Search Results - "Morelli, Marco"

Cardiosomal microRNAs Are Essential in Post-Infarction Myofibroblast Phenoconversion by Morelli, Marco B, Shu, Jun, Sardu, Celestino, Matarese, Alessandro, Santulli, Gaetano

“…The inclusion of microRNAs (miRNAs) in extracellular microvesicles/exosomes (named cardiosomes when deriving from cardiomyocytes) allows their active…”
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Calcium supplements: Good for the bone, bad for the heart? A systematic updated appraisal by Morelli, Marco B., Santulli, Gaetano, Gambardella, Jessica

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Effects of Macromolecular Crowding on Genetic Networks by Morelli, Marco J., Allen, Rosalind J., Rein ten Wolde, Pieter

“…The intracellular environment is crowded with proteins, DNA, and other macromolecules. Under physiological conditions, macromolecular crowding can alter both…”
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Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis by Sabò, Arianna, Kress, Theresia R., Pelizzola, Mattia, de Pretis, Stefano, Gorski, Marcin M., Tesi, Alessandra, Morelli, Marco J., Bora, Pranami, Doni, Mirko, Verrecchia, Alessandro, Tonelli, Claudia, Fagà, Giovanni, Bianchi, Valerio, Ronchi, Alberto, Low, Diana, Müller, Heiko, Guccione, Ernesto, Campaner, Stefano, Amati, Bruno

“…Global transcriptional and epigenomic analyses in diverse cell types reveal that the primary action of Myc is to up- and downregulate transcription of distinct…”
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Vitamin C and Cardiovascular Disease: An Update by Morelli, Marco B, Gambardella, Jessica, Castellanos, Vanessa, Trimarco, Valentina, Santulli, Gaetano

“…The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we…”
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Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer by Walerych, Dawid, Lisek, Kamil, Sommaggio, Roberta, Piazza, Silvano, Ciani, Yari, Dalla, Emiliano, Rajkowska, Katarzyna, Gaweda-Walerych, Katarzyna, Ingallina, Eleonora, Tonelli, Claudia, Morelli, Marco J., Amato, Angela, Eterno, Vincenzo, Zambelli, Alberto, Rosato, Antonio, Amati, Bruno, Wiśniewski, Jacek R., Del Sal, Giannino

“…In cancer, the tumour suppressor gene TP53 undergoes frequent missense mutations that endow mutant p53 proteins with oncogenic properties. Until now, a…”
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Triamcinolone acetonide intralesional injection for the treatment of keloid scars: patient selection and perspectives by Morelli Coppola, Marco, Salzillo, Rosa, Segreto, Francesco, Persichetti, Paolo

“…Keloids are pathological scars presenting as nodular lesions that extend beyond the area of injury. They do not spontaneously regress, often continuing to grow…”
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The Role of Lipofilling After Breast Reconstruction: Evaluation of Outcomes and Patient Satisfaction with BREAST-Q by Cogliandro, Annalisa, Barone, Mauro, Tenna, Stefania, Morelli Coppola, Marco, Persichetti, Paolo

“…Introduction The aim of this study was to measure patient satisfaction using the BREAST-Q reconstruction module in patients selected for lipofilling procedures…”
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PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer by Fracassi, Cristina, Ugge', Martina, Abdelhalim, Mohamed, Zapparoli, Ettore, Simoni, Matilde, Magliulo, Daniela, Mazza, Davide, Lazarevic, Dejan, Morelli, Marco J, Collas, Philippe, Bernardi, Rosa

“…Abstract The promyelocytic leukemia (PML) protein organizes nuclear aggregates known as PML nuclear bodies (PML-NBs), where many transcription factors localize…”
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Using combined evidence from replicates to evaluate ChIP-seq peaks by Jalili, Vahid, Matteucci, Matteo, Masseroli, Marco, Morelli, Marco J

“…Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) detects genome-wide DNA-protein interactions and chromatin modifications, returning enriched…”
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From Angiosomal to Bi‐Angiosomal and Extra‐Angiosomal Pedicled Perforator Flaps: Optimizing the Use of Local Tissues in Abdominal Wall Reconstruction by Brunetti, Beniamino, Morelli Coppola, Marco, Petrucci, Valeria, Pazzaglia, Matteo, Camilloni, Chiara, Putti, Alessandra, Salzillo, Rosa, Tenna, Stefania, Cagli, Barbara, Persichetti, Paolo

