and specific inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), which…”
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Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions by Pereira, Gonçalo C, Branco, Ana F, Matos, Júlio A C, Pereira, Sandro L, Parke, Donna, Perkins, Edward L, Serafim, Teresa L, Sardão, Vilma A, Santos, Maria S, Moreno, Antonio J M, Holy, Jon, Oliveira, Paulo J

“…Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium] is an alkaloid present in plant extracts and has a…”
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Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanism by Oliveira, Paulo J, Esteves, Telma, Rolo, Anabela P, Palmeira, Carlos M, Moreno, António J M

“…It was previously shown that carvedilol, a beta-adrenergic receptor antagonist with antioxidant properties, was able to inhibit the mitochondrial permeability…”
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Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function by Custódio, José B.A, Santos, Maria S, Gonçalves, Dália I.R, Moreno, António J.M, Fernandes, Eduarda, Bastos, Maria L, Carvalho, Félix, Vicente, Joaquim A.F, Fernandes, Maria A.S

“…Abstract Ecstasy, which is used as a recreational drug, is a common street name for 3, 4-methylenedioxymethamphetamine (MDMA). Another drug of abuse chemically…”
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Use of a calcium-sensitive electrode for studies on mitochondrial calcium transport by Moreno, António J M, Vicente, Joaquim A

“…Ca(2+)-sensitive electrode as a practical approach is used to follow Ca(2+) changes in the medium and particularly useful to study mitochondrial Ca(2+) uptake…”
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Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells—Nuclear vs. mitochondrial effects by Serafim, Teresa L., Matos, Júlio A.C., Sardão, Vilma A., Pereira, Gonçalo C., Branco, Ana F., Pereira, Sandro L., Parke, Donna, Perkins, Edward L., Moreno, António J.M., Holy, Jon, Oliveira, Paulo J.

“…Sanguinarine (SANG) is an alkaloid recognized to have anti-proliferative activity against various human tumour cell lines. No data is available on the…”
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Toxicity of the herbicide linuron as assessed by bacterial and mitochondrial model systems by Santos, Sandra M.A., Videira, Romeu A., Fernandes, Maria A.S., Santos, Maria S., Moreno, António J.M., Vicente, Joaquim A.F., Jurado, Amália S.

“…•Linuron inhibited growth and respiratory activity of B. stearothermophilus.•Linuron perturbed respiration and oxidative phosphorylation of rat liver…”
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Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations – Relevance for carbaryl toxicity mechanisms by Moreno, Antonio J.M., Serafim, Teresa L., Oliveira, Paulo J., Madeira, Vitor M.C.

“…Although pesticides have been useful in agriculture pest control, there is a considerable risk for human health and damage to ecosystems. Carbaryl is a…”
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Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: relevance to hypoxia/reoxygenation injury by Oliveira, P J, Rolo, A P, Palmeira, C M, Moreno, A J

“…The cardioprotective properties of new pharmaceuticals such as carvedilol might be explained by enhanced mitochondrial protection. The aim of this work was to…”
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Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria by Rolo, A P, Oliveira, P J, Moreno, A J, Palmeira, C M

“…Several reports support the concept that bile acids may be cytotoxic during cholestatic disease process by causing mitochondrial dysfunction. Here we report…”
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Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systems by Pereira, Susana P., Fernandes, Maria A.S., Martins, João D., Santos, Maria S., Moreno, António J.M., Vicente, Joaquim A.F., Videira, Romeu A., Jurado, Amália S.

“…Metolachlor is one of the most intensively used chloroacetamide herbicides. However, its effects on the environment and on non-target animals and humans as…”
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Tetrandrine concentrations not affecting oxidative phosphorylation protect rat liver mitochondria from oxidative stress by Fernandes, Maria A S, Custódio, José B A, Santos, Maria S, Moreno, António J M, Vicente, Joaquim A F

“…The effects of tetrandrine (6,6', 7,12-tetramethoxy-2, 2'-dimethyl-berbaman) on the mitochondrial function were assessed on oxidative stress, mitochondrial…”
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Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability by Fernandes, Maria A. S., Santos, Maria S., Moreno, António J. M., Duburs, Gunars, Oliveira, Catarina R., Vicente, Joaquim A. F.

“…The interference of glibenclamide, an antidiabetic sulfonylurea, with mitochondrial bioenergetics was assessed on mitochondrial ion fluxes (H+, K+, and Cl−) by…”
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Cardiac Mitochondrial Calcium Loading Capacity Is Severely Affected after Chronic Cholestasis in Wistar Rats by Oliveira, Paulo J., Rolo, Anabela P., Seiça, Raquel, Santos, Maria S., Palmeira, Carlos M., Moreno, António J.M.

“…BackgroundCardiovascular changes correlated with some forms of hepatic disease are being reported in the literature.ObjectivesThe aim of this work was to…”
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