Search Results - "Morel, Carlos M"
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The Global Virome Project
Published in Science (American Association for the Advancement of Science) (23-02-2018)“…Expanded viral discovery can improve mitigation Outbreaks of novel and deadly viruses highlight global vulnerability to emerging diseases, with many having…”
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Significance of a neglected tropical disease: lessons from a paradigmatic case of 'success in translation'
Published in Memórias do Instituto Oswaldo Cruz (01-01-2022)“…In a previous publication, I stressed the fundamental importance of research for improving health using as an example the control of Chagas disease in the…”
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3
Hematological alterations associated with long COVID-19
Published in Frontiers in physiology (24-07-2023)“…Long COVID-19 is a condition characterized by persistent symptoms lasting beyond the acute phase of COVID-19. Long COVID-19 produces diverse symptomatology and…”
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Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein
Published in Cell (13-06-2019)“…Arthritogenic alphaviruses, such as Chikungunya virus (CHIKV), cause severe and debilitating rheumatic diseases worldwide, resulting in severe morbidity and…”
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The onchocerciasis chronicle: from the beginning to the end?
Published in Trends in parasitology (01-07-2012)“…The year 2012 marks the 25th anniversary of the donation of ivermectin to fight onchocerciasis and the projected date for elimination of transmission of the…”
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Genomic landscape of the emerging XDR Salmonella Typhi for mining druggable targets clpP, hisH, folP and gpmI and screening of novel TCM inhibitors, molecular docking and simulation analyses
Published in BMC microbiology (21-01-2023)“…Typhoid fever is transmitted by ingestion of polluted water, contaminated food, and stool of typhoid-infected individuals, mostly in developing countries with…”
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New Insights into Hemopexin-Binding to Hemin and Hemoglobin
Published in International journal of molecular sciences (30-03-2022)“…Hemopexin (Hx) is a plasma glycoprotein that scavenges heme (Fe(III) protoporphyrin IX). Hx has important implications in hemolytic disorders and hemorrhagic…”
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Drug Discovery for Paediatric Chagas Disease
Published in Mini reviews in medicinal chemistry (01-01-2018)“…Chagas disease is caused by the parasite Trypanosoma cruzi and is regularly found among particular people living in Central and South America. Paediatric…”
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Genetic Evidence and Host Immune Response in Persons Reinfected with SARS-CoV-2, Brazil
Published in Emerging infectious diseases (01-05-2021)“…The dynamics underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection remain poorly understood. We identified a small cluster of…”
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Enhanced Assessment of Cross-Reactive Antigenic Determinants within the Spike Protein
Published in International journal of molecular sciences (01-08-2024)“…Despite successful vaccination efforts, the emergence of new SARS-CoV-2 variants poses ongoing challenges to control COVID-19. Understanding humoral responses…”
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Performance assessment of a multi-epitope chimeric antigen for the serological diagnosis of acute Mayaro fever
Published in Scientific reports (28-07-2021)“…Mayaro virus (MAYV), which causes mayaro fever, is endemic to limited regions of South America that may expand due to the possible involvement of Aedes spp…”
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An Update on the Therapeutic Potential of Antimicrobial Peptides against Acinetobacter baumannii Infections
Published in Pharmaceuticals (Basel, Switzerland) (11-09-2023)“…The rise in antibiotic-resistant strains of clinically important pathogens is a major threat to global health. The World Health Organization (WHO) has…”
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Rapid Detection of Anti-SARS-CoV-2 Antibodies with a Screen-Printed Electrode Modified with a Spike Glycoprotein Epitope
Published in Biosensors (Basel) (26-04-2022)“…The coronavirus disease of 2019 (COVID-19) is caused by an infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was recognized in…”
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B-Cell Epitope Mapping of the Vibrio cholera Toxins A, B, and P and an ELISA Assay
Published in International journal of molecular sciences (28-12-2022)“…Oral immunization with the choleric toxin (CT) elicits a high level of protection against its enterotoxin activities and can control cholera in endemic…”
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A Multi-Epitope Protein for High-Performance Serodiagnosis of Chronic Chagas Disease in ELISA and Lateral Flow Platforms
Published in International journal of molecular sciences (11-09-2024)“…We developed a protein to rapidly and accurately diagnose Chagas disease, a life-threatening illness identified by the WHO as a critical worldwide public…”
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The Brazilian Dilemma: Increased Scientific Production and High Publication Costs during a Global Health Crisis and Major Economic Downturn
Published in mBio (28-06-2016)Get full text
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High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design
Published in Toxins (24-03-2023)“…Tetanus is an acute, fatal disease caused by exotoxins released from during infections. A protective humoral immune response can be induced by vaccinations…”
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Recent Advances in Synthetic Chemistry of Diabetic Research
Published in Mini reviews in medicinal chemistry (01-01-2015)“…Diseases started even before the existence of human beings. Therefore, when the civilization began, the biggest threats for human were diseases. Man has made…”
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Humoral Immune Response to SARS-CoV-2 Spike Protein Receptor-Binding Motif Linear Epitopes
Published in Vaccines (Basel) (01-04-2024)“…The worldwide spread of SARS-CoV-2 has led to a significant economic and social burden on a global scale. Even though the pandemic has concluded, apprehension…”
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Mapping IgA Epitope and Cross-Reactivity between Severe Acute Respiratory Syndrome-Associated Coronavirus 2 and DENV
Published in Vaccines (Basel) (24-11-2023)“…The newly introduced COVID-19 vaccines have reduced disease severity and hospitalizations. However, they do not significantly prevent infection or…”
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