“…ABSTRACT Introduction The use of free‐style and propeller perforator‐based flaps has been popularized for the reconstruction of moderate size defects in the…”
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Accurate and highly interpretable prediction of gene expression from histone modifications by Frasca, Fabrizio, Matteucci, Matteo, Leone, Michele, Morelli, Marco J, Masseroli, Marco

“…Histone Mark Modifications (HMs) are crucial actors in gene regulation, as they actively remodel chromatin to modulate transcriptional activity: aberrant…”
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The Lateral Thigh Perforator Propeller Flap: A Reliable Backup Plan for Locoregional Reconstruction in Case of Missing or Unreliable Anterolateral Thigh Perforators by Brunetti, Beniamino, Morelli Coppola, Marco, Tenna, Stefania, Persichetti, Paolo

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Machine learning approaches for prediction of bipolar disorder based on biological, clinical and neuropsychological markers: A systematic review and meta-analysis by Colombo, Federica, Calesella, Federico, Mazza, Mario Gennaro, Melloni, Elisa Maria Teresa, Morelli, Marco J., Scotti, Giulia Maria, Benedetti, Francesco, Bollettini, Irene, Vai, Benedetta

“…Applying machine learning (ML) to objective markers may overcome prognosis uncertainty due to the subjective nature of the diagnosis of bipolar disorder (BD)…”
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A Bayesian inference framework to reconstruct transmission trees using epidemiological and genetic data by Morelli, Marco J, Thébaud, Gaël, Chadœuf, Joël, King, Donald P, Haydon, Daniel T, Soubeyrand, Samuel

“…The accurate identification of the route of transmission taken by an infectious agent through a host population is critical to understanding its epidemiology…”
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Abdominal wall reconstruction with the free functional L-shaped latissimus dorsi flap: A case report by Brunetti, Beniamino, Salzillo, Rosa, Tenna, Stefania, Petrucci, Valeria, Morelli Coppola, Marco, Valeri, Sergio, Persichetti, Paolo

“…Extensive tridimensional defects of the abdominal wall are usually addressed with soft tissue flaps combined with meshes. In this scenario, the additional…”
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An early Myc‐dependent transcriptional program orchestrates cell growth during B‐cell activation by Tesi, Alessandra, de Pretis, Stefano, Furlan, Mattia, Filipuzzi, Marco, Morelli, Marco J, Andronache, Adrian, Doni, Mirko, Verrecchia, Alessandro, Pelizzola, Mattia, Amati, Bruno, Sabò, Arianna

“…Upon activation, lymphocytes exit quiescence and undergo substantial increases in cell size, accompanied by activation of energy‐producing and anabolic…”
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Using combined evidence from replicates to evaluate ChIP-seq peaks by Jalili, Vahid, Matteucci, Matteo, Masseroli, Marco, Morelli, Marco J

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Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation by de Pretis, Stefano, Kress, Theresia R, Morelli, Marco J, Sabò, Arianna, Locarno, Chiara, Verrecchia, Alessandro, Doni, Mirko, Campaner, Stefano, Amati, Bruno, Pelizzola, Mattia

“…Overexpression of the MYC transcription factor causes its widespread interaction with regulatory elements in the genome but leads to the up- and…”
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Alterations in glutamate, arginine, and energy metabolism characterize cerebrospinal fluid and plasma metabolome of persons with HIV-associated dementia by Mastrangelo, Andrea, Scotti, Giulia Maria, Manteiga, Jose Garcia, Gisslén, Magnus, Price, Richard W, Bestetti, Arabella, Turrini, Filippo, Caccia, Roberta, Gorelik, Leonid, Morelli, Marco J, Castagna, Antonella, Cinque, Paola

“…HIV-associated dementia (HAD) is the most severe clinical expression of HIV-mediated neuropathology, and the processes underlying its development remain poorly…”
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