Search Results - "Moreira, Douglas de Souza"

Mannosyltransferase (GPI-14) overexpression protects promastigote and amastigote forms of Leishmania braziliensis against trivalent antimony by Ribeiro, Christiana Vargas, Rocha, Bruna Fonte Boa, Moreira, Douglas de Souza, Peruhype-Magalhães, Vanessa, Murta, Silvane Maria Fonseca

“…Glycosylphosphatidylinositol is a surface molecule important for host-parasite interactions. Mannosyltransferase (GPI-14) is an essential enzyme for adding…”
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Ascorbate peroxidase overexpression protects Leishmania braziliensis against trivalent antimony effects by Moreira, Douglas de Souza, Xavier, Mariana Vieira, Murta, Silvane Maria Fonseca

“…Ascorbate peroxidase (APX) is a redox enzyme of the trypanothione pathway that converts hydrogen peroxide (H2O2) into water molecules. In the present study,…”
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Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology by Moreira, Douglas de Souza, Pescher, Pascale, Laurent, Christine, Lenormand, Pascal, Späth, Gerald F., Murta, Silvane M. F.

“…Protein phosphorylation is one of the most studied post‐translational modifications that is involved in different cellular events in Leishmania. In this study,…”
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Molecular characterization and functional analysis of pteridine reductase in wild-type and antimony-resistant Leishmania lines by de Souza Moreira, Douglas, Ferreira, Rafael Fernandes, Murta, Silvane M.F.

“…Pteridine reductase (PTR1) is an NADPH-dependent reductase that participates in the salvage of pteridines, which are essential to maintain growth of…”
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Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations by Moreira, Douglas de Souza, Duarte, Ana Paula, Pais, Fabiano Sviatopolk Mirsky, Silva-Pereira, Rosiane Aparecida da, Romanha, Alvaro José, Schenkman, Sergio, Murta, Silvane Maria Fonseca

“…Eukaryotic initiation factor 5A (eIF5A) is a conserved protein with an essential role in translation elongation. Using one and two-dimensional western…”
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Mapping Alterations Induced by Long-Term Axenic Cultivation of Leishmania amazonensis Promastigotes With a Multiplatform Metabolomic Fingerprint Approach by Crepaldi, Frederico, de Toledo, Juliano Simões, do Carmo, Anderson Oliveira, Ferreira Marques Machado, Leopoldo, de Brito, Daniela Diniz Viana, Serufo, Angela Vieira, Almeida, Ana Paula Martins, de Oliveira, Leandro Gonzaga, Ricotta, Tiago Queiroga Nery, Moreira, Douglas de Souza, Murta, Silvane Maria Fonseca, Diniz, Ariane Barros, Menezes, Gustavo Batista, López-Gonzálvez, Ángeles, Barbas, Coral, Fernandes, Ana Paula

“…Leishmaniases are widespread neglected diseases with an incidence of 1.6 million new cases and 40 thousand deaths per year. parasites may show distinct,…”
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Ascorbate peroxidase modulation confirms key role in Leishmania infantum oxidative defence by Santos, Isabella Fernandes Martins, Moreira, Douglas de Souza, Costa, Karla Ferreira, Ribeiro, Juliana Martins, Murta, Silvane Maria Fonseca, Santi, Ana Maria Murta

“…Abstract Background Ascorbate peroxidase (APX) has emerged as a promising target for chemotherapy because of its absence in humans and crucial role in the…”
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