Search Results - "Morchang, Atthapan"
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Alpha-mangostin inhibits dengue virus production and pro-inflammatory cytokine/chemokine expression in dendritic cells
Published in Archives of virology (01-06-2021)“…Dengue virus (DENV) is transmitted to humans via the bite of an Aedes mosquito, causing dengue fever, dengue hemorrhagic fever, or dengue shock syndrome. In…”
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Melatonin Inhibits Dengue Virus Infection via the Sirtuin 1-Mediated Interferon Pathway
Published in Viruses (11-04-2021)“…Dengue virus (DENV) is the causative pathogen in the life-threatening dengue hemorrhagic fever and dengue shock syndrome. DENV is transmitted to humans via the…”
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RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines
Published in PloS one (16-11-2017)“…Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which…”
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Role of cathepsin B in dengue virus-mediated apoptosis
Published in Biochemical and biophysical research communications (16-08-2013)“…•Dengue virus induces lysosomal membrane permeabilization.•Cathepsin B and S contribute to dengue virus-induced apoptosis.•Cathepsin B activates both caspase-9…”
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Knockdown of heat shock protein family D member 1 (HSPD1) in lung cancer cell altered secretome profile and cancer-associated fibroblast induction
Published in Biochimica et biophysica acta. Molecular cell research (01-06-2024)“…The crosstalk between lung cancer cells and cancer-associated fibroblast (CAF) is pivotal in cancer progression. Heat shock protein family D member 1 (HSPD1)…”
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Proteomic insights into the regulatory function of ARID1A in colon cancer cells
Published in Oncology letters (01-08-2024)“…The AT-rich interacting domain-containing protein 1A (ARID1A) is a tumor suppressor gene that has been implicated in several cancers, including colorectal…”
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Mathurameha ameliorates cardiovascular complications in high-fat diet/low-dose streptozotocin-induced type 2 diabetic rats: insights from histological and proteomic analysis
Published in Journal of molecular histology (01-12-2024)“…Type 2 diabetes mellitus (T2DM) is a global health concern with increasing prevalence. Mathurameha, a Thai herbal formula, has shown promising glucose-lowering…”
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GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas
Published in American journal of cancer research (01-01-2020)“…Since the prognosis for children with high-risk osteosarcoma (OS) remains suboptimal despite intensive multi-modality therapies, there is a clear and urgent…”
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Serine protease inhibitor AEBSF reduces dengue virus infection via decreased cholesterol synthesis
Published in Virus research (02-10-2019)“…•AEBSF decreases dengue viral RNA replication and protein synthesis.•AEBSF inhibits dengue virus production of all four serotypes.•Anti-DENV property of AEBSF…”
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Role of ERK1/2 signaling in dengue virus-induced liver injury
Published in Virus research (08-08-2014)“…•Gene expression profile of DENV-induced apoptosis in a mouse model.•DENV induces phosphorylation of ERK1/2 and increases liver injury.•Inhibition of…”
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Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production
Published in Biochemical and biophysical research communications (29-06-2012)“…► For the first time how DENV NS5 increases RANTES production. ► DENV NS5 physically interacts with human Daxx. ► Nuclear localization of NS5 is required for…”
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Compound A, a dissociated glucocorticoid receptor modulator, reduces dengue virus-induced cytokine secretion and dengue virus production
Published in Biochemical and biophysical research communications (28-06-2013)“…•For the first time the therapeutic potential of CpdA in dengue virus infection.•Cytokine gene expression profile in dengue virus-infected cells.•Inhibition of…”
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Inhibition of p38MAPK and CD137 signaling reduce dengue virus-induced TNF-α secretion and apoptosis
Published in Virology journal (04-04-2013)“…BACKGROUND: Hepatic injury in dengue virus (DENV) infection is authenticated by hepatomegaly and an upsurge in transaminase levels. DENV replicates in…”
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Cell death gene expression profile: Role of RIPK2 in dengue virus-mediated apoptosis
Published in Virus research (01-03-2011)“…Dengue virus (DENV) is a major emerging arthropod-borne pathogen, which infects individuals in both subtropical and tropical regions. Patients with DENV…”
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Role of CD137 signaling in dengue virus-mediated apoptosis
Published in Biochemical and biophysical research communications (08-07-2011)“…► For the first time the role of CD137 in dengue virus (DENV) infection. ► Induction of DENV-mediated apoptosis by CD137 signaling. ► Sensitization to…”
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Inhibition of p38MAPK and CD137 signaling reduce dengue virus-induced TNF-[alpha] secretion and apoptosis
Published in Virology journal (04-04-2013)“…Hepatic injury in dengue virus (DENV) infection is authenticated by hepatomegaly and an upsurge in transaminase levels. DENV replicates in hepatocytes and…”
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