Search Results - "Morecchiato, Fabio"
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Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae
Published in PLoS pathogens (01-07-2022)“…Mutations in outer membrane porins act in synergy with carbapenemase enzymes to increase carbapenem resistance in the important nosocomial pathogen, Klebsiella…”
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Amelioration of Serum Aβ Levels and Cognitive Impairment in APPPS1 Transgenic Mice Following Symbiotic Administration
Published in Nutrients (01-08-2024)“…Alzheimer's disease (AD) is a neurodegenerative process responsible for almost 70% of all cases of dementia. The clinical signs consist in progressive and…”
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Evaluation of extraction-free RT-PCR methods for faster and cheaper detection of SARS-CoV-2 using two commercial systems
Published in International journal of infectious diseases (01-11-2021)“…•Extraction-free methods allow faster and cheaper SARS-CoV-2 detection•Extraction-free methods showed good sensitivity with samples with high viral…”
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Validation of Two Commercial Multiplex Real-Time PCR Assays for Detection of SARS-CoV-2 in Stool Donors for Fecal Microbiota Transplantation
Published in Microorganisms (Basel) (26-01-2022)“…Recurrent infection by has recently been treated by fecal microbiota transplantation (FMT). As viable SARS-CoV-2 was recovered from stool of asymptomatic…”
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Detection of SARS-CoV-2 N protein allelic variants by rapid high-throughput CLEIA antigen assay
Published in Journal of clinical virology (01-09-2021)Get full text
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Multicenter study on the prevalence of colonization due to carbapenem-resistant Enterobacterales strains before and during the first year of COVID-19, Italy 2018-2020
Published in Frontiers in public health (2023)“…Among multidrug-resistant (MDR) bacteria able to threaten human health, carbapenem-resistant (CRE) have become a major public health threat globally. National…”
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In Vitro Alteration by Dentine and Protein of the Antimicrobial Activity of Two Endodontic Irrigants: HybenX® and Sodium Hypochlorite
Published in Antibiotics (Basel) (01-11-2020)“…Irrigant solutions commonly used for the treatment of endodontic infections can be inhibited by both organic and inorganic substances. The aim of this study…”
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Evaluation of STANDARD™ M10 SARS-CoV-2 from bronchoalveolar lavage samples
Published in Diagnostic microbiology and infectious disease (01-11-2024)“…•SARS-CoV-2 RNA is detectable also from lower respiratory tract specimen.•Rapid detection of SARS-CoV-2 is essential for critical patients or organ…”
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Evaluation of Quantamatrix dRASTTM system for rapid antimicrobial susceptibility testing of bacterial isolates from positive blood cultures, in comparison with commercial Micronaut broth microdilution system
Published in Diagnostic microbiology and infectious disease (01-09-2024)“…•Rapid antimicrobial susceptibility testing is relevant for sepsis management.•Quantamatrix dRASTTM can provide data for both Gram-negatives and…”
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Evaluation of Revogene® Carba C assay for the rapid detection of carbapenemase genes in gram-negative pathogens
Published in Diagnostic microbiology and infectious disease (01-03-2022)“…•Rapid carbapenemases characterization with a new RT-PCR commercial method.•Excellent sensitivity and specificity of Revogene Carba C assay vs reference…”
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Evaluation of different molecular systems for detection and quantification of SARS-CoV-2 RNA from wastewater samples
Published in Journal of virological methods (01-07-2024)“…Wastewater-based epidemiology has proved to be a suitable approach for tracking the spread of epidemic agents including SARS-CoV-2 RNA. Different protocols…”
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Verifying the feasibility of wastewater-based epidemiological monitoring for the small catchment and sewage networks with significant pretreatment
Published in Journal of water and health (01-08-2024)“…Wastewater-based epidemiology (WBE) has emerged as a valuable tool for COVID-19 monitoring, especially as the frequency of clinical testing diminishes. Beyond…”
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Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
Published in Diagnostic microbiology and infectious disease (01-10-2021)“…•SARS-CoV-2 antigens test could be interesting alternatives to RT-PCR•LFIA exhibited reduced sensitivity and high specificity•CLEIA showed higher sensitivity…”
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Laboratory data and broncho-alveolar lavage on Covid-19 patients with no intensive care unit admission: Correlation with chest CT features and clinical outcomes
Published in Medicine (Baltimore) (19-07-2024)“…Broncho-alveolar lavage (BAL) is indicated in cases of uncertain diagnosis but high suspicion of Sars-Cov-2 infection allowing to collect material for…”
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Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure
Published in Proceedings of the National Academy of Sciences - PNAS (20-09-2022)“…Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella pneumoniae , modifications in the porin OmpK36 are implicated in…”
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Evaluation of Quantamatrix dRAST TM system for rapid antimicrobial susceptibility testing of bacterial isolates from positive blood cultures, in comparison with commercial Micronaut broth microdilution system
Published in Diagnostic microbiology and infectious disease (01-09-2024)“…Antimicrobial susceptibility testing (AST) from blood culture (BC) may take several days, limiting the eventual impact on antimicrobial stewardship. Hence,…”
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Isothermal microcalorimetry vs checkerboard assay to evaluate in-vitro synergism of meropenem–amikacin and meropenem–colistin combinations against multi-drug-resistant Gram-negative pathogens
Published in International journal of antimicrobial agents (01-10-2022)“…OBJECTIVESTo evaluate the activity of meropenem-amikacin and meropenem-colistin combinations with checkerboard broth microdilution (CKBM) compared with…”
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