Search Results - "More, Piyush"

Nanoparticle-Mediated Mitochondrial Damage Induces Apoptosis in Cancer by Mallick, Abhik, More, Piyush, Syed, Muhammed Muazzam Kamil, Basu, Sudipta

“…Detouring of conventional DNA damaging anticancer drugs into mitochondria to damage mitochondrial DNA is evolving as a promising strategy in chemotherapy…”
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Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase by Ghosh, Sougata, More, Piyush, Derle, Abhishek, Patil, Ajay B, Markad, Pramod, Asok, Adersh, Kumbhar, Navanath, Shaikh, Mahemud L, Ramanamurthy, Boppana, Shinde, Vaishali S, Dhavale, Dilip D, Chopade, Balu A

“…Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to…”
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Transcriptional Response to Standard AML Drugs Identifies Synergistic Combinations by More, Piyush, Ngaffo, Joëlle Aurelie Mekontso, Goedtel-Armbrust, Ute, Hähnel, Patricia S, Hartwig, Udo F, Kindler, Thomas, Wojnowski, Leszek

“…Unlike genomic alterations, gene expression profiles have not been widely used to refine cancer therapies. We analyzed transcriptional changes in acute myeloid…”
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Phytochemical analysis and free radical scavenging activity of medicinal plants Gnidia glauca and Dioscorea bulbifera by Ghosh, Sougata, Derle, Abhishek, Ahire, Mehul, More, Piyush, Jagtap, Soham, Phadatare, Suvarna D, Patil, Ajay B, Jabgunde, Amit M, Sharma, Geeta K, Shinde, Vaishali S, Pardesi, Karishma, Dhavale, Dilip D, Chopade, Balu A

“…Gnidia glauca and Dioscorea bulbifera are traditional medicinal plants that can be considered as sources of natural antioxidants. Herein we report the…”
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ZnO Nanoparticles-Red Sandalwood Conjugate: A Promising Anti-Diabetic Agent by Kitture, Rohini, Chordiya, Kalyani, Gaware, Shankar, Ghosh, Sougata, More, Piyush A, Kulkarni, Parag, Chopade, Balu A, Kale, S N

“…With the advances in nanoscience and nanotechnology the interest of researchers has expanded to interdisciplinary domain like bio-medical applications. Among…”
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A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities by Anyaegbunam, Uchenna Alex, More, Piyush, Fontaine, Jean-Fred, Cate, Vincent Ten, Bauer, Katrin, Distler, Ute, Araldi, Elisa, Bindila, Laura, Wild, Philipp, Andrade-Navarro, Miguel A

“…Lipids are important modifiers of protein function, particularly as parts of lipoproteins, which transport lipophilic substances and mediate cellular uptake of…”
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Curcumin-Loaded, Self-Assembled Aloevera Template for Superior Antioxidant Activity and Trans-Membrane Drug Release by Kitture, Rohini, Ghosh, Sougata, More, Piyush A, Date, Kalyani, Gaware, Shankar, Datar, Suwarna, Chopade, Balu A, Kale, S N

“…Fine combination of natural botanical extracts to evaluate and maximize their medicinal efficacy has been studied for long. However, their limited shelf-life,…”
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ChIP-Seq from Limited Starting Material of K562 Cells and Drosophila Neuroblasts Using Tagmentation Assisted Fragmentation Approach by Akhtar, Junaid, More, Piyush, Albrecht, Steffen

“…Chromatin immunoprecipitation is extensively used to investigate the epigenetic profile and transcription factor binding sites in the genome. However, when the…”
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TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay by Akhtar, Junaid, More, Piyush, Albrecht, Steffen, Marini, Federico, Kaiser, Waldemar, Kulkarni, Apurva, Wojnowski, Leszek, Fontaine, Jean-Fred, Andrade-Navarro, Miguel A, Silies, Marion, Berger, Christian

“…Chromatin immunoprecipitation (ChIP) followed by next generation sequencing (ChIP-Seq) is a powerful technique to study transcriptional regulation. However,…”
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DiseaseLinc: Disease Enrichment Analysis of Sets of Differentially Expressed LincRNAs by More, Piyush, Talyan, Sweta, Fontaine, Jean-Fred, Muro, Enrique M, Andrade-Navarro, Miguel A

“…Long intergenic non-coding RNAs (LincRNAs) are long RNAs that do not encode proteins. Functional evidence is lacking for most of them. Their biogenesis is not…”
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LipiDisease: associate lipids to diseases using literature mining by More, Piyush, Bindila, Laura, Wild, Philipp, Andrade-Navarro, Miguel, Fontaine, Jean-Fred

