Search Results - "Morató, Anna"

Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts by Urbanek, Annika, Popovic, Matija, Elena-Real, Carlos A, Morató, Anna, Estaña, Alejandro, Fournet, Aurélie, Allemand, Frédéric, Gil, Ana M, Cativiela, Carlos, Cortés, Juan, Jiménez, Ana I, Sibille, Nathalie, Bernadó, Pau

“…Proline is found in a cis conformation in proteins more often than other proteinogenic amino acids, where it influences structure and modulates function, being…”
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Site-Specific Introduction of Alanines for the Nuclear Magnetic Resonance Investigation of Low-Complexity Regions and Large Biomolecular Assemblies by Elena-Real, Carlos A., Urbanek, Annika, Imbert, Lionel, Morató, Anna, Fournet, Aurélie, Allemand, Frédéric, Sibille, Nathalie, Boisbouvier, Jérôme, Bernadó, Pau

“…Nuclear magnetic resonance (NMR) studies of large biomolecular machines and highly repetitive proteins remain challenging due to the difficulty of assigning…”
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Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins by Urbanek, Annika, Popovic, Matija, Morató, Anna, Estaña, Alejandro, Elena-Real, Carlos A., Mier, Pablo, Fournet, Aurélie, Allemand, Frédéric, Delbecq, Stephane, Andrade-Navarro, Miguel A., Cortés, Juan, Sibille, Nathalie, Bernadó, Pau

“…The causative agent of Huntington's disease, the poly-Q homo-repeat in the N-terminal region of huntingtin (httex1), is flanked by a 17-residue-long fragment…”
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The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity by Elena-Real, Carlos A., Sagar, Amin, Urbanek, Annika, Popovic, Matija, Morató, Anna, Estaña, Alejandro, Fournet, Aurélie, Doucet, Christine, Lund, Xamuel L., Shi, Zhen-Dan, Costa, Luca, Thureau, Aurélien, Allemand, Frédéric, Swenson, Rolf E., Milhiet, Pierre-Emmanuel, Crehuet, Ramon, Barducci, Alessandro, Cortés, Juan, Sinnaeve, Davy, Sibille, Nathalie, Bernadó, Pau

“…Huntington’s disease is a neurodegenerative disorder caused by a CAG expansion in the first exon of the HTT gene, resulting in an extended polyglutamine…”
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Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1 by Elena-Real, Carlos A., Urbanek, Annika, Lund, Xamuel L., Morató, Anna, Sagar, Amin, Fournet, Aurélie, Estaña, Alejandro, Bellande, Tracy, Allemand, Frédéric, Cortés, Juan, Sibille, Nathalie, Melki, Ronald, Bernadó, Pau

“…Huntington’s disease neurodegeneration occurs when the number of consecutive glutamines in the huntingtin exon-1 (HTTExon1) exceeds a pathological threshold of…”
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A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats by Urbanek, Annika, Morató, Anna, Allemand, Frédéric, Delaforge, Elise, Fournet, Aurélie, Popovic, Matija, Delbecq, Stephane, Sibille, Nathalie, Bernadó, Pau

“…Homorepeat (HR) proteins are involved in key biological processes and multiple pathologies, however their high‐resolution characterization has been impaired…”
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Site‐Specific Isotopic Labeling (SSIL): Access to High‐Resolution Structural and Dynamic Information in Low‐Complexity Proteins by Urbanek, Annika, Elena‐Real, Carlos A., Popovic, Matija, Morató, Anna, Fournet, Aurélie, Allemand, Frédéric, Delbecq, Stephane, Sibille, Nathalie, Bernadó, Pau

“…Remarkable technical progress in the area of structural biology has paved the way to study previously inaccessible targets. For example, large protein…”
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Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins by Morató, Anna, Elena-Real, Carlos A, Popovic, Matija, Fournet, Aurélie, Zhang, Karen, Allemand, Frédéric, Sibille, Nathalie, Urbanek, Annika, Bernadó, Pau

“…The high-resolution structural study of huntingtin exon-1 (HttEx1) has long been hampered by its intrinsic properties. In addition to being prone to aggregate,…”
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In Vitro Bioactivation of 3-(N-Phenylamino)propane-1,2-diol by Human and Rat Liver Microsomes and Recombinant P450 Enzymes. Implications for Toxic Oil Syndrome by Martínez-Cabot, Anna, Morató, Anna, Commandeur, Jan N. M, Vermeulen, Nico P. E, Messeguer, Angel

“…Toxic oil syndrome (TOS) was a massive food-borne intoxication that occurred in Spain in 1981. Epidemiological studies imputed…”
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LC-MS ion maps for the characterization of aniline derivatives of fatty acids and triglycerides in laboratory-denatured rapeseed oil by Reig, Natalia, Calaf, Rosa E., Messeguer, Angel, Morató, Anna, Escabros, Jordi, Gelpí, Emilio, Abian, Joaquín

“…In 1981 Spain went through a unique epidemic associated with a food‐borne vector, affecting more than 20 000 people with over 800 deaths, which came to be…”
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Synthesis and Stability Studies of the Glutathione and N-Acetylcysteine Adducts of an Iminoquinone Reactive Intermediate Generated in the Biotransformation of 3-(N-Phenylamino)propane-1,2-diol:  Implications for Toxic Oil Syndrome by Martínez-Cabot, Anna, Morató, Anna, Messeguer, Angel

