Search Results - "Morden, JP"
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Abstract P3-13-01: Withdrawn
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…This abstract was withdrawn by the authors…”
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Adjusting for treatment switching in randomised controlled trials – A simulation study and a simplified two-stage method
Published in Statistical methods in medical research (01-04-2017)“…Estimates of the overall survival benefit of new cancer treatments are often confounded by treatment switching in randomised controlled trials (RCTs) – whereby…”
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Assessing methods for dealing with treatment switching in clinical trials: A follow-up simulation study
Published in Statistical methods in medical research (01-03-2018)“…When patients randomised to the control group of a randomised controlled trial are allowed to switch onto the experimental treatment, intention-to-treat…”
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Adjusting Survival Time Estimates to Account for Treatment Switching in Randomized Controlled Trials—an Economic Evaluation Context: Methods, Limitations, and Recommendations
Published in Medical decision making (01-04-2014)“…Background. Treatment switching commonly occurs in clinical trials of novel interventions in the advanced or metastatic cancer setting. However, methods to…”
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Abstract GS1-03: Peri-operative aromatase inhibitor treatment in determining or predicting longterm outcome in early breast cancer – The POETIC Trial (CRUK/07/015)
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Background Experimental evidence (Fisher et al, 1989) & a small clinical trial (IMPACT) respectively suggested peri-operative endocrine therapy (ET) may…”
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Assessing methods for dealing with treatment switching in randomised controlled trials: a simulation study
Published in BMC medical research methodology (11-01-2011)“…We investigate methods used to analyse the results of clinical trials with survival outcomes in which some patients switch from their allocated treatment to…”
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Abstract S3-3: The UK TACT2 Trial: comparison of standard vs accelerated epirubicin in patients requiring chemotherapy for early breast cancer (EBC) (CRUK/05/019)
Published in Cancer research (Chicago, Ill.) (15-12-2012)“…Introduction: TACT2, a multicentre randomized phase III trial in patients with node +ve or high risk node -ve invasive EBC with E-CMF as control (Poole NEJM…”
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