“…Abstract Summary Lipids exhibit an essential role in cellular assembly and signaling. Dysregulation of these functions has been linked with many complications…”
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Dual Drug Conjugated Nanoparticle for Simultaneous Targeting of Mitochondria and Nucleus in Cancer Cells by Mallick, Abhik, More, Piyush, Ghosh, Sougata, Chippalkatti, Rohan, Chopade, Balu A, Lahiri, Mayurika, Basu, Sudipta

“…Effective targeting of mitochondria has emerged as an alternative strategy in cancer chemotherapy. However, considering mitochondria’s crucial role in cellular…”
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Chimeric Nanoparticle: A Platform for Simultaneous Targeting of Phosphatidylinositol-3-Kinase Signaling and Damaging DNA in Cancer Cells by Palvai, Sandeep, More, Piyush, Mapara, Nikunj, Basu, Sudipta

“…Phosphatidylinositol-3-kinase (PI3K) signaling has been hijacked in different types of cancers. Hence, PI3K inhibitors have emerged as novel targeted…”
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Cisplatin-induced self-assembly of graphene oxide sheets into spherical nanoparticles for damaging sub-cellular DNA by Nandi, Aditi, Mallick, Abhik, More, Piyush, Sengupta, Poulomi, Ballav, Nirmalya, Basu, Sudipta

“…This report describes the hitherto unobserved cisplatin induced self-assembly of 2D-graphene oxide sheets into 3D-spherical nano-scale particles. These…”
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Novel platinum-palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities by Ghosh, Sougata, Nitnavare, Rahul, Dewle, Ankush, Tomar, Geetanjali B, Chippalkatti, Rohan, More, Piyush, Kitture, Rohini, Kale, Sangeeta, Bellare, Jayesh, Chopade, Balu A

“…Medicinal plants serve as rich sources of diverse bioactive phytochemicals that might even take part in bioreduction and stabilization of phytogenic…”
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Diosgenin Functionalized Iron Oxide Nanoparticles as Novel Nanomaterial Against Breast Cancer by Ghosh, Sougata, More, Piyush, Derle, Abhishek, Kitture, Rohini, Kale, Trupti, Gorain, Mahadeo, Avasthi, Ashish, Markad, Pramod, Kundu, Gopal C, Kale, Sangeeta, Dhavale, Dilip D, Bellare, Jayesh, Chopade, Balu A

“…Iron oxide nanoparticles (IONPs) have gained immense importance recently as drug nanocarriers due to easy multifunctionalization, simultaneous targeting,…”
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Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells by More, Piyush, Goedtel-Armbrust, Ute, Shah, Viral, Mathaes, Marianne, Kindler, Thomas, Andrade-Navarro, Miguel A., Wojnowski, Leszek

“…Recently approved cancer drugs remain out-of-reach to most patients due to prohibitive costs and only few produce clinically meaningful benefits. An untapped…”
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Health-Relevant Phenotypes in the Offspring of Mice Given CAR Activators Prior to Pregnancy by Dietrich, Karin, Baumgart, Jan, Eshkind, Leonid, Reuter, Lea, Gödtel-Armbrust, Ute, Butt, Elke, Musheev, Michael, Marini, Federico, More, Piyush, Grosser, Tanja, Niehrs, Christof, Wojnowski, Leszek, Mathäs, Marianne

“…Hepatic induction in response to drugs and environmental chemicals affects drug therapies and energy metabolism. We investigated whether the induction is…”
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Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis by Spiecker, Lisa, Witte, Ines, Mehlig, Julia, Shah, Viral, Meyerhöfer, Markus, Haehnel, Patricia S., Petermann, Victoria, Schüler, Andrea, More, Piyush, Cabezas-Wallscheid, Nina, Horke, Sven, Pautz, Andrea, Daiber, Andreas, Sasca, Daniel, Kindler, Thomas, Kleinert, Hartmut

“…Background. Long-term hematopoietic stem cells (LT-HSCs) reside in bone marrow niches with tightly controlled reactive oxygen species (ROS) levels. ROS…”
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Self-Assembled Oleic Acid Nanoparticle Mediated Inhibition of Mitogen-Activated Protein Kinase Signaling in Combination with DNA Damage in Cancer Cells by Palvai, Sandeep, More, Piyush, Mapara, Nikunj, Nagraj, Jyothi, Chowdhury, Rajdeep, Basu, Sudipta

“…Mitogen‐activated protein kinase (MAPK) signaling has been dysregulated in different types of cancers. However, targeting MAPK signaling with small molecules…”
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