Search Results - "Moreci, Rebecca S"

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions by Menk, Ashley V., Scharping, Nicole E., Moreci, Rebecca S., Zeng, Xue, Guy, Cliff, Salvatore, Sonia, Bae, Heekyong, Xie, Jianxin, Young, Howard A., Wendell, Stacy Gelhaus, Delgoffe, Greg M.

“…To fulfill bioenergetic demands of activation, T cells perform aerobic glycolysis, a process common to highly proliferative cells in which glucose is fermented…”
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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction by Scharping, Nicole E., Menk, Ashley V., Moreci, Rebecca S., Whetstone, Ryan D., Dadey, Rebekah E., Watkins, Simon C., Ferris, Robert L., Delgoffe, Greg M.

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Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination by Anamthathmakula, Prashanth, Miryala, Chandra Suma Johnson, Moreci, Rebecca S., Kyathanahalli, Chandrashekara, Hassan, Sonia S., Condon, Jennifer C., Jeyasuria, Pancharatnam

“…The elevated level of Steroidogenic Factor 1 ( Nr5a1, Sf-1 ) expression in the male gonadal development pathway, post sex determination, implies a vital role…”
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Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7–dependent by Kyathanahalli, Chandrashekara, Organ, Kenna, Moreci, Rebecca S., Anamthathmakula, Prashanth, Hassan, Sonia S., Caritis, Steve N., Jeyasuria, Pancharatnam, Condon, Jennifer C.

“…We previously identified myometrial caspase-3 (CASP3) as a potential regulator of uterine quiescence. We also determined that during pregnancy, the functional…”
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Restoration of spermatogenesis and male fertility using an androgen receptor transgene by Walker, William H, Easton, Evan, Moreci, Rebecca S, Toocheck, Corey, Anamthathmakula, Prashanth, Jeyasuria, Pancharatnam

“…Androgens signal through the androgen receptor (AR) to regulate male secondary sexual characteristics, reproductive tract development, prostate function, sperm…”
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Epidermal structure and differentiation by Moreci, Rebecca S., Lechler, Terry

“…In this Primer, Moreci and Lechler follow the lifetime of an epidermal cell from its birth to its ultimate death, and detail how this journey is necessary for…”
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KIF18B is a cell type-specific regulator of spindle orientation in the epidermis by Moreci, Rebecca S, Lechler, Terry

“…Proper spindle orientation is required for asymmetric cell division and the establishment of complex tissue architecture. In the developing epidermis, spindle…”
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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction by Scharping, Nicole E., Menk, Ashley V., Moreci, Rebecca S., Whetstone, Ryan D., Dadey, Rebekah E., Watkins, Simon C., Ferris, Robert L., Delgoffe, Greg M.

“…Although tumor-specific T cells recognize cancer cells, they are often rendered dysfunctional due to an immunosuppressive microenvironment. Here we showed that…”
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Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut by Bara, Anne M, Chen, Lei, Ma, Celina, Underwood, Julie, Moreci, Rebecca S, Sumigray, Kaelyn, Sun, Tongyu, Diao, Yarui, Verzi, Michael, Lechler, Terry

“…There are fundamental differences in how neonatal and adult intestines absorb nutrients. In adults, macromolecules are broken down into simpler molecular…”
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Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1 by Natarajan, Karthika, Xie, Yi, Nakanishi, Takeo, Moreci, Rebecca S, Jeyasuria, Pancharatnam, Hussain, Arif, Ross, Douglas D

“…Gene expression in different tissues is often controlled by alternative promoters that result in the synthesis of mRNA with unique - usually untranslated -…”
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Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1 by Xie, Yi, Natarajan, Karthika, Bauer, Kenneth S., Nakanishi, Takeo, Beck, William T., Moreci, Rebecca S., Jeyasuria, Pancharatnam, Hussain, Arif, Ross, Douglas D.

“…Alternative promoter usage is typically associated with mRNAs with differing first exons that contain or consist entirely of a 5′ untranslated region. The…”
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Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1 by Natarajan, Karthika, Xie, Yi, Nakanishi, Takeo, Moreci, Rebecca S., Jeyasuria, Pancharatnam, Hussain, Arif, Ross, Douglas D.

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Metabolic insufficiency underlies intratumoral cytotoxic T cell dysfunction by Gupta, Tushar, Scharping, Nicole E, Moreci, Rebecca S, Delgoffe, Greg M

“…T cells have the remarkable ability to recognize and remove abnormal cells with precision, a feature that is very desirable for the treatment of cancer…”
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Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene: e0120783 by Walker, William H, Easton, Evan, Moreci, Rebecca S, Toocheck, Corey, Anamthathmakula, Prashanth, Jeyasuria, Pancharatnam

“…Androgens signal through the androgen receptor (AR) to regulate male secondary sexual characteristics, reproductive tract development, prostate function, sperm…”
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Spindle Orientation Coordinates Cell Fate Decisions during Epidermal Morphogenesis by Moreci, Mary Rebecca S

“…Asymmetric cell divisions (ACDs) drive cell fate specification and the formation of complex tissue architecture. This often requires orienting the mitotic…”
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