“…Epidemiological studies have pointed to fatty acid mono- and diesters of 3-(N-phenylamino)propane-1,2-diol (PAP) as the biomarkers of the toxic oil batches…”
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Biotransformation and Clearance of 3-(Phenylamino)propane-1,2-diol, a Compound Present in Samples Related to Toxic Oil Syndrome, in C57BL/6 and A/J Mice by Ladona, Margarita G, Bujons, Jordi, Messeguer, Angel, Ampurdanés, Coral, Morató, Anna, Corbella, Jacint

“…In May 1981, a massive food-borne intoxication occurred in Spain. The so-called toxic oil syndrome (TOS) was associated with the consumption of…”
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Flanking regions determine the structure of the poly-glutamine homo- repeat in huntingtin through mechanisms common among glutamine-rich human proteins by Urbanek, Annika N, Popovic, Matija, Morató, Anna, Estaña, Alejandro N, Elena-Real, Carlos A, Mier, Pablo, Fournet, Aurélie, Allemand, Frédéric, Delbecq, Stéphane, Andrade-Navarro, Miguel A, Cortés, Juan, Sibille, Nathalie, Bernadó, Pau N

“…The causative agent of Huntington's disease, the poly-Q homo-repeat in the N-terminal region of huntingtin (httex1), is flanked by a 17-residue-long fragment…”
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Factors associated with 30-day readmission after hospitalisation for community-acquired pneumonia in older patients: a cross-sectional study in seven Spanish regions by Toledo, Diana, Soldevila, Núria, Torner, Núria, Pérez-Lozano, María José, Espejo, Elena, Navarro, Gemma, Egurrola, Mikel, Domínguez, Ángela

“…ObjectiveHospital readmission in patients admitted for community-acquired pneumonia (CAP) is frequent in the elderly and patients with multiple comorbidities,…”
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Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients by Soto, Marcelo, Sampietro-Colom, Laura, Vilella, Anna, Pantoja, Efraín, Asenjo, María, Arjona, Ruth, Hurtado, Juan Carlos, Trilla, Antoni, Alvarez-Martínez, Míriam José, Mira, Aurea, Vila, Jordi, Marcos, María Angeles

“…Seasonal influenza causes significant morbidity and mortality and has a substantial economic impact on the healthcare system. The main objective of this study…”
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Etiological, Clinical, and Epidemiological Characteristics of Acute Viral Gastroenteritis in an Adult Population in a Tertiary Level Hospital in Spain by Herranz-Ulldemolins, Sara, Sellarès-Crous, Anna, Álvarez-Martínez, Miriam J., Valls, M. Eugenia, Aldea Novo, Marta, Vilella Morató, Anna, Rodriguez, Laura, Navarro, Mireia, Vendrell, Roser, Barrachina, Josep, Martínez, Miguel J., Marcos, M. Ángeles

“…Acute gastroenteritis (AGE) represents a significant global health burden, with enteric viruses being a leading cause of gastroenteritis worldwide. Despite…”
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Risk of covid-19 spread by undiagnosed cases in inpatients at a large tertiary hospital: transmission dynamics and learnings of two-year experience of surveillance (2020-2022) by Barón Miras, Lourdes, Torralbo, Blanca, Torá-Rocamora, Isabel, Bertrán-Luengo, María, Trilla, Antoni, Santana, Gemina, Fortes, Isabel, Rodríguez, Laura, Valls, Silvia, Gualda-Gea, Juan, Tortajada, Marta, Vilella-Morató, Anna

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Viscerotropic disease: Case definition and guidelines for collection, analysis, and presentation of immunization safety data by Gershman, Mark D, Staples, J. Erin, Bentsi-Enchill, Adwoa D, Breugelmans, J. Gabrielle, Brito, Glacus S, Bastos Camacho, Luiz Antonio, Cottin, Pascale, Domingo, Cristina, Durbin, Anna, Gascon, Joaquim, Guenaneche, Fouzia, Hayes, Edward B, Jelenik, Zsuzsanna, Khromava, Alena, Martins, Reinaldo de Menezes, Wilson, Mario Masana, Massy, Nathalie, Nasidi, Abdulsalami, Niedrig, Matthias, Sherwat, Adam, Tsai, Theodore, Vilella, Anna, Wilson, Mary Elizabeth, Kohl, Katrin S

“…The YFWG included staff of the US Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), various US academic institutions, the US…”
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Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients by Soto, Marcelo, Sampietro-Colom, Laura, Vilella i Morató, Anna, Pantoja, Efraín, Asenjo, María, Arjona, Ruth, Hurtado, Juan Carlos, Trilla García, Antoni, Álvarez Martínez, Míriam, Mira, Aurea, Vila Estapé, Jordi, Marcos Maeso, Ma. Angeles

“…Seasonal influenza causes significant morbidity and mortality and has a substantial economic impact on the healthcare system. The main objective of this study…”
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Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients by Soto, Marcelo, Sampietro-Colom, Laura, Vilella i Morató, Anna, Pantoja, Efraín, Asenjo, María, Arjona, Ruth, Hurtado, Juan Carlos, Trilla García, Antoni, Álvarez Martínez, Míriam, Mira, Aurea, Vila Estapé, Jordi, Marcos Maeso, Ma. Angeles

“…Seasonal influenza causes significant morbidity and mortality and has a substantial economic impact on the healthcare system. The main objective of this study…”
Get full text