Search Results - "Moreira, Thais G"

Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila by Liu, Shirong, Rezende, Rafael M., Moreira, Thais G., Tankou, Stephanie K., Cox, Laura M., Wu, Meng, Song, Anya, Dhang, Fyonn H., Wei, Zhiyun, Costamagna, Gianluca, Weiner, Howard L.

“…Fecal transfer from healthy donors is being explored as a microbiome modality. MicroRNAs (miRNAs) have been found to affect the microbiome. Multiple sclerosis…”
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Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19 by G Moreira, Thais, Gauthier, Christian D, Murphy, Liam, Lanser, Toby B, Paul, Anu, Matos, Kimble T F, Mangani, Davide, Izzy, Saef, Rezende, Rafael M, Healy, Brian C, Baecher-Allan, Clare M, Chitnis, Tanuja, Kuchroo, Vijay, Weiner, Howard L

“…T cells are present in early stages of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and play a major role in disease outcome and…”
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γδ T cells control humoral immune response by inducing T follicular helper cell differentiation by Rezende, Rafael M., Lanser, Amanda J., Rubino, Stephen, Kuhn, Chantal, Skillin, Nathaniel, Moreira, Thais G., Liu, Shirong, Gabriely, Galina, David, Bruna A., Menezes, Gustavo B., Weiner, Howard L.

“…γδ T cells have many known functions, including the regulation of antibody responses. However, how γδ T cells control humoral immunity remains elusive. Here we…”
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Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models by Wasén, Caroline, Beauchamp, Leah C., Vincentini, Julia, Li, Shuqi, LeServe, Danielle S., Gauthier, Christian, Lopes, Juliana R., Moreira, Thais G., Ekwudo, Millicent N., Yin, Zhuoran, da Silva, Patrick, Krishnan, Rajesh K., Butovsky, Oleg, Cox, Laura M., Weiner, Howard L.

“…The gut microbiota and microglia play critical roles in Alzheimer’s disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β…”
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PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis by Moreira, Thais G., Mangani, Davide, Cox, Laura M., Leibowitz, Jeffrey, Lobo, Eduardo. L. C., Oliveira, Mariana A., Gauthier, Christian D., Nakagaki, Brenda N., Willocq, Valerie, Song, Anya, Guo, Lydia, Lima, David C. A., Murugaiyan, Gopal, Butovsky, Oleg, Gabriely, Galina, Anderson, Ana C., Rezende, Rafael M., Faria, Ana Maria C., Weiner, Howard L.

“…The intestinal mucosa constitutes an environment of closely regulated immune cells. Dendritic cells (DC) interact with the gut microbiome and antigens and are…”
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Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study by Moreira, Thais G, Matos, Kimble T F, De Paula, Giovana S, Santana, Thais M M, Da Mata, Raquel G, Pansera, Fernando C, Cortina, Andre S, Spinola, Marcelle G, Baecher-Allan, Clare M, Keppeke, Gerson D, Jacob, Jules, Palejwala, Vaseem, Chen, Karen, Izzy, Saef, Healey, Brian C, Rezende, Rafael M, Dedivitis, Rogerio A, Shailubhai, Kunwar, Weiner, Howard L

“…Immune hyperactivity is an important contributing factor to the morbidity and mortality of COVID-19 infection. Nasal administration of anti-CD3 monoclonal…”
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Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects by Chitnis, Tanuja, Kaskow, Belinda J, Case, Junning, Hanus, Katherine, Li, Zhenhua, Varghese, Johnna F, Healy, Brian C, Gauthier, Christian, Saraceno, Taylor J, Saxena, Shrishti, Lokhande, Hrishikesh, Moreira, Thais G, Zurawski, Jonathan, Roditi, Rachel E, Bergmark, Regan W, Giovannoni, Federico, Torti, Maria F, Li, Zhaorong, Quintana, Francisco, Clementi, William A, Shailubhai, Kunwar, Weiner, Howard L, Baecher-Allan, Clare M

“…Parenteral anti-CD3 Mab (OKT3) has been used to treat transplant rejection and parental administration of a humanized anti-CD3 Mab (Teplizumab) showed positive…”
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Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance by Rezende, Rafael M, Cox, Laura M, Moreira, Thais G, Liu, Shirong, Boulenouar, Selma, Dhang, Fyonn, LeServe, Danielle S, Nakagaki, Brenda N, Lopes, Juliana R, Tatematsu, Bruna K, Lemos, Luisa, Mayrink, Julia, Lobo, Eduardo L C, Guo, Lydia, Oliveira, Marilia G, Kuhn, Chantal, Weiner, Howard L

“…Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition. Little is…”
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Corrigendum: Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study by Moreira, Thais G, Matos, Kimble T F, De Paula, Giovana S, Santana, Thais M M, Da Mata, Raquel G, Pansera, Fernando C, Cortina, Andre S, Spinola, Marcelle G, Baecher-Allan, Clare M, Keppeke, Gerson D, Jacob, Jules, Palejwala, Vaseem, Chen, Karen, Izzy, Saef, Healey, Brian C, Rezende, Rafael M, Dedivitis, Rogerio A, Shailubhai, Kunwar, Weiner, Howard L

“…[This corrects the article DOI: 10.3389/fimmu.2021.709861.]…”
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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells by Gabriely, Galina, Ma, Duanduan, Siddiqui, Shafiuddin, Sun, Linqing, Skillin, Nathaniel P., Abou-El-Hassan, Hadi, Moreira, Thais G., Donnelly, Dustin, da Cunha, Andre P., Fujiwara, Mai, Walton, Lena R., Patel, Amee, Krishnan, Rajesh, Levine, Stuart S., Healy, Brian C., Rezende, Rafael M., Murugaiyan, Gopal, Weiner, Howard L.

