Search Results - "Morelli, J"

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis by Sabò, Arianna, Kress, Theresia R., Pelizzola, Mattia, de Pretis, Stefano, Gorski, Marcin M., Tesi, Alessandra, Morelli, Marco J., Bora, Pranami, Doni, Mirko, Verrecchia, Alessandro, Tonelli, Claudia, Fagà, Giovanni, Bianchi, Valerio, Ronchi, Alberto, Low, Diana, Müller, Heiko, Guccione, Ernesto, Campaner, Stefano, Amati, Bruno

“…Global transcriptional and epigenomic analyses in diverse cell types reveal that the primary action of Myc is to up- and downregulate transcription of distinct…”
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Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer by Walerych, Dawid, Lisek, Kamil, Sommaggio, Roberta, Piazza, Silvano, Ciani, Yari, Dalla, Emiliano, Rajkowska, Katarzyna, Gaweda-Walerych, Katarzyna, Ingallina, Eleonora, Tonelli, Claudia, Morelli, Marco J., Amato, Angela, Eterno, Vincenzo, Zambelli, Alberto, Rosato, Antonio, Amati, Bruno, Wiśniewski, Jacek R., Del Sal, Giannino

“…In cancer, the tumour suppressor gene TP53 undergoes frequent missense mutations that endow mutant p53 proteins with oncogenic properties. Until now, a…”
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Effects of Macromolecular Crowding on Genetic Networks by Morelli, Marco J., Allen, Rosalind J., Rein ten Wolde, Pieter

“…The intracellular environment is crowded with proteins, DNA, and other macromolecules. Under physiological conditions, macromolecular crowding can alter both…”
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PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer by Fracassi, Cristina, Ugge', Martina, Abdelhalim, Mohamed, Zapparoli, Ettore, Simoni, Matilde, Magliulo, Daniela, Mazza, Davide, Lazarevic, Dejan, Morelli, Marco J, Collas, Philippe, Bernardi, Rosa

“…Abstract The promyelocytic leukemia (PML) protein organizes nuclear aggregates known as PML nuclear bodies (PML-NBs), where many transcription factors localize…”
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Accurate and highly interpretable prediction of gene expression from histone modifications by Frasca, Fabrizio, Matteucci, Matteo, Leone, Michele, Morelli, Marco J, Masseroli, Marco

“…Histone Mark Modifications (HMs) are crucial actors in gene regulation, as they actively remodel chromatin to modulate transcriptional activity: aberrant…”
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Interferon‐free therapy for genotype 1 hepatitis C in liver transplant recipients: Real‐world experience from the hepatitis C therapeutic registry and research network by Brown, Robert S., O'Leary, Jacqueline G., Reddy, K. Rajender, Kuo, Alexander, Morelli, Giuseppe J., Burton, James R., Stravitz, R. Todd, Durand, Christine, Bisceglie, Adrian M., Kwo, Paul, Frenette, Catherine T., Stewart, Thomas G., Nelson, David R., Fried, Michael W., Terrault, Norah A.

“…Recurrent infection with the hepatitis C virus (HCV) after liver transplantation (LT) is associated with decreased graft and patient survival. Achieving…”
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methylPipe and compEpiTools: a suite of R packages for the integrative analysis of epigenomics data by Kishore, Kamal, de Pretis, Stefano, Lister, Ryan, Morelli, Marco J, Bianchi, Valerio, Amati, Bruno, Ecker, Joseph R, Pelizzola, Mattia

“…Numerous methods are available to profile several epigenetic marks, providing data with different genome coverage and resolution. Large epigenomic datasets are…”
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Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors by Donato, E, Croci, O, Sabò, A, Muller, H, Morelli, M J, Pelizzola, M, Campaner, S

“…Inhibition of bromodomain and extraterminal motif (BET) proteins such as BRD4 bears great promise for cancer treatment and its efficacy has been frequently…”
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RNA sequencing of blood from sex- and age-matched discordant siblings supports immune and transcriptional dysregulation in autism spectrum disorder by Tomaiuolo, Pasquale, Piras, Ignazio Stefano, Sain, Simona Baghai, Picinelli, Chiara, Baccarin, Marco, Castronovo, Paola, Morelli, Marco J., Lazarevic, Dejan, Scattoni, Maria Luisa, Tonon, Giovanni, Persico, Antonio M.

