Search Results - "Morar, Neetha"
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Prevention, Partners, and Power Imbalances: Women's Views on How Male Partners Affected Their Adherence to Vaginal Microbicide Gels During HIV Prevention Trials in Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-12-2020)“…BACKGROUND:Low adherence has contributed to disappointing results for trials testing vaginal microbicides for HIV prevention. This study engaged former gel…”
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Women design their own vaginal microbicide trial: Suggestions on how to improve adherence from former participants of HIV prevention trials
Published in PloS one (07-01-2021)“…Low adherence in vaginal microbicide clinical trials for HIV prevention has impeded interpretation of trial results and hindered evaluation of potentially…”
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A Simple Risk Prediction Algorithm for HIV Transmission: Results from HIV Prevention Trials in KwaZulu Natal, South Africa (2002–2012)
Published in AIDS and behavior (2018)“…We aimed to develop a HIV risk scoring algorithm for targeted screening among women in South Africa. We used data from five biomedical intervention trials…”
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A mixed methods and triangulation model for increasing the accuracy of adherence and sexual behaviour data: the Microbicides Development Programme
Published in PloS one (21-07-2010)“…The collection of accurate data on adherence and sexual behaviour is crucial in microbicide (and other HIV-related) research. In the absence of a "gold…”
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Male Partner Opinions of the Dapivirine Vaginal Ring Used During an Open-Label Extension HIV Prevention Trial in KwaZulu-Natal, South Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2023)“…The dapivirine vaginal ring ("the ring") reduced HIV acquisition by about 35% in phase III trials, with modeling from open-label extension trials estimating…”
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Qualitative Perceptions of Dapivirine VR Adherence and Drug Level Feedback Following an Open-Label Extension Trial
Published in Journal of acquired immune deficiency syndromes (1999) (01-04-2021)“…There continues to be a need for HIV prevention options that women can initiate and use autonomously. The dapivirine vaginal ring (VR) has been shown to have a…”
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Men’s Sexual Experiences with the Dapivirine Vaginal Ring in Malawi, South Africa, Uganda and Zimbabwe
Published in AIDS and behavior (01-06-2021)“…The dapivirine vaginal ring has been well-tolerated and shown to prevent HIV in clinical trials. The ring is female initiated, yet endorsement for use is…”
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Impact and experience of participant engagement activities in supporting dapivirine ring use among participants enrolled in the phase III MTN-020/ASPIRE study
Published in BMC public health (08-11-2021)“…Low adherence to investigational products can negatively impact study outcomes, limiting the ability to demonstrate efficacy. To continue advancing potential…”
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Perceptions of the "Fabric" - An exploratory study of a novel multi-purpose technology among women in Sub Saharan Africa
Published in PloS one (31-10-2018)“…HIV and pregnancy prevention are dual health priorities for women, and particularly in sub-Saharan Africa. Drug-eluting fibers offer a dosage form that…”
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Assessing the accuracy of adherence and sexual behaviour data in the MDP301 vaginal microbicides trial using a mixed methods and triangulation model
Published in PloS one (21-07-2010)“…Accurate data on adherence and sexual behaviour are crucial in microbicide (and other HIV-related) research. In the absence of a "gold standard" the collection…”
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Ring-ing in the Future: Participant and Male Partner Perspectives Regarding Future Use of the Dapivirine Vaginal Ring for HIV Prevention
Published in AIDS and behavior (01-06-2022)“…Women account for a disproportionate percentage of new HIV infections in sub-Saharan Africa indicating a need for female-initiated HIV prevention options…”
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Research participants’ skills development as HIV prevention peer educators in their communities
Published in Journal of health psychology (01-09-2018)“…This article describes the influence of a peer education programme on skills development among 22 women participating in HIV prevention trials. Interviews were…”
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Qualitative perceptions of dapivirine vaginal ring adherence and drug level feedback following an open-label extension trial
Published in Journal of acquired immune deficiency syndromes (1999) (01-04-2021)“…BACKGROUND:There continues to be a need for HIV prevention options that women can initiate and use autonomously. The dapivirine vaginal ring (VR) has been…”
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South Africa's experience of the closure of the cellulose sulphate microbicide trial
Published in PLoS medicine (01-07-2007)“…Abbreviations: CS, cellulose sulphate; DOH, Department of Health; DSMC, data safety and monitoring committee; HPRU, HIV Prevention Research Unit; MRC, Medical…”
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Re-framing microbicide acceptability: findings from the MDP301 trial
Published in Culture, health & sexuality (01-08-2010)“…Microbicides are most usually conceptualised within a disease prevention framework and studies usually define acceptability in terms of product…”
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Participants as community-based peer educators: impact on a clinical trial site in KwaZulu-Natal
Published in South African Journal of Science (01-07-2013)“…Participant recruitment, retention and product adherence are necessary to measure the efficacy or effectiveness of an intervention in a clinical trial. As part…”
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Microbicide acceptability research: current approaches and future directions
Published in Social science & medicine (1982) (2005)“…With growing recognition of the potential value of microbicides for HIV/STI prevention, the importance of the acceptability of this brand-new technology has…”
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"We Have Our Protector": Misperceptions of Protection Against HIV Among Participants in a Microbicide Efficacy Trial
Published in American journal of public health (1971) (01-06-2006)“…We examined perceptions of the effectiveness and acceptability of a candidate microbicide among 94 South African female sex workers who had participated in a…”
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To tell or not to tell: male partner engagement in a Phase 3 microbicide efficacy trial in South Africa
Published in Culture, health & sexuality (14-09-2015)“…Gender norms that privilege men's sexual power and pleasure, and distrust of condom use in intimate relationships, leave women vulnerable to HIV and other…”
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Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa
Published in AIDS research and therapy (27-09-2007)“…When on the market, microbicides are likely to be used by individuals who do not know their HIV status. Hence, assessment of safety and acceptability among HIV…”
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