“…Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the…”
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γδ T Cell-Secreted XCL1 Mediates Anti-CD3-Induced Oral Tolerance by Rezende, Rafael M, Nakagaki, Brenda N, Moreira, Thais G, Lopes, Juliana R, Kuhn, Chantal, Tatematsu, Bruna K, Boulenouar, Selma, Maghzi, Amir-Hadi, Rubino, Stephen, Menezes, Gustavo B, Chitnis, Tanuja, Weiner, Howard L

“…Oral tolerance is defined as the specific suppression of cellular and/or humoral immune responses to an Ag by prior administration of the Ag through the oral…”
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Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice by Cox, Laura M., Tatematsu, Bruna K., Guo, Lydia, LeServe, Danielle S., Mayrink, Julia, Oliveira, Marilia G., Donnelly, Dustin, Fonseca, Roberta C., Lemos, Luisa, Lanser, Toby B., Rosa, Ana C., Lopes, Juliana R., Schwerdtfeger, Luke A., Ribeiro, Gabriela F.C., Lobo, Eduardo L.C., Moreira, Thais G., Oliveira, Andre G., Weiner, Howard L., Rezende, Rafael M.

“…•γδ T cells regulate the gut microbiota.•In the absence of γδ T cells, mice develop a microbial dysbiosis with the growth of microbes involved in the…”
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Dietary protein modulates intestinal dendritic cells to establish mucosal homeostasis by Moreira, Thais G., Cox, Laura M., Da Silva, Patrick, Mangani, Davide, De Oliveira, Marilia G., Escobar, Giulia, Lanser, Toby B., Murphy, Liam, Lobo, Eduardo.L.C., Milstein, Omer, Gauthier, Christian D., Clara Guimarāes, Ana, Schwerdtfeger, Luke, Ekwudo, Mellicient N., Wasén, Caroline, Liu, Shirong, Menezes, Gustavo B., Ferreira, Enio, Gabriely, Galina, Anderson, Ana C., Faria, Ana Maria C., Rezende, Rafael M., Weiner, Howard L.

“…Dietary proteins are taken up by intestinal dendritic cells (DCs), cleaved into peptides, loaded to major histocompatibility complexes, and presented to T…”
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Isolation and high‐dimensional phenotyping of gastrointestinal immune cells by David, Bruna A., Rubino, Stephen, Moreira, Thais G., Freitas‐Lopes, Maria Alice, Araújo, Alan M., Paul, Nicole E., Rezende, Rafael M., Menezes, Gustavo B.

“…Summary The gastrointestinal immune system plays a pivotal role in the host relationship with food antigens, the homeostatic microbiome and enteric pathogens…”
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Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo by Moreira, Thais G., Zhang, Liang, Shaulov, Lihi, Harel, Amnon, Kuss, Sharon K., Williams, Jessica, Shelton, John, Somatilaka, Bandarigoda, Seemann, Joachim, Yang, Jue, Sakthivel, Ramanavelan, Nussenzveig, Daniel R., Faria, Ana M. C., Fontoura, Beatriz M. A.

“…The Sec13 protein functions in various intracellular compartments including the nuclear pore complex, COPII-coated vesicles and inside the nucleus as a…”
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A defective TLR4 signaling for IFN-β expression is responsible for the innately lower ability of BALB/c macrophages to produce NO in response to LPS as compared to C57BL/6 by Oliveira, Luciana S, de Queiroz, Nina M G P, Veloso, Laura V S, Moreira, Thaís G, Oliveira, Fernanda S, Carneiro, Matheus B H, Faria, Ana M, Vieira, Leda Q, Oliveira, Sérgio C, Horta, Maria F

“…C57BL/6 mice macrophages innately produce higher levels of NO than BALB/c cells when stimulated with LPS. Here, we investigated the molecular events that…”
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Modulating CNS neuroinflammation in animal models of intracerebral hemorrhage by nasal anti-CD3 (S4.010) by Izzy, Saef, Yahya, Taha, Cao, Tian, Waed, Mokalad, Moreira, Thais G., Rezende, Rafael M., Weiner, Howard

“…Abstract only…”
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A Defective TLR4 Signaling for IFN-[beta] Expression Is Responsible for the Innately Lower Ability of BALB/c Macrophages to Produce NO in Response to LPS as Compared to C57BL/6 by Oliveira, Luciana S, de Queiroz, Nina M. G. P, Veloso, Laura V. S, Moreira, Thaís G, Oliveira, Fernanda S, Carneiro, Matheus B. H, Faria, Ana M, Vieira, Leda Q, Oliveira, Sérgio C, Horta, Maria F

“…C57BL/6 mice macrophages innately produce higher levels of NO than BALB/c cells when stimulated with LPS. Here, we investigated the molecular events that…”
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