Search Results - "Moravčík, Štefan"

Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes by Iosub, Andrei V, Moravčík, Štefan, Wallentin, Carl-Johan, Bergman, Joakim

“…The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst,…”
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Synthetic Route Design of AZD4635, an A2AR Antagonist by Littleson, Mairi M, Campbell, Andrew D, Clarke, Adam, Dow, Mark, Ensor, Gareth, Evans, Matthew C, Herring, Adam, Jackson, Bethany A, Jackson, Lucinda V, Karlsson, Staffan, Klauber, David J, Legg, Danny H, Leslie, Kevin W, Moravčík, Štefan, Parsons, Chris D, Ronson, Thomas O, Meadows, Rebecca E

“…The AstraZeneca approach to synthetic Route Design is exemplified through our AZD4635 chemical development program. The identification of possible new route…”
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Synthetic and Chromatographic Challenges and Strategies for Multigram Manufacture of KRAS G12C Inhibitors by Nikitidis, Grigorios, Carlsson, Anna-Carin C., Karlsson, Staffan, Campbell, Andrew D., Cook, Calum, Dai, Kuangchu, Emtenäs, Hans, Jonson, Anna C., Leek, Hanna, Malmgren, Marcus, Moravčík, Štefan, Pithani, Subhash, Tatton, Matthew R., Zhao, Hucheng, Öhlén, Kristina

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Synthetic Route Design of AZD4635, an A 2A R Antagonist by Littleson, Mairi M., Campbell, Andrew D., Clarke, Adam, Dow, Mark, Ensor, Gareth, Evans, Matthew C., Herring, Adam, Jackson, Bethany A., Jackson, Lucinda V., Karlsson, Staffan, Klauber, David J., Legg, Danny H., Leslie, Kevin W., Moravčík, Štefan, Parsons, Chris D., Ronson, Thomas O., Meadows, Rebecca E.

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Medicinal Chemistry of Oligonucleotide Drugs - Milestones of the Past and Visions for the Future by Hall, Jonathan, Ashkinadze, Anastasia, Becker, Jan Philipp, Laski, Artur, Manz, Eva-Maria, Moravčík, Štefan, Sjöström, Sebastian, Vincent, Mathilde

“…The oligonucleotide therapeutics field has blossomed in recent years, with thirteen approved drugs today and the promise of accelerated growth in coming years…”
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The pregnane X receptor down‐regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC‐1 coactivator by Hyrsova, Lucie, Smutny, Tomas, Carazo, Alejandro, Moravcik, Stefan, Mandikova, Jana, Trejtnar, Frantisek, Gerbal‐Chaloin, Sabine, Pavek, Petr

“…Background and Purpose The organic cation transporter 1 (OCT1) transports cationic drugs into hepatocytes. The high hepatic expression of OCT1 is controlled by…”
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