“…Autism spectrum disorder (ASD) is a neurodevelopmental condition with onset in early childhood, still diagnosed only through clinical observation due to the…”
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INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments by de Pretis, Stefano, Kress, Theresia, Morelli, Marco J, Melloni, Giorgio E M, Riva, Laura, Amati, Bruno, Pelizzola, Mattia

“…Cellular mRNA levels originate from the combined action of multiple regulatory processes, which can be recapitulated by the rates of pre-mRNA synthesis,…”
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Refueling of field-reversed configuration core via axial plasmoids injection by Asai, T., Takahashi, T., Kobayashi, D., Seki, T., Takeuchi, Y., Mitarai, O., Morelli, J., Mizuguchi, N., Dettrick, S., Gota, H., Roche, T., Matsumoto, T., Binderbauer, M., Tajima, T., Inomoto, M., Takahashi, T.

“…Abstract This study successfully developed a refueling technique for a field-reversed configuration (FRC) via axial plasmoid injection and demonstrated it on…”
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T2 mapping in dermatomyositis/polymyositis and correlation with clinical parameters by Ran, J., Ji, S., Morelli, J.N., Wu, G., Li, X.

“…To explore the T2-mapping signal characteristics of the thigh muscles in patients with dermatomyositis/polymyositis (DM/PM) and to investigate the correlation…”
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A Bayesian inference framework to reconstruct transmission trees using epidemiological and genetic data by Morelli, Marco J, Thébaud, Gaël, Chadœuf, Joël, King, Donald P, Haydon, Daniel T, Soubeyrand, Samuel

“…The accurate identification of the route of transmission taken by an infectious agent through a host population is critical to understanding its epidemiology…”
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PML is a constitutive component of chromatin domains enriched in repetitive elements and duplicated gene clusters in cancer cells by Fracassi, Cristina, Simoni, Matilde, Uggè, Martina, Morelli, Marco J., Bernardi, Rosa

“…Heterochromatin is a pivotal element in the functional organization of genomes. In our study, we delve into the heterochromatin pattern of association by the…”
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Beyond the Consensus: Dissecting Within-Host Viral Population Diversity of Foot-and-Mouth Disease Virus by Using Next-Generation Genome Sequencing by WRIGHT, Caroline F, MORELLI, Marco J, THEBAUD, Gaël, KNOWLES, Nick J, HERZYK, Pawel, PATON, David J, HAYDON, Daniel T, KING, Donald P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemia by Magliulo, Daniela, Simoni, Matilde, Caserta, Carolina, Fracassi, Cristina, Belluschi, Serena, Giannetti, Kety, Pini, Raffaella, Zapparoli, Ettore, Beretta, Stefano, Uggè, Martina, Draghi, Eleonora, Rossari, Federico, Coltella, Nadia, Tresoldi, Cristina, Morelli, Marco J, Di Micco, Raffaella, Gentner, Bernhard, Vago, Luca, Bernardi, Rosa

“…One of the defining features of acute myeloid leukemia (AML) is an arrest of myeloid differentiation whose molecular determinants are still poorly defined…”
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Ex vivo detection of mesiobuccal canals in maxillary molars using CBCT at four different isotropic voxel dimensions by Bauman, R., Scarfe, W., Clark, S., Morelli, J., Scheetz, J., Farman, A.

“…Bauman R, Scarfe W, Clark S, Morelli J, Scheetz J, Farman A. Ex vivo detection of mesiobuccal canals in maxillary molars using CBCT at four different isotropic…”
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Differentiation of giant cell tumours of bone, primary aneurysmal bone cysts, and aneurysmal bone cysts secondary to giant cell tumour of bone: using whole-tumour CT texture analysis parameters as quantitative biomarkers by Wang, J.-Y., Sun, D., Liu, C.-Y., Hou, B.-W., Li, Y.-T., Hu, S., Zhang, Y., Morelli, J.N., Li, X.-M.

“…To determine whether computed tomography (CT) texture analysis parameters can be used as quantitative biomarkers to help differentiate giant cell tumour of…”
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3 Tesla proton MRI for the diagnosis of pneumonia/lung infiltrates in neutropenic patients with acute myeloid leukemia: Initial results in comparison to HRCT by Attenberger, U.I, Morelli, J.N, Henzler, T, Buchheidt, D, Fink, C, Schoenberg, S.O, Reichert, M

“…Abstract Purpose To evaluate the diagnostic accuracy of 3 Tesla proton MRI for the assessment of pneumonia/lung infiltrates in neutropenic patients with acute…”
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Metal artefact reduction in MRI at both 1.5 and 3.0 T using slice encoding for metal artefact correction and view angle tilting by Reichert, M, Ai, T, Morelli, J N, Nittka, M, Attenberger, U, Runge, V M

“…To compare metal artefact reduction in MRI at both 3.0 T and 1.5 T using different sequence strategies. Metal implants of stainless steel screw and plate…”
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