Search Results - "Morato, Laia"

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle by Pirinen, Eija, Cantó, Carles, Jo, Young Suk, Morato, Laia, Zhang, Hongbo, Menzies, Keir J., Williams, Evan G., Mouchiroud, Laurent, Moullan, Norman, Hagberg, Carolina, Li, Wei, Timmers, Silvie, Imhof, Ralph, Verbeek, Jef, Pujol, Aurora, van Loon, Barbara, Viscomi, Carlo, Zeviani, Massimo, Schrauwen, Patrick, Sauve, Anthony A., Schoonjans, Kristina, Auwerx, Johan

“…We previously demonstrated that the deletion of the poly(ADP-ribose)polymerase (Parp)-1 gene in mice enhances oxidative metabolism, thereby protecting against…”
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Therapeutic potential of glutathione-enhancers in stress-related psychopathologies by Zalachoras, Ioannis, Hollis, Fiona, Ramos-Fernández, Eva, Trovo, Laura, Sonnay, Sarah, Geiser, Eveline, Preitner, Nicolas, Steiner, Pascal, Sandi, Carmen, Morató, Laia

“…[Display omitted] •Mitochondria meet the high energetic demand of the brain during psychogenic stress.•Chronic stress leads to oxidative stress and lower…”
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Mitochondrial dysfunction in central nervous system white matter disorders by Morató, Laia, Bertini, Enrico, Verrigni, Daniela, Ardissone, Anna, Ruiz, Montse, Ferrer, Isidre, Uziel, Graziella, Pujol, Aurora

“…Defects of mitochondrial respiration and function had been proposed as a major culprit in the most common neurodegenerative diseases, including prototypic…”
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Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy by Schlüter, Agatha, Espinosa, Lluís, Fourcade, Stéphane, Galino, Jorge, López, Eva, Ilieva, Ekaterina, Morató, Laia, Asheuer, Muriel, Cook, Ted, McLaren, Alistair, Reid, Juliet, Kelly, Fiona, Bates, Stewart, Aubourg, Patrick, Galea, Elena, Pujol, Aurora

“…X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder characterized by axonopathy and demyelination in the central nervous system and adrenal…”
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance by Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz‐Cortés, Tatiana, Jové, Mariona, Naudí, Alba, Martínez‐Redondo, Paloma, Dierssen, Mara, Ferrer, Isidre, Villarroya, Francesc, Pamplona, Reinald, Vaquero, Alejandro, Portero‐Otín, Manel, Pujol, Aurora

“…Summary Sirtuin 2 (SIRT2) is a member of a family of NAD+‐dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially…”
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Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy by MORATO, Laia, GALINO, Jorge, PAMPLONA, Reinald, GALEA, Elena, FLINT BEAL, M, FERRER, Isidre, FOURCADE, Stéphane, PUJOL, Aurora, RUIZ, Montserrat, YLAGAN CALINGASAN, Noel, STARKOV, Anatoly A, DUMONT, Magali, NAUDI, Alba, MARTINEZ, Juan Jose, AUBOURG, Patrick, PORTERO-OTIN, Manuel

“…X-linked adrenoleukodystrophy is a neurometabolic disorder caused by inactivation of the peroxisomal ABCD1 transporter of very long-chain fatty acids. In mice,…”
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eNAMPT actions through nucleus accumbens NAD + /SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress by Morató, Laia, Astori, Simone, Zalachoras, Ioannis, Rodrigues, Joao, Ghosal, Sriparna, Huang, Wei, Guillot de Suduiraut, Isabelle, Grosse, Jocelyn, Zanoletti, Olivia, Cao, Lei, Auwerx, Johan, Sandi, Carmen

“…Obesity is frequently associated with impairments in the social domain, and stress at puberty can lead to long-lasting changes in visceral fat deposition and…”
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Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus‐Merzbacher disease by Ruiz, Montserrat, Bégou, Mélina, Launay, Nathalie, Ranea‐Robles, Pablo, Bianchi, Patrizia, López‐Erauskin, Jone, Morató, Laia, Guilera, Cristina, Petit, Bérengère, Vaurs‐Barriere, Catherine, Guéret‐Gonthier, Céline, Bonnet‐Dupeyron, Marie‐Noëlle, Fourcade, Stéphane, Auwerx, Johan, Boespflug‐Tanguy, Odile, Pujol, Aurora

“…Pelizaeus‐Merzbacher disease (PMD) is a fatal hypomyelinating disorder characterized by early impairment of motor development, nystagmus, choreoathetotic…”
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Oxidative stress and mitochondrial dynamics malfunction are linked in P elizaeus‐ M erzbacher disease by Ruiz, Montserrat, Bégou, Mélina, Launay, Nathalie, Ranea‐Robles, Pablo, Bianchi, Patrizia, López‐Erauskin, Jone, Morató, Laia, Guilera, Cristina, Petit, Bérengère, Vaurs‐Barriere, Catherine, Guéret‐Gonthier, Céline, Bonnet‐Dupeyron, Marie‐Noëlle, Fourcade, Stéphane, Auwerx, Johan, Boespflug‐Tanguy, Odile, Pujol, Aurora

“…Abstract Pelizaeus‐Merzbacher disease (PMD) is a fatal hypomyelinating disorder characterized by early impairment of motor development, nystagmus,…”
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Loss of SIRT 2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance by Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz‐Cortés, Tatiana, Jové, Mariona, Naudí, Alba, Martínez‐Redondo, Paloma, Dierssen, Mara, Ferrer, Isidre, Villarroya, Francesc, Pamplona, Reinald, Vaquero, Alejandro, Portero‐Otín, Manel, Pujol, Aurora

“…Summary Sirtuin 2 ( SIRT 2) is a member of a family of NAD + ‐dependent histone deacetylases ( HDAC ) that play diverse roles in cellular metabolism and…”
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance by Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora

“…Sirtuin 2 (SIRT2) is a member of a family of NAD+ -dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for…”
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance by Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora

“…Sirtuin 2 (SIRT2) is a member of a family of NAD+ -dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for…”
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance by Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora

“…Sirtuin 2 (SIRT2) is a member of a family of NAD+ -dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for…”
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